| N-Acylhydrazones as drugs S Thota, DA Rodrigues, PSM Pinheiro, LM Lima, CAM Fraga, EJ Barreiro Bioorganic & medicinal chemistry letters 28 (17), 2797-2806, 2018 | 174 | 2018 |
| From combinations to multitarget‐directed ligands: A continuum in Alzheimer's disease polypharmacology C Albertini, A Salerno, P de Sena Murteira Pinheiro, ML Bolognesi Medicinal Research Reviews 41 (5), 2606-2633, 2021 | 115 | 2021 |
| Histone deacetylases as targets for the treatment of neurodegenerative disorders: Challenges and future opportunities DA Rodrigues, PSM Pinheiro, FS Sagrillo, ML Bolognesi, CAM Fraga Medicinal Research Reviews 40 (6), 2177-2211, 2020 | 51 | 2020 |
| Design, Synthesis, and Pharmacological Evaluation of First‐in‐Class Multitarget N‐Acylhydrazone Derivatives as Selective HDAC6/8 and PI3Kα Inhibitors DA Rodrigues, FS Guerra, FS Sagrillo, P de Sena M. Pinheiro, MA Alves, ... ChemMedChem 15 (6), 539-551, 2020 | 37 | 2020 |
| The Use of Conformational Restriction in Medicinal Chemistry P de Sena M Pinheiro, DA Rodrigues, R do Couto Maia, S Thota, ... Current topics in medicinal chemistry 19 (19), 1712-1733, 2019 | 33 | 2019 |
| Multitarget inhibition of histone deacetylase (HDAC) and phosphatidylinositol‐3‐kinase (PI3K): Current and future prospects DA Rodrigues, PSM Pinheiro, CAM Fraga ChemMedChem 16 (3), 448-457, 2021 | 17 | 2021 |
| HÁ ALGO NOVO NO RECONHECIMENTO MOLECULAR APLICADO À QUÍMICA MEDICINAL? HH Fokoue, PSM Pinheiro, CAM Fraga, CMR Sant’Anna Química Nova 43, 78-89, 2020 | 17 | 2020 |
| The Magic Methyl and Its Tricks in Drug Discovery and Development PSM Pinheiro, LS Franco, CAM Fraga Pharmaceuticals 16 (8), 1157, 2023 | 16 | 2023 |
| Turning Donepezil into a Multi‐Target‐Directed Ligand through a Merging Strategy R Perone, C Albertini, E Uliassi, F Di Pietri, P de Sena Murteira Pinheiro, ... ChemMedChem 16 (1), 187-198, 2021 | 16 | 2021 |
| Structural basis for the agonist action at free fatty acid receptor 1 (FFA1R or GPR40) DA Rodrigues, PSM Pinheiro, TTSC Ferreira, S Thota, CAM Fraga Chemical biology & drug design 91 (3), 668-680, 2018 | 16 | 2018 |
| Theoretical and experimental characterization of 1, 4-N⋯ S σ-hole intramolecular interactions in bioactive N-acylhydrazone derivatives PSM Pinheiro, DA Rodrigues, MA Alves, LW Tinoco, GB Ferreira, ... New Journal of Chemistry 42 (1), 497-505, 2018 | 16 | 2018 |
| An Unusual Intramolecular Halogen Bond Guides Conformational Selection R Tesch, C Becker, MP Müller, ME Beck, L Quambusch, M Getlik, ... Angewandte Chemie International Edition 57 (31), 9970-9975, 2018 | 14 | 2018 |
| Molecular hybridization: a powerful tool for multitarget drug discovery P de Sena Murteira Pinheiro, LS Franco, TL Montagnoli, CAM Fraga Expert Opinion on Drug Discovery 19 (4), 451-470, 2024 | 8 | 2024 |
| Design, Synthesis, Experimental and Theoretical Characterization of a New Multitarget 2-Thienyl-N-Acylhydrazone Derivative I Bastos, P Pinheiro, F Costa, M Rocha, C Sant’Anna, D Braz, E Souza, ... Pharmaceuticals 11 (4), 119, 2018 | 8 | 2018 |
| IS THERE ANYTHING NEW ABOUT THE MOLECULAR RECOGNITION APPLIED TO MEDICINAL CHEMISTRY? HH Fokoue, PSM Pinheiro, CAM Fraga, CMR Sant’Anna Química Nova 43, 78-89, 2020 | 6 | 2020 |
| Modeling zinc‐oxygen coordination in histone deacetylase: A comparison of semiempirical methods performance PSM Pinheiro, DA Rodrigues, CMR Sant'Anna, CAM Fraga International Journal of Quantum Chemistry 118 (21), e25720, 2018 | 6 | 2018 |
| Design, Synthesis and Pharmacological Evaluation of Novel Conformationally Restricted N-arylpiperazine Derivatives Characterized as D2/D3 Receptor Ligands, Candidates for the … TT da Silva Cunha, RR Silva, DA Rodrigues, P de Sena Murteira Pinheiro, ... Biomolecules 12 (8), 1112, 2022 | 3 | 2022 |
| Structure–property relationship studies of 3-acyl-substituted furans: the serendipitous identification and characterization of a new non-classical hydrogen bond donor moiety DA Rodrigues, MP Pedro de Sena, FS Sagrillo, MCR Freitas, MA Alves, ... New Journal of Chemistry 44 (26), 10994-11005, 2020 | 3 | 2020 |
| Investigating the Molecular Basis for the Selective Inhibition of Aldehyde Dehydrogenase 2 by the Isoflavonoid Daidzin TT da Silva Cunha, FR de Souza, P de Sena Murteira Pinheiro, ... CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2020 | 2 | 2020 |
| Histone deacetylase inhibition mitigates cognitive deficits and astrocyte dysfunction induced by amyloid‐β (Aβ) oligomers LP Diniz, J Morgado, AP Bergamo Araujo, LM da Silva Antônio, ... British Journal of Pharmacology, 2024 | 1 | 2024 |
Carlos Alberto Manssour FragaProfessor de Farmacologia e Química Medicinal, Universidade Federal do Rio de Janeiro在 ccsdecania.ufrj.br 的电子邮件经过验证
