Selection bias at the heterosexual HIV-1 transmission bottleneck JM Carlson, M Schaefer, DC Monaco, R Batorsky, DT Claiborne, J Prince, ... Science 345 (6193), 1254031, 2014 | 292 | 2014 |
Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression DT Claiborne, JL Prince, E Scully, G Macharia, L Micci, B Lawson, ... Proceedings of the National Academy of Sciences 112 (12), E1480-E1489, 2015 | 117 | 2015 |
Role of transmitted Gag CTL polymorphisms in defining replicative capacity and early HIV-1 pathogenesis JL Prince, DT Claiborne, JM Carlson, M Schaefer, T Yu, S Lahki, ... PLoS pathogens 8 (11), e1003041, 2012 | 112 | 2012 |
Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo CR Maldini, DT Claiborne, K Okawa, T Chen, DL Dopkin, X Shan, ... Nature medicine 26 (11), 1776-1787, 2020 | 80 | 2020 |
Impact of HLA-B* 81-associated mutations in HIV-1 Gag on viral replication capacity JK Wright, VL Naidoo, ZL Brumme, JL Prince, DT Claiborne, PJR Goulder, ... Journal of virology 86 (6), 3193-3199, 2012 | 78 | 2012 |
Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmic domain results in a loss of Env-mediated fusion and infectivity SJ Bhakta, L Shang, JL Prince, DT Claiborne, E Hunter Retrovirology 8, 1-17, 2011 | 61 | 2011 |
Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients L Yue, KJ Pfafferott, J Baalwa, K Conrod, CC Dong, C Chui, R Rong, ... PLoS pathogens 11 (1), e1004565, 2015 | 56 | 2015 |
HIV-1 variants are archived throughout infection and persist in the reservoir K Brooks, BR Jones, DA Dilernia, DJ Wilkins, DT Claiborne, S McInally, ... PLoS pathogens 16 (6), e1008378, 2020 | 44 | 2020 |
Balance between transmitted HLA preadapted and nonassociated polymorphisms is a major determinant of HIV-1 disease progression DC Mónaco, DA Dilernia, A Fiore-Gartland, T Yu, JL Prince, KK Dennis, ... Journal of Experimental Medicine 213 (10), 2049-2063, 2016 | 39 | 2016 |
Particle infectivity of HIV-1 full-length genome infectious molecular clones in a subtype C heterosexual transmission pair following high fidelity amplification and unbiased … MJ Deymier, DT Claiborne, Z Ende, HK Ratner, W Kilembe, S Allen, ... Virology 468, 454-461, 2014 | 27 | 2014 |
Immunization of BLT humanized mice redirects T cell responses to Gag and reduces acute HIV-1 viremia DT Claiborne, TE Dudek, CR Maldini, KA Power, M Ghebremichael, ... Journal of virology 93 (20), 10.1128/jvi. 00814-19, 2019 | 21 | 2019 |
Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis W Zhou, H Liu, Z Yuan, J Zundell, M Towers, J Lin, S Lombardi, H Nie, ... Cancer cell 41 (4), 740-756. e10, 2023 | 17 | 2023 |
Wide variation in susceptibility of transmitted/founder HIV-1 subtype C Isolates to protease inhibitors and association with in vitro replication efficiency KA Sutherland, DA Collier, DT Claiborne, JL Prince, MJ Deymier, ... Scientific reports 6 (1), 38153, 2016 | 16 | 2016 |
A restriction enzyme based cloning method to assess the in vitro replication capacity of HIV-1 subtype C Gag-MJ4 chimeric viruses DT Claiborne, JL Prince, E Hunter JoVE (Journal of Visualized Experiments), e51506, 2014 | 15 | 2014 |
Innate immune reconstitution in humanized bone marrow-liver-thymus (HuBLT) mice governs adaptive cellular immune function and responses to HIV-1 infection WF Garcia-Beltran, DT Claiborne, CR Maldini, M Phelps, V Vrbanac, ... Frontiers in Immunology 12, 667393, 2021 | 14 | 2021 |
Better Viral Control despite Higher CD4+ T Cell Activation during Acute HIV-1 Infection in Zambian Women Is Linked to the Sex Hormone Estradiol E El-Badry, G Macharia, D Claiborne, K Brooks, DA Dilernia, P Goepfert, ... Journal of Virology 94 (16), 10.1128/jvi. 00758-20, 2020 | 14 | 2020 |
Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis DT Claiborne, EP Scully, CD Palmer, JL Prince, GN Macharia, ... PLoS pathogens 15 (8), e1007981, 2019 | 13 | 2019 |
HLA class I downregulation by HIV-1 variants from subtype C transmission pairs Z Ende, MJ Deymier, DT Claiborne, JL Prince, DC Monaco, W Kilembe, ... Journal of virology 92 (7), 10.1128/jvi. 01633-17, 2018 | 13 | 2018 |
Poly I:C and STING agonist‐primed DC increase lymphoid tissue polyfunctional HIV‐1‐specific CD8+ T cells and limit CD4+ T‐cell loss in BLT mice M Calvet‐Mirabent, DT Claiborne, M Deruaz, S Tanno, C Serra, ... European journal of immunology 52 (3), 447-461, 2022 | 12 | 2022 |
Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer KD Miller, S O’Connor, KA Pniewski, T Kannan, R Acosta, G Mirji, S Papp, ... Nature Cancer 4 (10), 1491-1507, 2023 | 11 | 2023 |