Modelling schizophrenia using human induced pluripotent stem cells KJ Brennand, A Simone, J Jou, C Gelboin-Burkhart, N Tran, S Sangar, ... Nature 473 (7346), 221-225, 2011 | 1625 | 2011 |
Gene expression elucidates functional impact of polygenic risk for schizophrenia M Fromer, P Roussos, SK Sieberts, JS Johnson, DH Kavanagh, ... Nature neuroscience 19 (11), 1442-1453, 2016 | 1082 | 2016 |
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen M Xu, EM Lee, Z Wen, Y Cheng, WK Huang, X Qian, J Tcw, ... Nature medicine 22 (10), 1101-1107, 2016 | 697 | 2016 |
Mosaic copy number variation in human neurons MJ McConnell, MR Lindberg, KJ Brennand, JC Piper, T Voet, ... Science 342 (6158), 632-637, 2013 | 588 | 2013 |
Reprogramming of pancreatic β cells into induced pluripotent stem cells M Stadtfeld, K Brennand, K Hochedlinger Current Biology 18 (12), 890-894, 2008 | 581 | 2008 |
Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder J Mertens, QW Wang, Y Kim, DX Yu, S Pham, B Yang, Y Zheng, ... Nature 527 (7576), 95-99, 2015 | 516 | 2015 |
Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia K Brennand, JN Savas, Y Kim, N Tran, A Simone, K Hashimoto-Torii, ... Molecular psychiatry 20 (3), 361-368, 2015 | 426 | 2015 |
Altered proliferation and networks in neural cells derived from idiopathic autistic individuals MC Marchetto, H Belinson, Y Tian, BC Freitas, C Fu, KC Vadodaria, ... Molecular psychiatry 22 (6), 820-835, 2017 | 412 | 2017 |
An efficient platform for astrocyte differentiation from human induced pluripotent stem cells TCW Julia, M Wang, AA Pimenova, KR Bowles, BJ Hartley, E Lacin, ... Stem cell reports 9 (2), 600-614, 2017 | 380 | 2017 |
Modeling hippocampal neurogenesis using human pluripotent stem cells DX Yu, FP Di Giorgio, J Yao, MC Marchetto, K Brennand, R Wright, A Mei, ... Stem cell reports 2 (3), 295-310, 2014 | 314 | 2014 |
A role for noncoding variation in schizophrenia P Roussos, AC Mitchell, G Voloudakis, JF Fullard, VM Pothula, J Tsang, ... Cell reports 9 (4), 1417-1429, 2014 | 270 | 2014 |
All β cells contribute equally to islet growth and maintenance K Brennand, D Huangfu, D Melton PLoS biology 5 (7), e163, 2007 | 269 | 2007 |
Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer’s disease M Wang, P Roussos, A McKenzie, X Zhou, Y Kajiwara, KJ Brennand, ... Genome medicine 8, 1-21, 2016 | 265 | 2016 |
High-content screening in hPSC-neural progenitors identifies drug candidates that inhibit Zika virus infection in fetal-like organoids and adult brain T Zhou, L Tan, GY Cederquist, Y Fan, BJ Hartley, S Mukherjee, ... Cell stem cell 21 (2), 274-283. e5, 2017 | 242 | 2017 |
A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles NYA Sey, B Hu, W Mah, H Fauni, JC McAfee, P Rajarajan, KJ Brennand, ... Nature Neuroscience 23 (4), 583-593, 2020 | 219 | 2020 |
Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises MC Marchetto, KJ Brennand, LF Boyer, FH Gage Human molecular genetics 20 (R2), R109-R115, 2011 | 217 | 2011 |
Synergistic effects of common schizophrenia risk variants N Schrode, SM Ho, K Yamamuro, A Dobbyn, L Huckins, MR Matos, ... Nature genetics 51 (10), 1475-1485, 2019 | 210 | 2019 |
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk P Rajarajan, T Borrman, W Liao, N Schrode, E Flaherty, C Casiño, ... Science 362 (6420), eaat4311, 2018 | 202 | 2018 |
Investigating synapse formation and function using human pluripotent stem cell-derived neurons JE Kim, ML O'Sullivan, CA Sanchez, M Hwang, MA Israel, K Brennand, ... Proceedings of the National Academy of Sciences 108 (7), 3005-3010, 2011 | 180 | 2011 |
Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets RA Neff, M Wang, S Vatansever, L Guo, C Ming, Q Wang, E Wang, ... Science advances 7 (2), eabb5398, 2021 | 175 | 2021 |