Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness S Khare, AS Nagle, A Biggart, YH Lai, F Liang, LC Davis, SW Barnes, ... Nature 537 (7619), 229-233, 2016 | 402 | 2016 |
A protective and agonistic function of IL-12p40 in mycobacterial infection C Hölscher, RA Atkinson, B Arendse, N Brown, E Myburgh, G Alber, ... The Journal of Immunology 167 (12), 6957-6966, 2001 | 309 | 2001 |
Impairment of alternative macrophage activation delays cutaneous leishmaniasis in nonhealing BALB/c mice C Hölscher, B Arendse, A Schwegmann, E Myburgh, F Brombacher The Journal of Immunology 176 (2), 1115-1121, 2006 | 144 | 2006 |
IL-4-induced GATA-3 expression is a time-restricted instruction switch for Th2 cell differentiation N Seki, M Miyazaki, W Suzuki, K Hayashi, K Arima, E Myburgh, K Izuhara, ... The Journal of Immunology 172 (10), 6158-6166, 2004 | 132 | 2004 |
Where are we? The anatomy of the murine cortical meninges revisited for intravital imaging, immunology, and clearance of waste from the brain JA Coles, E Myburgh, JM Brewer, PG McMenamin Progress in neurobiology 156, 107-148, 2017 | 121 | 2017 |
Delayed goblet cell hyperplasia, acetylcholine receptor expression, and worm expulsion in SMC-specific IL-4Rα–deficient mice WGC Horsnell, AJ Cutler, CJ Hoving, H Mearns, E Myburgh, B Arendse, ... PLoS pathogens 3 (1), e1, 2007 | 98 | 2007 |
Highly sensitive in vivo imaging of Trypanosoma brucei expressing “red-shifted” luciferase AP McLatchie, H Burrell-Saward, E Myburgh, MD Lewis, TH Ward, ... PLoS neglected tropical diseases 7 (11), e2571, 2013 | 79 | 2013 |
In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis E Myburgh, JA Coles, R Ritchie, PGE Kennedy, AP McLatchie, J Rodgers, ... PLoS neglected tropical diseases 7 (8), e2384, 2013 | 75 | 2013 |
Conditional gene deletion with DiCre demonstrates an essential role for CRK3 in Leishmania mexicana cell cycle regulation SM Duncan, E Myburgh, C Philipon, E Brown, M Meissner, J Brewer, ... Molecular microbiology 100 (6), 931-944, 2016 | 67 | 2016 |
Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors M Saldivia, E Fang, X Ma, E Myburgh, JBT Carnielli, C Bower-Lepts, ... Nature Microbiology, 1-10, 2020 | 50 | 2020 |
IL-4Rα-responsive smooth muscle cells contribute to initiation of TH2 immunity and pulmonary pathology in Nippostrongylus brasiliensis infections WGC Horsnell, A Vira, F Kirstein, H Mearns, JC Hoving, AJ Cutler, ... Mucosal immunology 4 (1), 83-92, 2010 | 41 | 2010 |
Intravital imaging of a massive lymphocyte response in the cortical dura of mice after peripheral infection by trypanosomes JA Coles, E Myburgh, R Ritchie, A Hamilton, J Rodgers, JC Mottram, ... PLoS neglected tropical diseases 9 (4), e0003714, 2015 | 38 | 2015 |
Interleukin-4-promoted T helper 2 responses enhance Nippostrongylus brasiliensis-induced pulmonary pathology H Mearns, WGC Horsnell, JC Hoving, B Dewals, AJ Cutler, F Kirstein, ... Infection and immunity 76 (12), 5535-5542, 2008 | 36 | 2008 |
The mouse cortical meninges are the site of immune responses to many different pathogens, and are accessible to intravital imaging JA Coles, PJ Stewart-Hutchinson, E Myburgh, JM Brewer Methods 127, 53-61, 2017 | 35 | 2017 |
TLR2 Signaling in Skin Nonhematopoietic Cells Induces Early Neutrophil Recruitment in Response to Leishmania major Infection C Ronet, K Passelli, M Charmoy, L Scarpellino, E Myburgh, YH La Torre, ... Journal of Investigative Dermatology 139 (6), 1318-1328, 2019 | 27 | 2019 |
Imaging of the host/parasite interplay in cutaneous leishmaniasis OR Millington, E Myburgh, JC Mottram, J Alexander Experimental parasitology 126 (3), 310-317, 2010 | 25 | 2010 |
Imaging African trypanosomes L MacLean, E Myburgh, J Rodgers, HP Price Parasite immunology 35 (9-10), 283-294, 2013 | 24 | 2013 |
Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice IW McNae, J Kinkead, D Malik, LH Yen, MK Walker, C Swain, SP Webster, ... Nature Communications 12 (1), 1-10, 2021 | 23 | 2021 |
Inhibitor of serine peptidase 2 enhances Leishmania major survival in the skin through control of monocytes and monocyte-derived cells A Goundry, A Romano, APCA Lima, JC Mottram, E Myburgh The FASEB Journal 32 (3), 1315-1327, 2017 | 15 | 2017 |
PNT1 is a C11 cysteine peptidase essential for replication of the Trypanosome kinetoplast JS Grewal, K McLuskey, D Das, E Myburgh, J Wilkes, E Brown, ... Journal of Biological Chemistry 291 (18), 9492-9500, 2016 | 15 | 2016 |