Attenuation of c GAS‐STING signaling is mediated by a p62/SQSTM 1‐dependent autophagy pathway activated by TBK1 T Prabakaran, C Bodda, C Krapp, B Zhang, MH Christensen, C Sun, ... The EMBO journal 37 (8), e97858, 2018 | 373 | 2018 |
IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP KL Jønsson, A Laustsen, C Krapp, KA Skipper, K Thavachelvam, D Hotter, ... Nature communications 8 (1), 14391, 2017 | 298 | 2017 |
Listeria monocytogenes induces IFNβ expression through an IFI16‐, cGAS‐ and STING‐dependent pathway K Hansen, T Prabakaran, A Laustsen, SE Jørgensen, SH Rahbæk, ... The EMBO journal 33 (15), 1654-1666, 2014 | 279 | 2014 |
HSV‐1 ICP 27 targets the TBK 1‐activated STING signalsome to inhibit virus‐induced type I IFN expression MH Christensen, SB Jensen, JJ Miettinen, S Luecke, T Prabakaran, ... The EMBO journal 35 (13), 1385-1399, 2016 | 215 | 2016 |
Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections B Ogunjimi, SY Zhang, KB Sørensen, KA Skipper, M Carter-Timofte, ... The Journal of clinical investigation 127 (9), 3543-3556, 2017 | 137 | 2017 |
Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease T Prabakaran, R Nielsen, JV Larsen, SS Sørensen, UF Rasmussen, ... PloS one 6 (9), e25065, 2011 | 137 | 2011 |
Intracellular bacteria engage a STING–TBK1–MVB12b pathway to enable paracrine cGAS–STING signalling R Nandakumar, R Tschismarov, F Meissner, T Prabakaran, ... Nature microbiology 4 (4), 701-713, 2019 | 120 | 2019 |
STEEP mediates STING ER exit and activation of signaling B Zhang, R Nandakumar, LS Reinert, J Huang, A Laustsen, Z Gao, C Sun, ... Nature immunology 21 (8), 868-879, 2020 | 107 | 2020 |
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking SC Klinger, S Glerup, MK Raarup, MC Mari, M Nyegaard, G Koster, ... Journal of cell science 124 (7), 1095-1105, 2011 | 92 | 2011 |
An innate antiviral pathway acting before interferons at epithelial surfaces MB Iversen, LS Reinert, MK Thomsen, I Bagdonaite, R Nandakumar, ... Nature immunology 17 (2), 150-158, 2016 | 83 | 2016 |
STING mediates lupus via the activation of conventional dendritic cell maturation and plasmacytoid dendritic cell differentiation A Thim-Uam, T Prabakaran, M Tansakul, J Makjaroen, ... Iscience 23 (9), 2020 | 67 | 2020 |
Cubilin is expressed in rat and human glomerular podocytes T Prabakaran, EI Christensen, R Nielsen, PJ Verroust Nephrology Dialysis Transplantation 27 (8), 3156-3159, 2012 | 65 | 2012 |
A STING antagonist modulating the interaction with STIM1 blocks ER-to-Golgi trafficking and inhibits lupus pathology T Prabakaran, A Troldborg, S Kumpunya, I Alee, E Marinković, ... EBioMedicine 66, 2021 | 49 | 2021 |
Long-term enzyme replacement therapy is associated with reduced proteinuria and preserved proximal tubular function in women with Fabry disease T Prabakaran, H Birn, BM Bibby, A Regeniter, SS Sørensen, ... Nephrology Dialysis Transplantation 29 (3), 619-625, 2014 | 48 | 2014 |
Mannose 6-phosphate receptor and sortilin mediated endocytosis of α-galactosidase A in kidney endothelial cells T Prabakaran, R Nielsen, SC Satchell, PW Mathieson, ... PloS one 7 (6), e39975, 2012 | 44 | 2012 |
Identification of Alzheimer disease risk genotype that predicts efficiency of SORL1 expression in the brain S Caglayan, A Bauerfeind, V Schmidt, AS Carlo, T Prabakaran, N Hübner, ... Archives of neurology 69 (3), 373-379, 2012 | 41 | 2012 |
Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation J Guerra, AL Valadao, D Vlachakis, K Polak, IK Vila, C Taffoni, ... Science advances 6 (21), eaax3333, 2020 | 32 | 2020 |
Human sorCS1 binds sortilin and hampers its cellular functions JV Larsen, G Hermey, ES Sørensen, T Prabakaran, EI Christensen, ... Biochemical Journal 457 (2), 277-288, 2014 | 16 | 2014 |
STEEP mediates STING ER exit and activation of signaling (vol 21, pg 868, 2020) B Zhang, R Nandakumar, LS Reinert, J Huang, A Laustsen, Z Gao, C Sun, ... Nature immunology 21 (11), 1468-1469, 2020 | 3 | 2020 |
Inhibition of Sting rescues lupus disease by the regulation of Lyn-mediated dendritic cell differentiation A Thim-uam, T Prabakaran, M Tansakul, J Makjaroen, ... bioRxiv, 810192, 2019 | 2 | 2019 |