关注
Antoine Simoneau
Antoine Simoneau
Tango Therapeutics
在 tangotx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells
S Tirman, A Quinet, M Wood, A Meroni, E Cybulla, J Jackson, S Pegoraro, ...
Molecular cell 81 (19), 4026-4040. e8, 2021
1092021
cGAS suppresses genomic instability as a decelerator of replication forks
H Chen, H Chen, J Zhang, Y Wang, A Simoneau, H Yang, AS Levine, ...
Science advances 6 (42), eabb8941, 2020
882020
The trans cell cycle effects of PARP inhibitors underlie their selectivity toward BRCA1/2-deficient cells
A Simoneau, R Xiong, L Zou
Genes & Development 35 (17-18), 1271-1289, 2021
582021
TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R-to D-loop switch
T Yadav, JM Zhang, J Ouyang, W Leung, A Simoneau, L Zou
Molecular cell 82 (21), 3985-4000. e4, 2022
442022
CDC7-independent G1/S transition revealed by targeted protein degradation
JM Suski, N Ratnayeke, M Braun, T Zhang, V Strmiska, W Michowski, ...
Nature 605 (7909), 357-365, 2022
442022
BRG1 loss predisposes lung cancers to replicative stress and ATR dependency
M Gupta, CP Concepcion, CG Fahey, H Keshishian, A Bhutkar, ...
Cancer research 80 (18), 3841-3854, 2020
412020
Interplay between histone H3 lysine 56 deacetylation and chromatin modifiers in response to DNA damage
A Simoneau, N Delgoshaie, I Celic, J Dai, N Abshiru, S Costantino, ...
Genetics 200 (1), 185-205, 2015
392015
An extending ATR–CHK1 circuitry: the replication stress response and beyond
A Simoneau, L Zou
Current opinion in genetics & development 71, 92-98, 2021
322021
Chromosome-wide histone deacetylation by sirtuins prevents hyperactivation of DNA damage-induced signaling upon replicative stress
A Simoneau, E Ricard, S Weber, I Hammond-Martel, LH Wong, A Sellam, ...
Nucleic Acids Research 44 (6), 2706-2726, 2016
302016
Cdk1-dependent regulation of the Mre11 complex couples DNA repair pathways to cell cycle progression
A Simoneau, X Robellet, AM Ladouceur, D D’Amours
Cell Cycle 13 (7), 1078-1090, 2014
302014
CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer
T Tsujino, T Takai, K Hinohara, F Gui, T Tsutsumi, X Bai, C Miao, C Feng, ...
Nature Communications 14 (1), 252, 2023
272023
Translesion DNA synthesis mediates acquired resistance to olaparib plus temozolomide in small cell lung cancer
M Stanzione, J Zhong, E Wong, TJ LaSalle, JF Wise, A Simoneau, ...
Science Advances 8 (19), eabn1229, 2022
142022
Identification of Somatically Acquired BRCA1/2 Mutations by cfDNA Analysis in Patients with Metastatic Breast Cancer
N Vidula, T Dubash, MS Lawrence, A Simoneau, A Niemierko, E Blouch, ...
Clinical Cancer Research 26 (18), 4852-4862, 2020
142020
Ubiquitinated PCNA drives USP1 synthetic lethality in cancer
A Simoneau, JL Engel, M Bandi, K Lazarides, S Liu, SR Meier, AH Choi, ...
Molecular Cancer Therapeutics 22 (2), 215-226, 2023
122023
Valproate inhibits MAP kinase signalling and cell cycle progression in S. cerevisiae
K Desfossés-Baron, I Hammond-Martel, A Simoneau, A Sellam, S Roberts, ...
Scientific reports 6 (1), 36013, 2016
102016
An interplay between multiple sirtuins promotes completion of DNA replication in cells with short telomeres
A Simoneau, E Ricard, H Wurtele
PLoS Genetics 14 (4), e1007356, 2018
92018
ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms
W Leung, A Simoneau, S Saxena, J Jackson, PS Patel, M Limbu, ...
Cell reports 42 (7), 2023
72023
Calcium influx guards replication forks against exonuclease 1
A Simoneau, L Zou
Molecular cell 74 (6), 1103-1105, 2019
42019
Oncogenic KIT induces replication stress and confers cell cycle checkpoint vulnerability in melanoma
CN Njauw, Z Ji, DM Pham, A Simoneau, R Kumar, KT Flaherty, L Zou, ...
Journal of Investigative Dermatology 142 (5), 1413-1424. e6, 2022
32022
Persistent Acetylation of Histone H3 Lysine 56 Compromises the Activity of DNA Replication Origins
R Tremblay, Y Mehrjoo, O Ahmed, A Simoneau, ME McQuaid, EB Affar, ...
Molecular and Cellular Biology 43 (11), 566-595, 2023
12023
系统目前无法执行此操作,请稍后再试。
文章 1–20