PEBP1 wardens ferroptosis by enabling lipoxygenase generation of lipid death signals SE Wenzel, YY Tyurina, J Zhao, CMS Croix, HH Dar, G Mao, VA Tyurin, ... Cell 171 (3), 628-641. e26, 2017 | 723 | 2017 |
Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing MR Macbeth, HL Schubert, AP VanDemark, AT Lingam, CP Hill, BL Bass Science 309 (5740), 1534-1539, 2005 | 500 | 2005 |
Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer AP VanDemark, RM Hofmann, C Tsui, CM Pickart, C Wolberger Cell 105 (6), 711-720, 2001 | 369 | 2001 |
Potent D-peptide inhibitors of HIV-1 entry BD Welch, AP VanDemark, A Heroux, CP Hill, MS Kay Proceedings of the National Academy of Sciences 104 (43), 16828-16833, 2007 | 333 | 2007 |
The structure of the yFACT Pob3-M domain, its interaction with the DNA replication factor RPA, and a potential role in nucleosome deposition AP VanDemark, M Blanksma, E Ferris, A Heroux, CP Hill, T Formosa Molecular cell 22 (3), 363-374, 2006 | 176 | 2006 |
Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation AP VanDemark, MM Kasten, E Ferris, A Heroux, CP Hill, BR Cairns Molecular cell 27 (5), 817-828, 2007 | 165 | 2007 |
Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin AD Wier, MK Mayekar, A Héroux, KM Arndt, AP VanDemark Proceedings of the National Academy of Sciences 110 (43), 17290-17295, 2013 | 111 | 2013 |
The histone modification domain of Paf1 complex subunit Rtf1 directly stimulates H2B ubiquitylation through an interaction with Rad6 SB Van Oss, MK Shirra, AR Bataille, AD Wier, K Yen, V Vinayachandran, ... Molecular cell 64 (4), 815-825, 2016 | 110 | 2016 |
Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits AP VanDemark, H Xin, L McCullough, R Rawlins, S Bentley, A Heroux, ... Journal of Biological Chemistry 283 (8), 5058-5068, 2008 | 107 | 2008 |
Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis TS Anthonymuthu, YY Tyurina, WY Sun, K Mikulska-Ruminska, ... Redox Biology 38, 101744, 2021 | 93 | 2021 |
Structural basis of ubiquitylation AP VanDemark, CP Hill Current opinion in structural biology 12 (6), 822-830, 2002 | 90 | 2002 |
Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52 WA Gaines, SK Godin, FF Kabbinavar, T Rao, AP VanDemark, P Sung, ... Nature communications 6 (1), 7834, 2015 | 86 | 2015 |
Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE TS Anthonymuthu, EM Kenny, I Shrivastava, YY Tyurina, ZE Hier, HC Ting, ... Journal of the American Chemical Society 140 (51), 17835-17839, 2018 | 74 | 2018 |
The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55–Rad57 to mediate error-free recombination S Godin, A Wier, F Kabbinavar, DS Bratton-Palmer, H Ghodke, ... Nucleic acids research 41 (8), 4525-4534, 2013 | 73 | 2013 |
Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin CG Amrich, CP Davis, WP Rogal, MK Shirra, A Heroux, RG Gardner, ... Journal of Biological Chemistry 287 (14), 10863-10875, 2012 | 70 | 2012 |
A novel Drosophila SOD2 mutant demonstrates a role for mitochondrial ROS in neurodevelopment and disease AM Celotto, Z Liu, AP VanDemark, MJ Palladino Brain and behavior 2 (4), 424-434, 2012 | 66 | 2012 |
Mechanisms of endothelial cell dysfunction in cystic fibrosis L Totani, R Plebani, A Piccoli, S Di Silvestre, P Lanuti, A Recchiuti, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (12 …, 2017 | 62 | 2017 |
Characterization of the N-terminal Domain of the Yeast Transcriptional Repressor Tup1: PROPOSAL FOR AN ASSOCIATION MODEL OF THE REPRESSOR COMPLEX Tup1· Ssn6 C Jabet, ER Sprague, AP VanDemark, C Wolberger Journal of Biological Chemistry 275 (12), 9011-9018, 2000 | 62 | 2000 |
Opening doors into the proteasome CM Pickart, AP VanDemark nature structural biology 7 (11), 999-1001, 2000 | 55 | 2000 |
Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase KG Hicks, AA Cluntun, HL Schubert, SR Hackett, JA Berg, PG Leonard, ... Science 379 (6636), 996-1003, 2023 | 51 | 2023 |