The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis Q Chang, E Bournazou, P Sansone, M Berishaj, SP Gao, L Daly, J Wels, ... Neoplasia 15 (7), 848-IN45, 2013 | 498 | 2013 |
Single‐cell quantification of IL‐2 response by effector and regulatory T cells reveals critical plasticity in immune response O Feinerman, G Jentsch, KE Tkach, JW Coward, MM Hathorn, ... Molecular systems biology 6 (1), 437, 2010 | 243 | 2010 |
Dectin-1 diversifies Aspergillus fumigatus–specific T cell responses by inhibiting T helper type 1 CD4 T cell differentiation A Rivera, TM Hohl, N Collins, I Leiner, A Gallegos, S Saijo, JW Coward, ... The Journal of experimental medicine 208 (2), 369, 2011 | 198 | 2011 |
Safingol (L-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway J Coward, G Ambrosini, E Musi, JP Truman, A Haimovitz-Friedman, ... Autophagy 5 (2), 184-193, 2009 | 131 | 2009 |
Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780 JS Nair, AL Ho, AN Tse, J Coward, H Cheema, G Ambrosini, N Keen, ... Molecular biology of the cell 20 (8), 2218-2228, 2009 | 117 | 2009 |
Cell-to-cell variability analysis dissects the plasticity of signaling of common γ chain cytokines in T cells JW Cotari, G Voisinne, OE Dar, V Karabacak, G Altan-Bonnet Science signaling 6 (266), ra17-ra17, 2013 | 72 | 2013 |
T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks KE Tkach, D Barik, G Voisinne, N Malandro, MM Hathorn, JW Cotari, ... Elife 3, e01944, 2014 | 71 | 2014 |
Human Langerhans cells use an IL-15R-α/IL-15/pSTAT5-dependent mechanism to break T-cell tolerance against the self-differentiation tumor antigen WT1 E Romano, JW Cotari, R Barreira da Silva, BC Betts, DJ Chung, ... Blood, The Journal of the American Society of Hematology 119 (22), 5182-5190, 2012 | 58 | 2012 |
EGFR and PDGFRA co-expression and heterodimerization in glioblastoma tumor sphere lines D Chakravarty, AM Pedraza, J Cotari, AH Liu, D Punko, A Kokroo, ... Scientific reports 7 (1), 9043, 2017 | 39 | 2017 |
Perspectives for computer modeling in the study of T cell activation J Coward, RN Germain, G Altan-Bonnet Cold Spring Harbor perspectives in biology 2 (6), a005538, 2010 | 21 | 2010 |
Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells ML Palomba, K Piersanti, CGK Ziegler, H Decker, JW Cotari, K Bantilan, ... PLoS One 9 (1), e79987, 2014 | 20 | 2014 |
Diversity training for signal transduction: leveraging cell-to-cell variability to dissect cellular signaling, differentiation and death JW Cotari, G Voisinne, G Altan-Bonnet Current opinion in biotechnology 24 (4), 760-766, 2013 | 14 | 2013 |
Dissecting common γ chain cytokine family signaling in T cells using cell-to-cell variability analysis JW Cotari, G Voisinne, OE Dar, V Karabacak, G Altan-Bonnet Science signaling 6 (266), ra17, 2013 | 7 | 2013 |
Tuning of cytokine signaling through imbalanced abundances of receptors and kinases L Sta, G Voisinne, J Cotari, MF Adamer, C Molina-París, G Altan-Bonnet bioRxiv, 2022.10. 07.511173, 2022 | 2 | 2022 |
Safingol, an inhibitor of sphingosine kinase, stimulates autophagy in a ceramide-independent and phosphatidylinositol (PI)-3 kinase-mediated manner J Coward, JP Truman, G Ambrosini, A Haimovitz-Friedman, GK Schwartz Cancer Research 65 (9_Supplement), 784-785, 2005 | 1 | 2005 |
Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of Chronic Lymphocytic Leukemia B cells. ML Palomba, K Piersanti, CGK Ziegler, J Cotari, R Balderas, SN Malek, ... Cancer Research 73 (8_Supplement), 2886-2886, 2013 | | 2013 |
Role of intratumoral cell heterogeneity on therapeutic efficacy in glioblastoma. D Chakravarty, A Pedraza, AH Liu, J Cotari, G Altan-Bonnet, CW Brennan Cancer Research 73 (8_Supplement), 4627-4627, 2013 | | 2013 |
Cell-to-Cell Variability Analysis Dissects the Plasticity of Signaling of G Altan-Bonnet, JW Cotari, G Voisinne, OE Dar, V Karabacak | | |
Time Integration of Signal Feedbacks Generates Intensive Scaling of Cytokine Regulation K Tkach, D Barik, M Hathorn, J Cotari, R Vogel, O Krichevsky, ... | | |