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Lorna Harries
Lorna Harries
University of Exeter Medical School
在 exeter.ac.uk 的电子邮件经过验证 - 首页
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A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
TM Frayling, NJ Timpson, MN Weedon, E Zeggini, RM Freathy, ...
Science 316 (5826), 889-894, 2007
56412007
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
E Zeggini, MN Weedon, CM Lindgren, TM Frayling, KS Elliott, H Lango, ...
Science 316 (5829), 1336-1341, 2007
26192007
Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer.
LW Harries, MJ Stubbins, D Forman, GC Howard, CR Wolf
Carcinogenesis 18 (4), 641-644, 1997
9701997
Genotypes of glutathione transferase M1 and P1 and their significance for lung DNA adduct levels and cancer risk.
D Ryberg, V Skaug, A Hewer, DH Phillips, LW Harries, CR Wolf, D Ogreid, ...
Carcinogenesis 18 (7), 1285-1289, 1997
5731997
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease
K Lunnon, R Smith, E Hannon, PL De Jager, G Srivastava, M Volta, ...
Nature neuroscience 17 (9), 1164-1170, 2014
5572014
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes
LW Harries, AT Hattersley, ASF Doney, H Colhoun, AD Morris, ...
Nature genetics 43 (2), 117-120, 2011
4982011
Genetic analysis of the human cytochrome P450 CYP2C9 locus
MJ Stubbins, LW Harries, G Smith, MH Tarbit, CR Wolf
Pharmacogenetics and Genomics 6 (5), 429-439, 1996
4001996
Long non-coding RNAs and human disease
LW Harries
Biochemical Society Transactions 40 (4), 902-906, 2012
3102012
Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing
LW Harries, D Hernandez, W Henley, AR Wood, AC Holly, ...
Aging cell 10 (5), 868-878, 2011
3072011
Update of mutations in the genes encoding the pancreatic beta‐cell KATP channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes …
SE Flanagan, S Clauin, C Bellanné‐Chantelot, P de Lonlay, LW Harries, ...
Human mutation 30 (2), 170-180, 2009
2972009
HNF1B mutations associate with hypomagnesemia and renal magnesium wasting
S Adalat, AS Woolf, KA Johnstone, A Wirsing, LW Harries, DA Long, ...
Journal of the American Society of Nephrology 20 (5), 1123-1131, 2009
2732009
Circular RNAs (circRNAs) in health and disease
S Haque, LW Harries
Genes 8 (12), 353, 2017
2472017
Permanent neonatal diabetes caused by dominant, recessive, or compound heterozygous SUR1 mutations with opposite functional effects
S Ellard, SE Flanagan, CA Girard, AM Patch, LW Harries, A Parrish, ...
The American Journal of Human Genetics 81 (2), 375-382, 2007
2462007
Wellcome Trust Case Control Consortium (WTCCC), McCarthy MI, Hattersley AT: Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
E Zeggini, MN Weedon, CM Lindgren, TM Frayling, KS Elliott, H Lango, ...
Science 316 (5829), 1336-1341, 2007
2352007
Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis
I Garin, EL Edghill, I Akerman, O Rubio-Cabezas, I Rica, JM Locke, ...
Proceedings of the National Academy of Sciences 107 (7), 3105-3110, 2010
2202010
Molecular genetics of the human cytochrome P450 monooxygenase superfamily
G Smith, MJ Stubbins, LW Harries, CR Wolf
Xenobiotica 28 (12), 1129-1165, 1998
2121998
Human longevity: 25 genetic loci associated in 389,166 UK biobank participants
LC Pilling, CL Kuo, K Sicinski, J Tamosauskaite, GA Kuchel, LW Harries, ...
Aging (Albany NY) 9 (12), 2504, 2017
1832017
Associations between PFOA, PFOS and changes in the expression of genes involved in cholesterol metabolism in humans
T Fletcher, TS Galloway, D Melzer, P Holcroft, R Cipelli, LC Pilling, ...
Environment international 57, 2-10, 2013
1822013
Isomers of the TCF1 gene encoding hepatocyte nuclear factor-1 alpha show differential expression in the pancreas and define the relationship …
LW Harries, S Ellard, A Stride, NG Morgan, AT Hattersley
Human molecular genetics 15 (14), 2216-2224, 2006
1752006
The glutathione S-transferase GSTP1 polymorphism: effects on susceptibility to oral/pharyngeal and laryngeal carcinomas
C Matthias, U Bockmühl, V Jahnke, LW Harries, CR Wolf, PW Jones, ...
Pharmacogenetics and Genomics 8 (1), 1-6, 1998
1561998
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