A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity TM Frayling, NJ Timpson, MN Weedon, E Zeggini, RM Freathy, ... Science 316 (5826), 889-894, 2007 | 5641 | 2007 |
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes E Zeggini, MN Weedon, CM Lindgren, TM Frayling, KS Elliott, H Lango, ... Science 316 (5829), 1336-1341, 2007 | 2619 | 2007 |
Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer. LW Harries, MJ Stubbins, D Forman, GC Howard, CR Wolf Carcinogenesis 18 (4), 641-644, 1997 | 970 | 1997 |
Genotypes of glutathione transferase M1 and P1 and their significance for lung DNA adduct levels and cancer risk. D Ryberg, V Skaug, A Hewer, DH Phillips, LW Harries, CR Wolf, D Ogreid, ... Carcinogenesis 18 (7), 1285-1289, 1997 | 573 | 1997 |
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease K Lunnon, R Smith, E Hannon, PL De Jager, G Srivastava, M Volta, ... Nature neuroscience 17 (9), 1164-1170, 2014 | 557 | 2014 |
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes LW Harries, AT Hattersley, ASF Doney, H Colhoun, AD Morris, ... Nature genetics 43 (2), 117-120, 2011 | 498 | 2011 |
Genetic analysis of the human cytochrome P450 CYP2C9 locus MJ Stubbins, LW Harries, G Smith, MH Tarbit, CR Wolf Pharmacogenetics and Genomics 6 (5), 429-439, 1996 | 400 | 1996 |
Long non-coding RNAs and human disease LW Harries Biochemical Society Transactions 40 (4), 902-906, 2012 | 310 | 2012 |
Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing LW Harries, D Hernandez, W Henley, AR Wood, AC Holly, ... Aging cell 10 (5), 868-878, 2011 | 307 | 2011 |
Update of mutations in the genes encoding the pancreatic beta‐cell KATP channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes … SE Flanagan, S Clauin, C Bellanné‐Chantelot, P de Lonlay, LW Harries, ... Human mutation 30 (2), 170-180, 2009 | 297 | 2009 |
HNF1B mutations associate with hypomagnesemia and renal magnesium wasting S Adalat, AS Woolf, KA Johnstone, A Wirsing, LW Harries, DA Long, ... Journal of the American Society of Nephrology 20 (5), 1123-1131, 2009 | 273 | 2009 |
Circular RNAs (circRNAs) in health and disease S Haque, LW Harries Genes 8 (12), 353, 2017 | 247 | 2017 |
Permanent neonatal diabetes caused by dominant, recessive, or compound heterozygous SUR1 mutations with opposite functional effects S Ellard, SE Flanagan, CA Girard, AM Patch, LW Harries, A Parrish, ... The American Journal of Human Genetics 81 (2), 375-382, 2007 | 246 | 2007 |
Wellcome Trust Case Control Consortium (WTCCC), McCarthy MI, Hattersley AT: Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes E Zeggini, MN Weedon, CM Lindgren, TM Frayling, KS Elliott, H Lango, ... Science 316 (5829), 1336-1341, 2007 | 235 | 2007 |
Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis I Garin, EL Edghill, I Akerman, O Rubio-Cabezas, I Rica, JM Locke, ... Proceedings of the National Academy of Sciences 107 (7), 3105-3110, 2010 | 220 | 2010 |
Molecular genetics of the human cytochrome P450 monooxygenase superfamily G Smith, MJ Stubbins, LW Harries, CR Wolf Xenobiotica 28 (12), 1129-1165, 1998 | 212 | 1998 |
Human longevity: 25 genetic loci associated in 389,166 UK biobank participants LC Pilling, CL Kuo, K Sicinski, J Tamosauskaite, GA Kuchel, LW Harries, ... Aging (Albany NY) 9 (12), 2504, 2017 | 183 | 2017 |
Associations between PFOA, PFOS and changes in the expression of genes involved in cholesterol metabolism in humans T Fletcher, TS Galloway, D Melzer, P Holcroft, R Cipelli, LC Pilling, ... Environment international 57, 2-10, 2013 | 182 | 2013 |
Isomers of the TCF1 gene encoding hepatocyte nuclear factor-1 alpha show differential expression in the pancreas and define the relationship … LW Harries, S Ellard, A Stride, NG Morgan, AT Hattersley Human molecular genetics 15 (14), 2216-2224, 2006 | 175 | 2006 |
The glutathione S-transferase GSTP1 polymorphism: effects on susceptibility to oral/pharyngeal and laryngeal carcinomas C Matthias, U Bockmühl, V Jahnke, LW Harries, CR Wolf, PW Jones, ... Pharmacogenetics and Genomics 8 (1), 1-6, 1998 | 156 | 1998 |