Anion− aromatic bonding: a case for anion recognition by π-acidic rings M Mascal, A Armstrong, MD Bartberger Journal of the American Chemical Society 124 (22), 6274-6276, 2002 | 679 | 2002 |
A survey of the role of noncovalent sulfur interactions in drug design BR Beno, KS Yeung, MD Bartberger, LD Pennington, NA Meanwell Journal of medicinal chemistry 58 (11), 4383-4438, 2015 | 675 | 2015 |
Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors BA Lanman, JR Allen, JG Allen, AK Amegadzie, KS Ashton, SK Booker, ... Journal of medicinal chemistry 63 (1), 52-65, 2019 | 507 | 2019 |
The reduction potential of nitric oxide (NO) and its importance to NO biochemistry MD Bartberger, W Liu, E Ford, KM Miranda, C Switzer, JM Fukuto, ... Proceedings of the National Academy of Sciences 99 (17), 10958-10963, 2002 | 418 | 2002 |
A standard set of pericyclic reactions of hydrocarbons for the benchmarking of computational methods: the performance of ab initio, density functional, CASSCF, CASPT2, and CBS … V Guner, KS Khuong, AG Leach, PS Lee, MD Bartberger, KN Houk The Journal of Physical Chemistry A 107 (51), 11445-11459, 2003 | 414 | 2003 |
Discovery of AMG 232, a potent, selective, and orally bioavailable MDM2–p53 inhibitor in clinical development D Sun, Z Li, Y Rew, M Gribble, MD Bartberger, HP Beck, J Canon, A Chen, ... Journal of medicinal chemistry 57 (4), 1454-1472, 2014 | 332 | 2014 |
A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system KM Miranda, N Paolocci, T Katori, DD Thomas, E Ford, MD Bartberger, ... Proceedings of the National Academy of Sciences 100 (16), 9196-9201, 2003 | 319 | 2003 |
Insertion of helium and molecular hydrogen through the orifice of an open fullerene Y Rubin, T Jarrosson, GW Wang, MD Bartberger, KN Houk, G Schick, ... Angewandte Chemie 113 (8), 1591-1594, 2001 | 296 | 2001 |
The magnitude of [C− H⊙⊙⊙ O] hydrogen bonding in molecular and supramolecular assemblies FM Raymo, MD Bartberger, KN Houk, JF Stoddart Journal of the American Chemical Society 123 (38), 9264-9267, 2001 | 272 | 2001 |
The physiological chemistry and biological activity of nitroxyl (HNO): the neglected, misunderstood, and enigmatic nitrogen oxide JM Fukuto, MD Bartberger, AS Dutton, N Paolocci, DA Wink, KN Houk Chemical research in toxicology 18 (5), 790-801, 2005 | 235 | 2005 |
On the acidity and reactivity of HNO in aqueous solution and biological systems MD Bartberger, JM Fukuto, KN Houk Proceedings of the National Academy of Sciences 98 (5), 2194-2198, 2001 | 215 | 2001 |
Structure-based design of novel inhibitors of the MDM2–p53 interaction Y Rew, D Sun, F Gonzalez-Lopez De Turiso, MD Bartberger, HP Beck, ... Journal of medicinal chemistry 55 (11), 4936-4954, 2012 | 200 | 2012 |
Discovery and optimization of chromenotriazolopyrimidines as potent inhibitors of the mouse double minute 2− tumor protein 53 protein− protein interaction JG Allen, MP Bourbeau, GE Wohlhieter, MD Bartberger, K Michelsen, ... Journal of Medicinal Chemistry 52 (22), 7044-7053, 2009 | 192 | 2009 |
From fragment screening to in vivo efficacy: optimization of a series of 2-aminoquinolines as potent inhibitors of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) Y Cheng, TC Judd, MD Bartberger, J Brown, K Chen, RT Fremeau Jr, ... Journal of medicinal chemistry 54 (16), 5836-5857, 2011 | 161 | 2011 |
S−N Dissociation Energies of S-Nitrosothiols: On the Origins of Nitrosothiol Decomposition Rates MD Bartberger, JD Mannion, SC Powell, JS Stamler, KN Houk, EJ Toone Journal of the American Chemical Society 123 (36), 8868-8869, 2001 | 160 | 2001 |
Photophysics of π-conjugated polymers that incorporate metal to ligand charge transfer chromophores KD Ley, CE Whittle, MD Bartberger, KS Schanze Journal of the American Chemical Society 119 (14), 3423-3424, 1997 | 159 | 1997 |
Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins: a chemical discussion of the differential biological effects of these redox related products of NOS KM Miranda, RW Nims, DD Thomas, MG Espey, D Citrin, MD Bartberger, ... Journal of inorganic biochemistry 93 (1-2), 52-60, 2003 | 148 | 2003 |
Theory, spectroscopy, and crystallographic analysis of S-nitrosothiols: conformational distribution dictates spectroscopic behavior MD Bartberger, KN Houk, SC Powell, JD Mannion, KY Lo, JS Stamler, ... Journal of the American Chemical Society 122 (24), 5889-5890, 2000 | 139 | 2000 |
Systematic Study of the Glutathione (GSH) Reactivity of N-Arylacrylamides: 1. Effects of Aryl Substitution VJ Cee, LP Volak, Y Chen, MD Bartberger, C Tegley, T Arvedson, ... Journal of Medicinal Chemistry 58 (23), 9171-9178, 2015 | 127 | 2015 |
Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors DJ Lloyd, DJ St Jean Jr, RJM Kurzeja, RC Wahl, K Michelsen, R Cupples, ... Nature 504 (7480), 437-440, 2013 | 106 | 2013 |