Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe−/− and Ldlr−/− mice lacking CHOP E Thorp, G Li, TA Seimon, G Kuriakose, D Ron, I Tabas Cell metabolism 9 (5), 474-481, 2009 | 399 | 2009 |
Mertk receptor mutation reduces efferocytosis efficiency and promotes apoptotic cell accumulation and plaque necrosis in atherosclerotic lesions of apoe−/− mice E Thorp, D Cui, DM Schrijvers, G Kuriakose, I Tabas Arteriosclerosis, thrombosis, and vascular biology 28 (8), 1421-1428, 2008 | 383 | 2008 |
Therapeutic inflammatory monocyte modulation using immune-modifying microparticles DR Getts, RL Terry, MT Getts, C Deffrasnes, M Müller, C van Vreden, ... Science translational medicine 6 (219), 219ra7-219ra7, 2014 | 376 | 2014 |
Enhanced efferocytosis of apoptotic cardiomyocytes through myeloid-epithelial-reproductive tyrosine kinase links acute inflammation resolution to cardiac repair after infarction E Wan, XY Yeap, S Dehn, R Terry, M Novak, S Zhang, S Iwata, X Han, ... Circulation research 113 (8), 1004-1012, 2013 | 330 | 2013 |
Efferocytosis fuels requirements of fatty acid oxidation and the electron transport chain to polarize macrophages for tissue repair S Zhang, S Weinberg, M DeBerge, A Gainullina, M Schipma, JM Kinchen, ... Cell metabolism 29 (2), 443-456. e5, 2019 | 291 | 2019 |
Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated … E Thorp, T Vaisar, M Subramanian, L Mautner, C Blobel, I Tabas Journal of Biological Chemistry 286 (38), 33335-33344, 2011 | 280 | 2011 |
Mechanisms and consequences of efferocytosis in advanced atherosclerosis E Thorp, I Tabas Journal of leukocyte biology 86 (5), 1089-1095, 2009 | 258 | 2009 |
ABCA1 and ABCG1 protect against oxidative stress–induced macrophage apoptosis during efferocytosis L Yvan-Charvet, TA Pagler, TA Seimon, E Thorp, CL Welch, JL Witztum, ... Circulation research 106 (12), 1861-1869, 2010 | 216 | 2010 |
Toll‐like receptor‐mediated IRE1α activation as a therapeutic target for inflammatory arthritis Q Qiu, Z Zheng, L Chang, YS Zhao, C Tan, A Dandekar, Z Zhang, Z Lin, ... The EMBO journal 32 (18), 2477-2490, 2013 | 207 | 2013 |
MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis B Cai, EB Thorp, AC Doran, BE Sansbury, MJAP Daemen, B Dorweiler, ... The Journal of clinical investigation 127 (2), 564-568, 2017 | 202 | 2017 |
Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs M Subramanian, E Thorp, GK Hansson, I Tabas The Journal of clinical investigation 123 (1), 179-188, 2013 | 202 | 2013 |
MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation B Cai, EB Thorp, AC Doran, M Subramanian, BE Sansbury, CS Lin, ... Proceedings of the National Academy of Sciences 113 (23), 6526-6531, 2016 | 187 | 2016 |
Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice D Ai, C Chen, S Han, A Ganda, AJ Murphy, R Haeusler, E Thorp, D Accili, ... The Journal of clinical investigation 122 (4), 2012 | 185 | 2012 |
MerTK cleavage on resident cardiac macrophages compromises repair after myocardial ischemia reperfusion injury M DeBerge, XY Yeap, S Dehn, S Zhang, L Grigoryeva, S Misener, ... Circulation research 121 (8), 930-940, 2017 | 180 | 2017 |
Cytomegalovirus latency and reactivation: an intricate interplay with the host immune response E Forte, Z Zhang, EB Thorp, M Hummel Frontiers in cellular and infection microbiology 10, 130, 2020 | 173 | 2020 |
Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet S Li, Y Sun, CP Liang, EB Thorp, S Han, AW Jehle, V Saraswathi, ... Circulation research 105 (11), 1072-1082, 2009 | 166 | 2009 |
Requirements for CEACAMs and cholesterol during murine coronavirus cell entry EB Thorp, TM Gallagher Journal of virology 78 (6), 2682-2692, 2004 | 140 | 2004 |
The role of macrophages and dendritic cells in the clearance of apoptotic cells in advanced atherosclerosis E Thorp, M Subramanian, I Tabas European journal of immunology 41 (9), 2515-2518, 2011 | 134 | 2011 |
Lymphoangiocrine signals promote cardiac growth and repair X Liu, E De la Cruz, X Gu, L Balint, M Oxendine-Burns, T Terrones, W Ma, ... Nature 588 (7839), 705-711, 2020 | 131 | 2020 |
Brief Report: Increased Apoptosis in Advanced Atherosclerotic Lesions of Apoe−/− Mice Lacking Macrophage Bcl-2 E Thorp, Y Li, L Bao, PM Yao, G Kuriakose, J Rong, EA Fisher, I Tabas Arteriosclerosis, thrombosis, and vascular biology 29 (2), 169-172, 2009 | 124 | 2009 |