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Kristen Brennand
Kristen Brennand
Professor, Yale University
在 yale.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Modelling schizophrenia using human induced pluripotent stem cells
KJ Brennand, A Simone, J Jou, C Gelboin-Burkhart, N Tran, S Sangar, ...
Nature 473 (7346), 221-225, 2011
16252011
Gene expression elucidates functional impact of polygenic risk for schizophrenia
M Fromer, P Roussos, SK Sieberts, JS Johnson, DH Kavanagh, ...
Nature neuroscience 19 (11), 1442-1453, 2016
10822016
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
M Xu, EM Lee, Z Wen, Y Cheng, WK Huang, X Qian, J Tcw, ...
Nature medicine 22 (10), 1101-1107, 2016
6972016
Mosaic copy number variation in human neurons
MJ McConnell, MR Lindberg, KJ Brennand, JC Piper, T Voet, ...
Science 342 (6158), 632-637, 2013
5882013
Reprogramming of pancreatic β cells into induced pluripotent stem cells
M Stadtfeld, K Brennand, K Hochedlinger
Current Biology 18 (12), 890-894, 2008
5812008
Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder
J Mertens, QW Wang, Y Kim, DX Yu, S Pham, B Yang, Y Zheng, ...
Nature 527 (7576), 95-99, 2015
5162015
Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia
K Brennand, JN Savas, Y Kim, N Tran, A Simone, K Hashimoto-Torii, ...
Molecular psychiatry 20 (3), 361-368, 2015
4262015
Altered proliferation and networks in neural cells derived from idiopathic autistic individuals
MC Marchetto, H Belinson, Y Tian, BC Freitas, C Fu, KC Vadodaria, ...
Molecular psychiatry 22 (6), 820-835, 2017
4122017
An efficient platform for astrocyte differentiation from human induced pluripotent stem cells
TCW Julia, M Wang, AA Pimenova, KR Bowles, BJ Hartley, E Lacin, ...
Stem cell reports 9 (2), 600-614, 2017
3802017
Modeling hippocampal neurogenesis using human pluripotent stem cells
DX Yu, FP Di Giorgio, J Yao, MC Marchetto, K Brennand, R Wright, A Mei, ...
Stem cell reports 2 (3), 295-310, 2014
3142014
A role for noncoding variation in schizophrenia
P Roussos, AC Mitchell, G Voloudakis, JF Fullard, VM Pothula, J Tsang, ...
Cell reports 9 (4), 1417-1429, 2014
2702014
All β cells contribute equally to islet growth and maintenance
K Brennand, D Huangfu, D Melton
PLoS biology 5 (7), e163, 2007
2692007
Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer’s disease
M Wang, P Roussos, A McKenzie, X Zhou, Y Kajiwara, KJ Brennand, ...
Genome medicine 8, 1-21, 2016
2652016
High-content screening in hPSC-neural progenitors identifies drug candidates that inhibit Zika virus infection in fetal-like organoids and adult brain
T Zhou, L Tan, GY Cederquist, Y Fan, BJ Hartley, S Mukherjee, ...
Cell stem cell 21 (2), 274-283. e5, 2017
2422017
A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles
NYA Sey, B Hu, W Mah, H Fauni, JC McAfee, P Rajarajan, KJ Brennand, ...
Nature Neuroscience 23 (4), 583-593, 2020
2192020
Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises
MC Marchetto, KJ Brennand, LF Boyer, FH Gage
Human molecular genetics 20 (R2), R109-R115, 2011
2172011
Synergistic effects of common schizophrenia risk variants
N Schrode, SM Ho, K Yamamuro, A Dobbyn, L Huckins, MR Matos, ...
Nature genetics 51 (10), 1475-1485, 2019
2102019
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk
P Rajarajan, T Borrman, W Liao, N Schrode, E Flaherty, C Casiño, ...
Science 362 (6420), eaat4311, 2018
2022018
Investigating synapse formation and function using human pluripotent stem cell-derived neurons
JE Kim, ML O'Sullivan, CA Sanchez, M Hwang, MA Israel, K Brennand, ...
Proceedings of the National Academy of Sciences 108 (7), 3005-3010, 2011
1802011
Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets
RA Neff, M Wang, S Vatansever, L Guo, C Ming, Q Wang, E Wang, ...
Science advances 7 (2), eabb5398, 2021
1752021
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