Ferroptotic pores induce Ca2+ fluxes and ESCRT-III activation to modulate cell death kinetics L Pedrera, RA Espiritu, U Ros, J Weber, A Schmitt, J Stroh, S Hailfinger, ... Cell Death & Differentiation 28 (5), 1644-1657, 2021 | 194 | 2021 |
Pore formation in regulated cell death H Flores‐Romero, U Ros, AJ Garcia‐Saez The EMBO journal 39 (23), e105753, 2020 | 140 | 2020 |
Necroptosis execution is mediated by plasma membrane nanopores independent of calcium U Ros, A Peña-Blanco, K Hänggi, U Kunzendorf, S Krautwald, ... Cell reports 19 (1), 175-187, 2017 | 121 | 2017 |
Assembling the puzzle: Oligomerization of α-pore forming proteins in membranes K Cosentino, U Ros, AJ Garcia-Saez Biochimica Et Biophysica Acta (BBA)-Biomembranes 1858 (3), 457-466, 2016 | 80 | 2016 |
More than a pore: the interplay of pore-forming proteins and lipid membranes U Ros, AJ García-Sáez The Journal of membrane biology 248, 545-561, 2015 | 78 | 2015 |
Model peptides mimic the structure and function of the N‐terminus of the pore‐forming toxin sticholysin II F Casallanovo, FJF de Oliveira, FC de Souza, U Ros, Y Martínez, ... Peptide Science: Original Research on Biomolecules 84 (2), 169-180, 2006 | 74 | 2006 |
Toxicity of an α-pore-forming toxin depends on the assembly mechanism on the target membrane as revealed by single molecule imaging Y Subburaj, U Ros, E Hermann, R Tong, AJ García-Sáez Journal of Biological Chemistry 290 (8), 4856-4865, 2015 | 63 | 2015 |
Damage of eukaryotic cells by the pore-forming toxin sticholysin II: Consequences of the potassium efflux S Cabezas, S Ho, U Ros, ME Lanio, C Alvarez, FG Van Der Goot Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (5), 982-992, 2017 | 55 | 2017 |
Sticholysin I–membrane interaction: An interplay between the presence of sphingomyelin and membrane fluidity L Pedrera, ML Fanani, U Ros, ME Lanio, B Maggio, C Álvarez Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (7), 1752-1759, 2014 | 55 | 2014 |
The presence of sterols favors sticholysin I-membrane association and pore formation regardless of their ability to form laterally segregated domains L Pedrera, AB Gomide, RE Sánchez, U Ros, N Wilke, F Pazos, ME Lanio, ... Langmuir 31 (36), 9911-9923, 2015 | 42 | 2015 |
The sticholysin family of pore-forming toxins induces the mixing of lipids in membrane domains U Ros, MA Edwards, RF Epand, ME Lanio, S Schreier, CM Yip, C Alvarez, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (11), 2757-2762, 2013 | 40 | 2013 |
Single event visualization of unconventional secretion of FGF2 E Dimou, K Cosentino, E Platonova, U Ros, M Sadeghi, P Kashyap, ... Journal of Cell Biology 218 (2), 683-699, 2019 | 39 | 2019 |
Differences in activity of actinoporins are related with the hydrophobicity of their N-terminus U Ros, W Rodríguez-Vera, L Pedrera, PA Valiente, S Cabezas, ME Lanio, ... Biochimie 116, 70-78, 2015 | 35 | 2015 |
Correlations between differences in amino-terminal sequences and different hemolytic activity of sticholysins EM Cilli, FT Pigossi, E Crusca Jr, U Ros, D Martinez, ME Lanio, C Alvarez, ... Toxicon 50 (8), 1201-1204, 2007 | 35 | 2007 |
The membranotropic activity of N-terminal peptides from the pore-forming proteins sticholysin I and II is modulated by hydrophobic and electrostatic interactions as well as … U Ros, L Pedrera, D Díaz, JC De Karam, TP Sudbrack, PA Valiente, ... Journal of biosciences 36, 781-791, 2011 | 29 | 2011 |
Partners in crime: the interplay of proteins and membranes in regulated necrosis U Ros, L Pedrera, AJ Garcia-Saez International Journal of Molecular Sciences 21 (7), 2412, 2020 | 27 | 2020 |
Disrupting a key hydrophobic pair in the oligomerization interface of the actinoporins impairs their pore‐forming activity H Mesa‐Galloso, KH Delgado‐Magnero, S Cabezas, A López‐Castilla, ... Protein Science 26 (3), 550-565, 2017 | 27 | 2017 |
Biophysical and biochemical strategies to understand membrane binding and pore formation by sticholysins, pore-forming proteins from a sea anemone C Alvarez, U Ros, A Valle, L Pedrera, C Soto, YP Hervis, S Cabezas, ... Biophysical reviews 9, 529-544, 2017 | 25 | 2017 |
A lipid perspective on regulated cell death H Flores-Romero, U Ros, AJ García-Sáez International review of cell and molecular biology 351, 197-236, 2020 | 23 | 2020 |
Pore-forming proteins: From defense factors to endogenous executors of cell death H Mesa-Galloso, L Pedrera, U Ros Chemistry and physics of lipids 234, 105026, 2021 | 21 | 2021 |