Neurodegeneration and neuroinflammation are linked, but independent of alpha‐synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease P Garcia, W Jürgens‐Wemheuer, O Uriarte Huarte, A Michelucci, ... Glia 70 (5), 935-960, 2022 | 56 | 2022 |
Microglia in health and disease: the strength to be diverse and reactive O Uriarte Huarte, L Richart, MGA Mittelbronn, A Michelucci Frontiers in Cellular Neuroscience 15, 107, 2021 | 55 | 2021 |
Single-cell transcriptomics and in situ morphological analyses reveal microglia heterogeneity across the nigrostriatal pathway O Uriarte Huarte, D Kyriakis, T Heurtaux, K Grzyb, Y Pires-Afonso, ... Frontiers in Immunology 12, 975, 2021 | 47 | 2021 |
Progranulin loss results in sex-dependent dysregulation of the peripheral and central immune system MC Houser, O Uriarte Huarte, RL Wallings, CE Keating, KP MacPherson, ... Frontiers in Immunology 13, 1056417, 2022 | 21 | 2022 |
Single-cell transcriptional profiling and gene regulatory network modeling in Tg2576 mice reveal gender-dependent molecular features preceding Alzheimer-like pathologies M Ali, OU Huarte, T Heurtaux, P Garcia, BP Rodriguez, K Grzyb, R Halder, ... Molecular Neurobiology 61 (2), 541-566, 2024 | 17 | 2024 |
α-Synuclein-activated microglia are implicated in PD pathogenesis H Wood Nature Reviews Neurology 18 (4), 188-188, 2022 | 14 | 2022 |
Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease … S Fixemer, C Ameli, G Hammer, L Salamanca, O Uriarte Huarte, ... Acta Neuropathologica Communications 10 (1), 36, 2022 | 14 | 2022 |
An archaeal compound as a driver of Parkinson’s disease pathogenesis JP Trezzi, V Aho, C Jäger, S Schade, A Janzen, O Hickl, B Kunath, ... Under Review at Nature Portfolio., 2022 | 10 | 2022 |
A leaky gut dysregulates gene networks in the brain associated with immune activation, oxidative stress, and myelination in a mouse model of colitis JS Boles, ME Krueger, JE Jernigan, CL Cole, NK Neighbarger, OU Huarte, ... Brain, Behavior, and Immunity 117, 473-492, 2024 | 7 | 2024 |
Progranulin and GPNMB: interactions in endo-lysosome function and inflammation in neurodegenerative disease DA Gillett, RL Wallings, O Uriarte Huarte, MG Tansey Journal of Neuroinflammation 20 (1), 286, 2023 | 4 | 2023 |
Apomorphine reduces A53T α-synuclein-induced microglial reactivity through activation of NRF2 signalling pathway T Heurtaux, M Kirchmeyer, E Koncina, P Felten, L Richart, ... Cellular and Molecular Neurobiology 42 (8), 2673-2695, 2022 | 4 | 2022 |
Artefactual source of 2-hydroxypyridine P Wilmes, JP Trezzi, V Aho, C Jäger, S Schade, A Janzen, O Hickl, ... | 1 | 2023 |
Understanding microglia–connecting genetic states to functions MG Tansey, OU Huarte Alzheimer's Association International Conference, 2024 | | 2024 |
Peripheral endotoxin exposure in mice activates crosstalk between phagocytes in the brain and periphery J Boles, OU Huarte, MG Tansey | | 2024 |
Locus coeruleus injury modulates ventral midbrain neuroinflammation during DSS-induced colitis MG Tansey, J Boles, J Holt, C Cole, N Neighbarger, N Urs, ... Research Square, 2024 | | 2024 |
Locus coeruleus injury modulates ventral midbrain neuroinflammation during DSS-induced colitis JS Boles, J Holt, CL Cole, NK Neighbarger, NM Urs, OU Huarte, ... bioRxiv, 2024 | | 2024 |
Investigating the role of GPNMB in modulating LPS mediated inflammation in progranulin‐deficient macrophages DA Gillett, N Neighbarger, OU Huarte, MG Tansey Alzheimer's & Dementia 19, e080481, 2023 | | 2023 |
Microfluidics-free single-cell genomics reveals complex central-peripheral immune crosstalk in the mouse brain during peripheral inflammation M Tansey, J Boles, OU Huarte Research Square, 2023 | | 2023 |
An archaeal compound as a driver of Parkinson’s disease pathogenesis P Wilmes, JP Trezzi, V Aho, C Jäger, S Schade, A Janzen, O Hickl, ... | | 2022 |
Concomitant AD and DLB pathologies shape subfield microglia responses in the hippocampus S Fixemer, C Ameli, G Hammer, L Salamanca, OU Huarte, C Schwartz, ... bioRxiv, 2022.01. 06.475218, 2022 | | 2022 |