CRISPR-Cas9 knockin mice for genome editing and cancer modeling RJ Platt, S Chen, Y Zhou, MJ Yim, L Swiech, HR Kempton, JE Dahlman, ... Cell 159 (2), 440-455, 2014 | 1993 | 2014 |
Therapeutic genome editing: prospects and challenges DBT Cox, RJ Platt, F Zhang Nature medicine 21 (2), 121-131, 2015 | 1458 | 2015 |
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening J Joung, S Konermann, JS Gootenberg, OO Abudayyeh, RJ Platt, ... Nature protocols 12 (4), 828-863, 2017 | 1123 | 2017 |
Optical control of mammalian endogenous transcription and epigenetic states S Konermann, MD Brigham, AE Trevino, PD Hsu, M Heidenreich, L Cong, ... Nature 500 (7463), 472-476, 2013 | 1069 | 2013 |
CRISPR-Cas component systems, methods and compositions for sequence manipulation F Zhang US Patent 8,795,965, 2014 | 631 | 2014 |
Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains F Zhang, L Cong, RJ Platt, NE Sanjana, RAN Fei US Patent 8,993,233, 2015 | 552 | 2015 |
Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications F Zhang, RAN Fei US Patent App. 14/104,837, 2014 | 525 | 2014 |
A genome-wide CRISPR screen in primary immune cells to dissect regulatory networks O Parnas, M Jovanovic, TM Eisenhaure, RH Herbst, A Dixit, CJ Ye, ... Cell 162 (3), 675-686, 2015 | 516 | 2015 |
Crispr-cas component systems, methods and compositions for sequence manipulation F Zhang, L Cong, DBT Cox, P Hsu, LIN Shuailiang, RAN Fei, RJ Platt, ... US Patent App. 14/105,035, 2014 | 278 | 2014 |
Efficient CRISPR-Cas9–mediated genome editing in Plasmodium falciparum JC Wagner, RJ Platt, SJ Goldfless, F Zhang, JC Niles Nature methods 11 (9), 915-918, 2014 | 270 | 2014 |
Optogenetic skeletal muscle-powered adaptive biological machines R Raman, C Cvetkovic, SGM Uzel, RJ Platt, P Sengupta, RD Kamm, ... Proceedings of the National Academy of Sciences 113 (13), 3497-3502, 2016 | 268 | 2016 |
Multiplexed genome engineering by Cas12a and CRISPR arrays encoded on single transcripts CC Campa, NR Weisbach, AJ Santinha, D Incarnato, RJ Platt Nature Methods 16 (9), 887-893, 2019 | 228 | 2019 |
AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma RD Chow, CD Guzman, G Wang, F Schmidt, MW Youngblood, L Ye, ... Nature neuroscience 20 (10), 1329-1341, 2017 | 223 | 2017 |
Crispr-cas component systems, methods and compositions for sequence manipulation F Zhang, DO BIKARD, L Cong, DBT Cox, P Hsu, W Jiang, LIN Shauiliang, ... | 223 | 2014 |
Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units SGM Uzel, RJ Platt, V Subramanian, TM Pearl, CJ Rowlands, V Chan, ... Science advances 2 (8), e1501429, 2016 | 204 | 2016 |
Chd8 mutation leads to autistic-like behaviors and impaired striatal circuits RJ Platt, Y Zhou, IM Slaymaker, AS Shetty, NR Weisbach, JA Kim, ... Cell reports 19 (2), 335-350, 2017 | 202 | 2017 |
Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains F Zhang, L Cong, RJ Platt, NE Sanjana, RAN Fei US Patent App. 14/738,398, 2015 | 170 | 2015 |
Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications F Zhang, RJ Platt, G Feng, Y Zhou US Patent App. 14/481,339, 2015 | 165 | 2015 |
Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications F Zhang, RJ Platt, G Feng, Y Zhou US Patent 11,041,173, 2021 | 159 | 2021 |
Transcriptional recording by CRISPR spacer acquisition from RNA F Schmidt, MY Cherepkova, RJ Platt Nature 562 (7727), 380-385, 2018 | 145 | 2018 |