Dynamic combinatorial selection of molecules capable of inhibiting the (CUG) repeat RNA− MBNL1 interaction in vitro: discovery of lead compounds targeting myotonic dystrophy (DM1) PC Gareiss, K Sobczak, BR McNaughton, PB Palde, CA Thornton, ... Journal of the American Chemical Society 130 (48), 16254-16261, 2008 | 221 | 2008 |
Safe and efficient tetrazole synthesis in a continuous‐flow microreactor PB Palde, TF Jamison Angewandte Chemie 123 (15), 3587-3590, 2011 | 136 | 2011 |
Molecular basis for redox activation of epidermal growth factor receptor kinase TH Truong, PMU Ung, PB Palde, CE Paulsen, A Schlessinger, KS Carroll Cell chemical biology 23 (7), 837-848, 2016 | 114 | 2016 |
Substituted 4-methylquinolines as a new class of anti-tuberculosis agents R Jain, B Vaitilingam, A Nayyar, PB Palde Bioorganic & medicinal chemistry letters 13 (6), 1051-1054, 2003 | 92 | 2003 |
Ring-substituted quinolines. Part 2: Synthesis and antimycobacterial activities of ring-substituted quinolinecarbohydrazide and ring-substituted quinolinecarboxamide analogues V Monga, A Nayyar, B Vaitilingam, PB Palde, SS Jhamb, S Kaur, ... Bioorganic & medicinal chemistry 12 (24), 6465-6472, 2004 | 75 | 2004 |
Synthesis and antimycobacterial activities of ring-substituted quinolinecarboxylic acid/ester analogues. Part 1 B Vaitilingam, A Nayyar, PB Palde, V Monga, R Jain, S Kaur, PP Singh Bioorganic & medicinal chemistry 12 (15), 4179-4188, 2004 | 64 | 2004 |
A universal entropy-driven mechanism for thioredoxin–target recognition PB Palde, KS Carroll Proceedings of the National Academy of Sciences 112 (26), 7960-7965, 2015 | 60 | 2015 |
First-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosis PB Palde, A Bhaskar, LE Pedró Rosa, F Madoux, P Chase, V Gupta, ... ACS chemical biology 11 (1), 172-184, 2016 | 43 | 2016 |
Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1 K Ryan, B Bolaňos, M Smith, PB Palde, PD Cuenca, TL VanArsdale, ... Journal of Biological Chemistry 296, 2021 | 42 | 2021 |
Selective recognition of alkyl pyranosides in protic and aprotic solvents PB Palde, PC Gareiss, BL Miller Journal of the American Chemical Society 130 (29), 9566-9573, 2008 | 42 | 2008 |
Strategies for Recognition of Stem− Loop RNA Structures by Synthetic Ligands: Application to the HIV-1 Frameshift Stimulatory Sequence PB Palde, LO Ofori, PC Gareiss, J Lerea, BL Miller Journal of medicinal chemistry 53 (16), 6018-6027, 2010 | 40 | 2010 |
SAM-competitive PRMT5 inhibitor PF-06939999 demonstrates antitumor activity in splicing dysregulated NSCLC with decreased liability of drug resistance K Jensen-Pergakes, J Tatlock, KA Maegley, IJ McAlpine, M McTigue, ... Molecular Cancer Therapeutics 21 (1), 3-15, 2022 | 35 | 2022 |
A metal-free approach for brønsted acid promoted C–H alkylation of heteroarenes with alkyl peroxides Y Zeng, B Qian, Y Li, H Bao Synthesis 50 (16), 3250-3256, 2018 | 11 | 2018 |
Single-step synthesis of functional organic receptors via a tridirectional minisci reaction PB Palde, BR McNaughton, NT Ross, PC Gareiss, CR Mace, RC Spitale, ... Synthesis 2007 (15), 2287-2290, 2007 | 6 | 2007 |
Conformational and Structural Analysis of a ter‐Cyclopentane Scaffold for Molecular Recognition PC Gareiss, PB Palde, RD Hubbard, BL Miller European journal of organic chemistry 2007 (1), 53-61, 2007 | 4 | 2007 |
Use of azides in synthesis TF Jamison, PB Palde US Patent App. 13/817,291, 2013 | 2 | 2013 |
Functional Site Discovery in a Sulfur Metabolism Enzyme by Using Directed Evolution H Paritala, PB Palde, KS Carroll ChemBioChem 17 (19), 1873-1878, 2016 | | 2016 |
Tripodal cyclohexane derivatives and their use as carbohydrate receptors BL Miller, PB Palde, PC Gareiss US Patent 8,716,472, 2014 | | 2014 |
Exploring small molecules as receptors in carbohydrate recognition and as ligands targeting RNA sequences relevant to HIV-1 PB Palde University of Rochester, 2009 | | 2009 |
Corrigendum to “Ring-substituted quinolines. Part 2: Synthesis and antimycobacterial activities of ring-substituted quinolinecarbohydrazide and ring-substituted … V Monga, A Nayyar, B Vaitilingam, PB Palde, SS Jhamb, S Kaur, ... Bioorganic & Medicinal Chemistry 5 (13), 1879, 2005 | | 2005 |