Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release EO Samstad, N Niyonzima, S Nymo, MH Aune, L Ryan, SS Bakke, ... The Journal of Immunology 192 (6), 2837-2845, 2014 | 290 | 2014 |
SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation B Yan, T Freiwald, D Chauss, L Wang, E West, C Mirabelli, CJ Zhang, ... Science immunology 6 (58), eabg0833, 2021 | 161 | 2021 |
Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism G Arbore, EE West, J Rahman, G Le Friec, N Niyonzima, M Pirooznia, ... Nature communications 9 (1), 4186, 2018 | 88 | 2018 |
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation N Niyonzima, J Rahman, N Kunz, EE West, T Freiwald, JV Desai, ... Science immunology 6 (66), eabf2489, 2021 | 72 | 2021 |
Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis N Niyonzima, SS Bakke, I Gregersen, S Holm, Ø Sandanger, HL Orrem, ... EBioMedicine 60, 2020 | 54 | 2020 |
Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF S Nymo, N Niyonzima, T Espevik, TE Mollnes Immunobiology 219 (10), 786-792, 2014 | 53 | 2014 |
Cholesterol crystals activate the lectin complement pathway via ficolin-2 and mannose-binding lectin: implications for the progression of atherosclerosis K Pilely, A Rosbjerg, N Genster, P Gal, G Pál, B Halvorsen, S Holm, ... The Journal of Immunology 196 (12), 5064-5074, 2016 | 45 | 2016 |
Reconstituted high-density lipoprotein attenuates cholesterol crystal–induced inflammatory responses by reducing complement activation N Niyonzima, EO Samstad, MH Aune, L Ryan, SS Bakke, AM Rokstad, ... The Journal of Immunology 195 (1), 257-264, 2015 | 43 | 2015 |
Cyclodextrin reduces cholesterol crystal–induced inflammation by modulating complement activation SS Bakke, MH Aune, N Niyonzima, K Pilely, L Ryan, M Skjelland, ... The Journal of Immunology 199 (8), 2910-2920, 2017 | 39 | 2017 |
Complement activation by cholesterol crystals triggers a subsequent cytokine response N Niyonzima, B Halvorsen, B Sporsheim, P Garred, P Aukrust, TE Mollnes, ... Molecular immunology 84, 43-50, 2017 | 37 | 2017 |
Complement's favourite organelle—Mitochondria? J Rahman, P Singh, NS Merle, N Niyonzima, C Kemper British Journal of Pharmacology 178 (14), 2771-2785, 2021 | 25 | 2021 |
SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation. Sci Immunol 6: eabg0833 B Yan, T Freiwald, D Chauss, L Wang, E West, C Mirabelli, CJ Zhang, ... | 5 | 2021 |
Auto-regulation of Th1 responses through carboxypeptidase M-generated C5a-desArg EE West, S Freeley, G Le Friec, M Kolev, N Niyonzima, T Espevik, ... Molecular Immunology 89, 135, 2017 | 3 | 2017 |
Complement receptor CD46 costimulates optimal human CD8 T cell effector function via fatty acid metabolism. Nat Commun 9: 4186 G Arbore, EE West, J Rahman, G Le Friec, N Niyonzima, M Pirooznia, ... | 2 | 2018 |
Activation of Systemic-and Intracellular Complement by Cholesterol Crystals N Niyonzima, C Kemper, B Halvorsen, TE Mollnes, T Espevik Cholesterol Crystals in Atherosclerosis and Other Related Diseases, 233-255, 2023 | 1 | 2023 |
Auto-regulation of Th1 responses requires intracellular carboxypeptidase M-mediated complement regulation EE West, S Freeley, M Kolev, N Niyonzima, T Espevik, TE Mollnes, ... Molecular Immunology 102, 228-228, 2018 | 1 | 2018 |
Systemic-and local complement activation controls the NLRP3 inflammasome pathway in patients with atherosclerosis T Espevik, N Niyonzima, S Bakke, B Halvorsen, I Gregersen, M Skjelland, ... Molecular Immunology 89, 125-126, 2017 | 1 | 2017 |
The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes N Niyonzima, S Freeley, G Arbore, G Le Friec, KT Lappegård, TE Mollnes, ... The Journal of Immunology 198 (1_Supplement), 75.8-75.8, 2017 | 1 | 2017 |
Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner S Nymo, EO Samstad, N Niyonzima, MH Aune, G Bergseth, L Ryan, ... Molecular Immunology 3 (56), 246, 2013 | 1 | 2013 |
T cell-intrinsic C5L2 activation protects against uncontrolled inflammatory Th responses and autoimmunity NS Merle, S Freeley, J Bibby, P Singh, J Rahman, M Kolev, N Niyonzima, ... The Journal of Immunology 210 (1_Supplement), 64.15-64.15, 2023 | | 2023 |