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| Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 5576 | 2018 |
| BAX activation is initiated at a novel interaction site E Gavathiotis, M Suzuki, ML Davis, K Pitter, GH Bird, SG Katz, HC Tu, ... Nature 455 (7216), 1076-1081, 2008 | 848 | 2008 |
| The advantages of targeted protein degradation over inhibition: an RTK case study GM Burslem, BE Smith, AC Lai, S Jaime-Figueroa, DC McQuaid, ... Cell chemical biology 25 (1), 67-77. e3, 2018 | 539 | 2018 |
| Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic GH Bird, N Madani, AF Perry, AM Princiotto, JG Supko, X He, ... Proceedings of the National Academy of Sciences 107 (32), 14093-14098, 2010 | 393 | 2010 |
| New perspectives for targeting RAF kinase in human cancer Z Karoulia, E Gavathiotis, PI Poulikakos Nature Reviews Cancer 17 (11), 676-691, 2017 | 363 | 2017 |
| BH3-triggered structural reorganization drives the activation of proapoptotic BAX E Gavathiotis, DE Reyna, ML Davis, GH Bird, LD Walensky Molecular cell 40 (3), 481-492, 2010 | 339 | 2010 |
| Bax regulates primary necrosis through mitochondrial dynamics RS Whelan, K Konstantinidis, AC Wei, Y Chen, DE Reyna, S Jha, Y Yang, ... Proceedings of the National Academy of Sciences 109 (17), 6566-6571, 2012 | 319 | 2012 |
| An interconnected hierarchical model of cell death regulation by the BCL-2 family HC Chen, M Kanai, A Inoue-Yamauchi, HC Tu, Y Huang, D Ren, H Kim, ... Nature cell biology 17 (10), 1270-1281, 2015 | 297 | 2015 |
| The structure of FADD and its mode of interaction with procaspase-8 PE Carrington, C Sandu, Y Wei, JM Hill, G Morisawa, T Huang, ... Molecular cell 22 (5), 599-610, 2006 | 251 | 2006 |
| MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A AG Rocha, A Franco, AM Krezel, JM Rumsey, JM Alberti, WC Knight, ... Science 360 (6386), 336-341, 2018 | 237 | 2018 |
| Correcting mitochondrial fusion by manipulating mitofusin conformations A Franco, RN Kitsis, JA Fleischer, E Gavathiotis, OS Kornfeld, G Gong, ... Nature 540 (7631), 74-79, 2016 | 230 | 2016 |
| Drug recognition and stabilisation of the parallel-stranded DNA quadruplex d (TTAGGGT) 4 containing the human telomeric repeat E Gavathiotis, RA Heald, MFG Stevens, MS Searle Journal of molecular biology 334 (1), 25-36, 2003 | 230 | 2003 |
| Targeting mitochondrial structure sensitizes acute myeloid leukemia to venetoclax treatment X Chen, C Glytsou, H Zhou, S Narang, DE Reyna, A Lopez, ... Cancer discovery 9 (7), 890-909, 2019 | 222 | 2019 |
| BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore LD Walensky, E Gavathiotis Trends in biochemical sciences 36 (12), 642-652, 2011 | 219 | 2011 |
| Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives J Anguiano, TP Garner, M Mahalingam, BC Das, E Gavathiotis, ... Nature chemical biology 9 (6), 374-382, 2013 | 203 | 2013 |
| A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers JL LaBelle, SG Katz, GH Bird, E Gavathiotis, ML Stewart, C Lawrence, ... The Journal of clinical investigation 122 (6), 2018-2031, 2012 | 201 | 2012 |
| Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome M Bourdenx, A Martín-Segura, A Scrivo, JA Rodriguez-Navarro, ... Cell 184 (10), 2696-2714. e25, 2021 | 195 | 2021 |
| Direct and selective small-molecule activation of proapoptotic BAX E Gavathiotis, DE Reyna, JA Bellairs, ES Leshchiner, LD Walensky Nature chemical biology 8 (7), 639-645, 2012 | 193 | 2012 |
| Cooperativity in drug− DNA recognition: a molecular dynamics study SA Harris, E Gavathiotis, MS Searle, M Orozco, CA Laughton Journal of the American Chemical Society 123 (50), 12658-12663, 2001 | 189 | 2001 |
