Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts TK Karikari, TA Pascoal, NJ Ashton, S Janelidze, AL Benedet, ... The Lancet Neurology 19 (5), 422-433, 2020 | 950 | 2020 |
Microglial activation and tau propagate jointly across Braak stages TA Pascoal, AL Benedet, NJ Ashton, MS Kang, J Therriault, M Chamoun, ... Nature medicine 27 (9), 1592-1599, 2021 | 354 | 2021 |
Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain KP Ng, TA Pascoal, S Mathotaarachchi, J Therriault, MS Kang, M Shin, ... Alzheimer's research & therapy 9, 1-9, 2017 | 343 | 2017 |
Differences between plasma and cerebrospinal fluid glial fibrillary acidic protein levels across the Alzheimer disease continuum AL Benedet, M Milà-Alomà, A Vrillon, NJ Ashton, TA Pascoal, F Lussier, ... JAMA neurology 78 (12), 1471-1483, 2021 | 296 | 2021 |
Association of apolipoprotein E ε4 with medial temporal tau independent of amyloid-β J Therriault, AL Benedet, TA Pascoal, S Mathotaarachchi, M Chamoun, ... JAMA neurology 77 (4), 470-479, 2020 | 203 | 2020 |
18F-MK-6240 PET for early and late detection of neurofibrillary tangles TA Pascoal, J Therriault, AL Benedet, M Savard, FZ Lussier, M Chamoun, ... Brain 143 (9), 2818-2830, 2020 | 186 | 2020 |
In vivo quantification of neurofibrillary tangles with [18F]MK-6240 TA Pascoal, M Shin, MS Kang, M Chamoun, D Chartrand, ... Alzheimer's research & therapy 10, 1-14, 2018 | 154 | 2018 |
Biomarker modeling of Alzheimer’s disease using PET-based Braak staging J Therriault, TA Pascoal, FZ Lussier, C Tissot, M Chamoun, G Bezgin, ... Nature aging 2 (6), 526-535, 2022 | 141 | 2022 |
Mild behavioral impairment is associated with β‐amyloid but not tau or neurodegeneration in cognitively intact elderly individuals FZ Lussier, TA Pascoal, M Chamoun, J Therriault, C Tissot, M Savard, ... Alzheimer's & dementia 16 (1), 192-199, 2020 | 139 | 2020 |
Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease B Bellaver, G Povala, PCL Ferreira, JP Ferrari-Souza, DT Leffa, ... Nature medicine 29 (7), 1775-1781, 2023 | 122 | 2023 |
Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease NJ Ashton, AL Benedet, TA Pascoal, TK Karikari, J Lantero-Rodriguez, ... EBioMedicine 76, 2022 | 110 | 2022 |
Association of phosphorylated tau biomarkers with amyloid positron emission tomography vs tau positron emission tomography J Therriault, M Vermeiren, S Servaes, C Tissot, NJ Ashton, AL Benedet, ... JAMA neurology 80 (2), 188-199, 2023 | 98 | 2023 |
Diagnostic accuracy of a plasma phosphorylated tau 217 immunoassay for Alzheimer disease pathology NJ Ashton, WS Brum, G Di Molfetta, AL Benedet, B Arslan, E Jonaitis, ... JAMA neurology 81 (3), 255-263, 2024 | 93 | 2024 |
Cerebrospinal fluid synaptosomal-associated protein 25 is a key player in synaptic degeneration in mild cognitive impairment and Alzheimer’s disease H Zhang, J Therriault, MS Kang, KP Ng, TA Pascoal, P Rosa-Neto, ... Alzheimer's research & therapy 10, 1-11, 2018 | 85 | 2018 |
Determining amyloid-β positivity using 18F-AZD4694 PET imaging J Therriault, AL Benedet, TA Pascoal, M Savard, NJ Ashton, M Chamoun, ... Journal of Nuclear Medicine 62 (2), 247-252, 2021 | 84 | 2021 |
Stage-specific links between plasma neurofilament light and imaging biomarkers of Alzheimer’s disease AL Benedet, A Leuzy, TA Pascoal, NJ Ashton, S Mathotaarachchi, ... Brain 143 (12), 3793-3804, 2020 | 81 | 2020 |
APOEε4 potentiates the relationship between amyloid-β and tau pathologies J Therriault, AL Benedet, TA Pascoal, S Mathotaarachchi, M Savard, ... Molecular psychiatry 26 (10), 5977-5988, 2021 | 77 | 2021 |
Astrocyte biomarker signatures of amyloid-β and tau pathologies in Alzheimer’s disease JP Ferrari-Souza, PCL Ferreira, B Bellaver, C Tissot, YT Wang, DT Leffa, ... Molecular psychiatry 27 (11), 4781-4789, 2022 | 73 | 2022 |
Aβ-induced vulnerability propagates via the brain’s default mode network TA Pascoal, S Mathotaarachchi, MS Kang, S Mohaddes, M Shin, AY Park, ... Nature communications 10 (1), 2353, 2019 | 71 | 2019 |
Plasma neurofilament light associates with Alzheimer's disease metabolic decline in amyloid‐positive individuals AL Benedet, NJ Ashton, TA Pascoal, A Leuzy, S Mathotaarachchi, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 11 (1 …, 2019 | 70 | 2019 |