Catalytic “click” rotaxanes: a substoichiometric metal-template pathway to mechanically interlocked architectures V Aucagne, KD Hänni, DA Leigh, PJ Lusby, DB Walker Journal of the American Chemical Society 128 (7), 2186-2187, 2006 | 463 | 2006 |
Catalytic “active-metal” template synthesis of [2] rotaxanes,[3] rotaxanes, and molecular shuttles, and some observations on the mechanism of the cu (I)-catalyzed Azide− Alkyne … V Aucagne, J Berná, JD Crowley, SM Goldup, KD Hänni, DA Leigh, ... Journal of the American Chemical Society 129 (39), 11950-11963, 2007 | 306 | 2007 |
Chemoselective formation of successive triazole linkages in One Pot:“Click− Click” chemistry V Aucagne, DA Leigh Organic letters 8 (20), 4505-4507, 2006 | 281 | 2006 |
Rotaxane-based propeptides: Protection and enzymatic release of a bioactive pentapeptide A Fernandes, A Viterisi, F Coutrot, S Potok, DA Leigh, V Aucagne, S Papot Angew. Chem. Int. Ed 48 (35), 6443, 2009 | 139 | 2009 |
A mechanically interlocked molecular system programmed for the delivery of an anticancer drug R Barat, T Legigan, I Tranoy-Opalinski, B Renoux, E Péraudeau, ... Chemical Science 6 (4), 2608-2613, 2015 | 136 | 2015 |
Synthesis of a biologically active triazole‐containing analogue of cystatin A through successive peptidomimetic alkyne–azide ligations IE Valverde, F Lecaille, G Lalmanach, V Aucagne, AF Delmas Angewandte Chemie International Edition 51 (3), 718-722, 2012 | 100 | 2012 |
Click à la carte: robust semi-orthogonal alkyne protecting groups for multiple successive azide/alkyne cycloadditions IE Valverde, AF Delmas, V Aucagne Tetrahedron 65 (36), 7597-7602, 2009 | 90 | 2009 |
A helping hand to overcome solubility challenges in chemical protein synthesis MT Jacobsen, ME Petersen, X Ye, M Galibert, GH Lorimer, V Aucagne, ... Journal of the American Chemical Society 138 (36), 11775-11782, 2016 | 82 | 2016 |
A synthetic kisspeptin analog that triggers ovulation and advances puberty C Decourt, V Robert, K Anger, M Galibert, JB Madinier, X Liu, H Dardente, ... Scientific reports 6 (1), 26908, 2016 | 81 | 2016 |
Synthesis and antiviral activity of novel acyclic nucleosides in the 5-alkynyl- and 6-alkylfuro[2,3-d]pyrimidine series F Amblard, V Aucagne, P Guenot, RF Schinazi, LA Agrofoglio Bioorganic & medicinal chemistry 13 (4), 1239-1248, 2005 | 81 | 2005 |
Towards the simplification of protein synthesis: iterative solid‐supported ligations with concomitant purifications V Aucagne, IE Valverde, P Marceau, M Galibert, N Dendane, AF Delmas Angewandte Chemie 124 (45), 11482-11486, 2012 | 75 | 2012 |
A straightforward method for automated Fmoc-based synthesis of bio-inspired peptide crypto-thioesters VP Terrier, H Adihou, M Arnould, AF Delmas, V Aucagne Chemical Science 7 (1), 339-345, 2016 | 69 | 2016 |
Highly efficient solid phase synthesis of large polypeptides by iterative ligations of bis (2-sulfanylethyl) amido (SEA) peptide segments L Raibaut, H Adihou, R Desmet, AF Delmas, V Aucagne, O Melnyk Chemical Science 4 (10), 4061-4066, 2013 | 67 | 2013 |
Primary structure and antibacterial activity of chicken bone marrow-derived β-defensins C Derache, V Labas, V Aucagne, H Meudal, C Landon, AF Delmas, ... Antimicrobial agents and chemotherapy 53 (11), 4647-4655, 2009 | 61 | 2009 |
Sulfur-containing amide-based [2] rotaxanes and molecular shuttles A Altieri, V Aucagne, R Carrillo, GJ Clarkson, DM D'Souza, JA Dunnett, ... Chemical Science 2 (10), 1922-1928, 2011 | 54 | 2011 |
Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells A Gambade, S Zreika, M Guéguinou, I Chourpa, G Fromont, AM Bouchet, ... Oncotarget 7 (17), 23785, 2016 | 53 | 2016 |
Second generation specific-enzyme-activated rotaxane propeptides A Fernandes, A Viterisi, V Aucagne, DA Leigh, S Papot Chemical Communications 48 (15), 2083-2085, 2012 | 52 | 2012 |
Wittig approach to carbohydrate-derived vinyl sulfides, new substrates for regiocontrolled ring-closure reactions V Aucagne, A Tatibouët, P Rollin Tetrahedron 60 (8), 1817-1826, 2004 | 46 | 2004 |
Rational design of triazololipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotropins M Beltramo, V Robert, M Galibert, JB Madinier, P Marceau, H Dardente, ... Journal of medicinal chemistry 58 (8), 3459-3470, 2015 | 44 | 2015 |
Rotaxanes of cyclic peptides V Aucagne, DA Leigh, JS Lock, AR Thomson Journal of the American Chemical Society 128 (6), 1784-1785, 2006 | 44 | 2006 |