Physiologically based pharmacokinetic modeling of metoprolol enantiomers and α-hydroxymetoprolol to describe CYP2D6 drug-gene interactions S Rüdesheim, JG Wojtyniak, D Selzer, N Hanke, F Mahfoud, M Schwab, ... Pharmaceutics 12 (12), 1200, 2020 | 18 | 2020 |
Physiologically‐based pharmacokinetic modeling of dextromethorphan to investigate interindividual variability within CYP2D6 activity score groups S Rüdesheim, D Selzer, U Fuhr, M Schwab, T Lehr CPT: Pharmacometrics & Systems Pharmacology 11 (4), 494-511, 2022 | 16 | 2022 |
Novel models for the prediction of drug–gene interactions D Türk, LM Fuhr, FZ Marok, S Rüdesheim, A Kühn, D Selzer, M Schwab, ... Expert Opinion on Drug Metabolism & Toxicology 17 (11), 1293-1310, 2021 | 14 | 2021 |
Physiologically based pharmacokinetic modeling to describe the CYP2D6 activity score-dependent metabolism of paroxetine, atomoxetine and risperidone S Rüdesheim, D Selzer, T Mürdter, S Igel, R Kerb, M Schwab, T Lehr Pharmaceutics 14 (8), 1734, 2022 | 5 | 2022 |
Physiologically‐based pharmacokinetic modeling of quinidine to establish a CYP3A4, P‐gp, and CYP2D6 drug–drug–gene interaction network D Feick, S Rüdesheim, FZ Marok, D Selzer, HLH Loer, D Teutonico, ... CPT: Pharmacometrics & Systems Pharmacology 12 (8), 1143-1156, 2023 | 3 | 2023 |
Physiologically based pharmacokinetic modeling of tacrolimus for food–drug and CYP3A drug–drug–gene interaction predictions HLH Loer, D Feick, S Rüdesheim, D Selzer, M Schwab, D Teutonico, ... CPT: Pharmacometrics & Systems Pharmacology 12 (5), 724-738, 2023 | 3 | 2023 |
Prediction of Drug–Drug–Gene Interaction Scenarios of (E)-Clomiphene and Its Metabolites Using Physiologically Based Pharmacokinetic Modeling C Kovar, L Kovar, S Rüdesheim, D Selzer, B Ganchev, P Kröner, S Igel, ... Pharmaceutics 14 (12), 2604, 2022 | 3 | 2022 |
Physiologically based pharmacokinetic modeling of imatinib and N‐desmethyl imatinib for drug–drug interaction predictions HLH Loer, C Kovar, S Rüdesheim, FZ Marok, LM Fuhr, D Selzer, ... CPT: Pharmacometrics & Systems Pharmacology 13 (6), 926-940, 2024 | | 2024 |
A physiologically‐based pharmacokinetic precision dosing approach to manage dasatinib drug–drug interactions C Kovar, HLH Loer, S Rüdesheim, LM Fuhr, FZ Marok, D Selzer, ... CPT: Pharmacometrics & Systems Pharmacology, 2024 | | 2024 |
Predicting the effect of drug-gene and drug-drug-gene interactions on the pharmacokinetics of CYP2D6 substrates: leveraging the activity score system in physiologically based … SM Rüdesheim Saarländische Universitäts-und Landesbibliothek, 2023 | | 2023 |