Effect of gene therapy on visual function in Leber's congenital amaurosis JWB Bainbridge, AJ Smith, SS Barker, S Robbie, R Henderson, ... New England Journal of Medicine 358 (21), 2231-2239, 2008 | 2422 | 2008 |
Long-term effect of gene therapy on Leber’s congenital amaurosis JWB Bainbridge, MS Mehat, V Sundaram, SJ Robbie, SE Barker, ... New England Journal of Medicine 372 (20), 1887-1897, 2015 | 799 | 2015 |
Restoration of vision after transplantation of photoreceptors RA Pearson, AC Barber, M Rizzi, C Hippert, T Xue, EL West, Y Duran, ... Nature 485 (7396), 99-103, 2012 | 563 | 2012 |
LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling X Wang, S Abraham, JAG McKenzie, N Jeffs, M Swire, VB Tripathi, ... Nature 499 (7458), 306-311, 2013 | 517 | 2013 |
Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina A Gonzalez-Cordero, EL West, RA Pearson, Y Duran, LS Carvalho, ... Nature biotechnology 31 (8), 741-747, 2013 | 449 | 2013 |
Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy RR Ali, GM Sarra, C Stephens, M Alwis, JWB Bainbridge, PM Munro, ... Nature genetics 25 (3), 306-310, 2000 | 403 | 2000 |
Clinical efficacy of intravitreal aflibercept versus panretinal photocoagulation for best corrected visual acuity in patients with proliferative diabetic retinopathy at 52 … S Sivaprasad, AT Prevost, JC Vasconcelos, A Riddell, C Murphy, J Kelly, ... The Lancet 389 (10085), 2193-2203, 2017 | 400 | 2017 |
Repair of the degenerate retina by photoreceptor transplantation AC Barber, C Hippert, Y Duran, EL West, JWB Bainbridge, ... Proceedings of the National Academy of Sciences 110 (1), 354-359, 2013 | 327 | 2013 |
The drusenlike phenotype in aging Ccl2-knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages UFO Luhmann, S Robbie, PMG Munro, SE Barker, Y Duran, V Luong, ... Investigative ophthalmology & visual science 50 (12), 5934-5943, 2009 | 255 | 2009 |
In vivo gene transfer to the mouse eye using an HIV-based lentiviral vector; efficient long-term transduction of corneal endothelium and retinal pigment epithelium JWB Bainbridge, C Stephens, K Parsley, C Demaison, A Halfyard, ... Gene therapy 8 (21), 1665-1668, 2001 | 241 | 2001 |
Transplantation of human embryonic stem cell-derived retinal pigment epithelial cells in macular degeneration MS Mehat, V Sundaram, C Ripamonti, AG Robson, AJ Smith, S Borooah, ... Ophthalmology 125 (11), 1765-1775, 2018 | 233 | 2018 |
Recapitulation of human retinal development from human pluripotent stem cells generates transplantable populations of cone photoreceptors A Gonzalez-Cordero, K Kruczek, A Naeem, M Fernando, M Kloc, J Ribeiro, ... Stem cell reports 9 (3), 820-837, 2017 | 233 | 2017 |
Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1 JWB Bainbridge, A Mistry, M De Alwis, E Paleolog, A Baker, AJ Thrasher, ... Gene therapy 9 (5), 320-326, 2002 | 222 | 2002 |
Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy LS Carvalho, J Xu, RA Pearson, AJ Smith, JW Bainbridge, LM Morris, ... Human molecular genetics 20 (16), 3161-3175, 2011 | 202 | 2011 |
Retinal structure and function in achromatopsia: implications for gene therapy V Sundaram, C Wilde, J Aboshiha, J Cowing, C Han, CS Langlo, ... Ophthalmology 121 (1), 234-245, 2014 | 187 | 2014 |
Gene replacement therapy in the retinal degeneration slow (rds) mouse: the effect on retinal degeneration following partial transduction of the retina GM Sarra, C Stephens, M De Alwis, JWB Bainbridge, AJ Smith, ... Human molecular genetics 10 (21), 2353-2361, 2001 | 185 | 2001 |
Gene therapy progress and prospects: the eye JWB Bainbridge, MH Tan, RR Ali Gene therapy 13 (16), 1191-1197, 2006 | 181 | 2006 |
Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy M Tschernutter, FC Schlichtenbrede, S Howe, KS Balaggan, PM Munro, ... Gene therapy 12 (8), 694-701, 2005 | 174 | 2005 |
AAV-Mediated gene transfer slows photoreceptor loss in the RCS rat model of retinitis pigmentosa AJ Smith, FC Schlichtenbrede, M Tschernutter, JW Bainbridge, ... Molecular therapy 8 (2), 188-195, 2003 | 172 | 2003 |
Gene therapy for retinitis pigmentosa and Leber congenital amaurosis caused by defects in AIPL1: effective rescue of mouse models of partial and complete Aipl1 … MH Tan, AJ Smith, B Pawlyk, X Xu, X Liu, JB Bainbridge, M Basche, ... Human molecular genetics 18 (12), 2099-2114, 2009 | 161 | 2009 |