Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling LA Sena, S Li, A Jairaman, M Prakriya, T Ezponda, DA Hildeman, ... Immunity 38 (2), 225-236, 2013 | 1108 | 2013 |
Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim DA Hildeman, Y Zhu, TC Mitchell, P Bouillet, A Strasser, J Kappler, ... Immunity 16 (6), 759-767, 2002 | 733 | 2002 |
An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder MB Jordan, D Hildeman, J Kappler, P Marrack Blood 104 (3), 735-743, 2004 | 727 | 2004 |
Reactive oxygen species regulate activation-induced T cell apoptosis DA Hildeman, T Mitchell, TK Teague, P Henson, BJ Day, J Kappler, ... Immunity 10 (6), 735-744, 1999 | 555 | 1999 |
T cells compete for access to antigen-bearing antigen-presenting cells RM Kedl, WA Rees, DA Hildeman, B Schaefer, T Mitchell, J Kappler, ... The Journal of experimental medicine 192 (8), 1105-1114, 2000 | 533 | 2000 |
× Phosphorylation of Bax Ser184 by Akt Regulates Its Activity and Apoptosis in Neutrophils SJ Gardai, DA Hildeman, SK Frankel, BB Whitlock, SC Frasch, ... Journal of Biological Chemistry 279 (20), 21085-21095, 2004 | 503 | 2004 |
The immune cell landscape in kidneys of patients with lupus nephritis A Arazi, DA Rao, CC Berthier, A Davidson, Y Liu, PJ Hoover, A Chicoine, ... Nature immunology 20 (7), 902-914, 2019 | 482 | 2019 |
Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation CS Lages, I Suffia, PA Velilla, B Huang, G Warshaw, DA Hildeman, ... The Journal of Immunology 181 (3), 1835-1848, 2008 | 396 | 2008 |
Molecular mechanisms of activated T cell death in vivo DA Hildeman, Y Zhu, TC Mitchell, J Kappler, P Marrack Current opinion in immunology 14 (3), 354-359, 2002 | 367 | 2002 |
IL-7 promotes T cell viability, trafficking, and functionality and improves survival in sepsis J Unsinger, M McGlynn, KR Kasten, AS Hoekzema, E Watanabe, ... The Journal of immunology 184 (7), 3768-3779, 2010 | 358 | 2010 |
Nonredundant roles for B cell-derived IL-10 in immune counter-regulation R Madan, F Demircik, S Surianarayanan, JL Allen, S Divanovic, ... The Journal of Immunology 183 (4), 2312-2320, 2009 | 321 | 2009 |
C5a negatively regulates toll-like receptor 4-induced immune responses H Hawlisch, Y Belkaid, R Baelder, D Hildeman, C Gerard, J Köhl Immunity 22 (4), 415-426, 2005 | 311 | 2005 |
Homeostasis of αβ TCR+ T cells P Marrack, J Bender, D Hildeman, M Jordan, T Mitchell, M Murakami, ... Nature immunology 1 (2), 107-111, 2000 | 311 | 2000 |
Immunological adjuvants promote activated T cell survival via induction of Bcl-3 TC Mitchell, D Hildeman, RM Kedl, TK Teague, BC Schaefer, J White, ... Nature immunology 2 (5), 397-402, 2001 | 293 | 2001 |
Control of Bcl-2 expression by reactive oxygen species DA Hildeman, T Mitchell, B Aronow, S Wojciechowski, J Kappler, ... Proceedings of the National Academy of Sciences 100 (25), 15035-15040, 2003 | 291 | 2003 |
Activation changes the spectrum but not the diversity of genes expressed by T cells TK Teague, D Hildeman, RM Kedl, T Mitchell, W Rees, BC Schaefer, ... Proceedings of the National Academy of Sciences 96 (22), 12691-12696, 1999 | 275 | 1999 |
Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis S Wojciechowski, P Tripathi, T Bourdeau, L Acero, HL Grimes, JD Katz, ... The Journal of experimental medicine 204 (7), 1665-1675, 2007 | 270 | 2007 |
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells W Pierson, B Cauwe, A Policheni, SM Schlenner, D Franckaert, J Berges, ... Nature immunology 14 (9), 959-965, 2013 | 233 | 2013 |
T cell apoptosis and reactive oxygen species DA Hildeman, T Mitchell, J Kappler, P Marrack The Journal of clinical investigation 111 (5), 575-581, 2003 | 212 | 2003 |
Cutting edge: emergence of CD127high functionally competent memory T cells is compromised by high viral loads and inadequate T cell help MJ Fuller, DA Hildeman, S Sabbaj, DE Gaddis, AE Tebo, L Shang, ... The journal of immunology 174 (10), 5926-5930, 2005 | 191 | 2005 |