NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals P Duewell, H Kono, KJ Rayner, CM Sirois, G Vladimer, FG Bauernfeind, ... Nature 464 (7293), 1357-1361, 2010 | 4019 | 2010 |
Somatic mutations of calreticulin in myeloproliferative neoplasms T Klampfl, H Gisslinger, AS Harutyunyan, H Nivarthi, E Rumi, JD Milosevic, ... New England Journal of Medicine 369 (25), 2379-2390, 2013 | 2374 | 2013 |
The NLRP12 inflammasome recognizes Yersinia pestis GI Vladimer, D Weng, SWM Paquette, SK Vanaja, VAK Rathinam, ... Immunity 37 (1), 96-107, 2012 | 406 | 2012 |
Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death D Weng, R Marty-Roix, S Ganesan, MK Proulx, GI Vladimer, WJ Kaiser, ... Proceedings of the National Academy of Sciences 111 (20), 7391-7396, 2014 | 317 | 2014 |
Inflammasomes and host defenses against bacterial infections GI Vladimer, R Marty-Roix, S Ghosh, D Weng, E Lien Current opinion in microbiology 16 (1), 23-31, 2013 | 207 | 2013 |
A conserved circular network of coregulated lipids modulates innate immune responses MS Köberlin, B Snijder, LX Heinz, CL Baumann, A Fauster, GI Vladimer, ... Cell 162 (1), 170-183, 2015 | 201 | 2015 |
Identification of QS-21 as an inflammasome-activating molecular component of saponin adjuvants R Marty-Roix, GI Vladimer, K Pouliot, D Weng, R Buglione-Corbett, ... Journal of Biological Chemistry 291 (3), 1123-1136, 2016 | 198 | 2016 |
Image-based ex-vivo drug screening for patients with aggressive haematological malignancies: interim results from a single-arm, open-label, pilot study B Snijder, GI Vladimer, N Krall, K Miura, AS Schmolke, C Kornauth, ... The Lancet Haematology 4 (12), e595-e606, 2017 | 172 | 2017 |
LZTR1 is a regulator of RAS ubiquitination and signaling JW Bigenzahn, GM Collu, F Kartnig, M Pieraks, GI Vladimer, LX Heinz, ... Science 362 (6419), 1171-1177, 2018 | 165 | 2018 |
Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity KL Willmann, S Klaver, F Doğu, E Santos-Valente, W Garncarz, I Bilic, ... Nature communications 5 (1), 5360, 2014 | 140 | 2014 |
Proposed diagnostic criteria for classical chronic myelomonocytic leukemia (CMML), CMML variants and pre-CMML conditions P Valent, A Orazi, MR Savona, MM Patnaik, F Onida, ... haematologica 104 (10), 1935, 2019 | 126 | 2019 |
A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling NJ Nilsen, GI Vladimer, J Stenvik, MPA Orning, MV Zeid-Kilani, M Bugge, ... Journal of Biological Chemistry 290 (6), 3209-3222, 2015 | 116 | 2015 |
IFITs: emerging roles as key anti-viral proteins GI Vladimer, MW Górna, G Superti-Furga Frontiers in immunology 5, 78627, 2014 | 113 | 2014 |
Functional precision medicine provides clinical benefit in advanced aggressive hematologic cancers and identifies exceptional responders C Kornauth, T Pemovska, GI Vladimer, G Bayer, M Bergmann, S Eder, ... Cancer discovery 12 (2), 372-387, 2022 | 96 | 2022 |
Global survey of the immunomodulatory potential of common drugs GI Vladimer, B Snijder, N Krall, JW Bigenzahn, KVM Huber, CH Lardeau, ... Nature chemical biology 13 (6), 681-690, 2017 | 66 | 2017 |
The RNA‐binding protein HuR/ELAVL1 regulates IFN‐β mRNA abundance and the type I IFN response B Herdy, T Karonitsch, GI Vladimer, CSH Tan, A Stukalov, C Trefzer, ... European journal of immunology 45 (5), 1500-1511, 2015 | 57 | 2015 |
Gadolinium-based compounds induce NLRP3-dependent IL-1β production and peritoneal inflammation C Schmidt-Lauber, L Bossaller, HH Abujudeh, GI Vladimer, A Christ, ... Annals of the rheumatic diseases 74 (11), 2062-2069, 2015 | 43 | 2015 |
Combined chemosensitivity and chromatin profiling prioritizes drug combinations in CLL C Schmidl, GI Vladimer, AF Rendeiro, S Schnabl, T Krausgruber, ... Nature chemical biology 15 (3), 232-240, 2019 | 39 | 2019 |
A time-resolved molecular map of the macrophage response to VSV infection RK Kandasamy, GI Vladimer, B Snijder, AC Müller, M Rebsamen, ... NPJ systems biology and applications 2 (1), 1-12, 2016 | 36 | 2016 |
An inducible retroviral expression system for tandem affinity purification mass-spectrometry-based proteomics identifies mixed lineage kinase domain-like protein (MLKL) as an … JW Bigenzahn, A Fauster, M Rebsamen, RK Kandasamy, S Scorzoni, ... Molecular & Cellular Proteomics 15 (3), 1139-1150, 2016 | 31 | 2016 |