| Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion V Lyssenko, CLF Nagorny, MR Erdos, N Wierup, A Jonsson, P Spégel, ... Nature genetics 41 (1), 82-88, 2009 | 853 | 2009 |
| Functional and molecular defects of pancreatic islets in human type 2 diabetes S Del Guerra, R Lupi, L Marselli, M Masini, M Bugliani, S Sbrana, S Torri, ... Diabetes 54 (3), 727-735, 2005 | 599 | 2005 |
| The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients P Marchetti, M Bugliani, R Lupi, L Marselli, M Masini, U Boggi, F Filipponi, ... Diabetologia 50, 2486-2494, 2007 | 519 | 2007 |
| DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients M Volkmar, S Dedeurwaerder, DA Cunha, MN Ndlovu, M Defrance, ... The EMBO journal 31 (6), 1405-1426, 2012 | 483 | 2012 |
| Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin P Marchetti, S Del Guerra, L Marselli, R Lupi, M Masini, M Pollera, ... The Journal of Clinical Endocrinology & Metabolism 89 (11), 5535-5541, 2004 | 452 | 2004 |
| Beta cell hubs dictate pancreatic islet responses to glucose NR Johnston, RK Mitchell, E Haythorne, MP Pessoa, F Semplici, J Ferrer, ... Cell metabolism 24 (3), 389-401, 2016 | 446 | 2016 |
| Autophagy in human type 2 diabetes pancreatic beta cells M Masini, M Bugliani, R Lupi, S Del Guerra, U Boggi, F Filipponi, ... Diabetologia 52, 1083-1086, 2009 | 410 | 2009 |
| RNA sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate M Cnop, B Abdulkarim, G Bottu, DA Cunha, M Igoillo-Esteve, M Masini, ... Diabetes 63 (6), 1978-1993, 2014 | 285 | 2014 |
| A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets P Marchetti, R Lupi, M Bugliani, CL Kirkpatrick, G Sebastiani, FA Grieco, ... Diabetologia 55, 3262-3272, 2012 | 271 | 2012 |
| Lipotoxicity disrupts incretin-regulated human β cell connectivity DJ Hodson, RK Mitchell, EA Bellomo, G Sun, L Vinet, P Meda, D Li, WH Li, ... The Journal of clinical investigation 123 (10), 4182-4194, 2013 | 237 | 2013 |
| Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms F Brozzi, TR Nardelli, M Lopes, I Millard, J Barthson, M Igoillo-Esteve, ... Diabetologia 58, 2307-2316, 2015 | 232 | 2015 |
| Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARγ2 in the modulation of insulin secretion R Lupi, S Del Guerra, L Marselli, M Bugliani, U Boggi, F Mosca, ... American Journal of Physiology-Endocrinology and Metabolism 286 (4), E560-E567, 2004 | 203 | 2004 |
| PTPN2, a candidate gene for type 1 diabetes, modulates interferon-γ–induced pancreatic β-cell apoptosis F Moore, ML Colli, M Cnop, MI Esteve, AK Cardozo, DA Cunha, ... Diabetes 58 (6), 1283-1291, 2009 | 196 | 2009 |
| Gliclazide protects human islet beta‐cells from apoptosis induced by intermittent high glucose S Del Guerra, M Grupillo, M Masini, R Lupi, M Bugliani, S Torri, U Boggi, ... Diabetes/metabolism research and reviews 23 (3), 234-238, 2007 | 192 | 2007 |
| Conventional and neo-antigenic peptides presented by β cells are targeted by circulating naïve CD8+ T cells in type 1 diabetic and healthy donors S Gonzalez-Duque, ME Azoury, ML Colli, G Afonso, JV Turatsinze, L Nigi, ... Cell metabolism 28 (6), 946-960. e6, 2018 | 186 | 2018 |
| Hepatitis C virus infection and human pancreatic β-cell dysfunction M Masini, D Campani, U Boggi, M Menicagli, N Funel, M Pollera, R Lupi, ... Diabetes care 28 (4), 940-941, 2005 | 181 | 2005 |
| ADCY5 couples glucose to insulin secretion in human islets DJ Hodson, RK Mitchell, L Marselli, TJ Pullen, S Gimeno Brias, F Semplici, ... Diabetes 63 (9), 3009-3021, 2014 | 162 | 2014 |
| Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets? N Welsh, M Cnop, I Kharroubi, M Bugliani, R Lupi, P Marchetti, DL Eizirik Diabetes 54 (11), 3238-3244, 2005 | 155 | 2005 |
| Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes M Solimena, AM Schulte, L Marselli, F Ehehalt, D Richter, M Kleeberg, ... Diabetologia 61, 641-657, 2018 | 153 | 2018 |
| Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic β cells V Dominguez, C Raimondi, S Somanath, M Bugliani, MK Loder, ... Journal of Biological Chemistry 286 (6), 4216-4225, 2011 | 153 | 2011 |
