Toward a physical map of the genome of the nematode Caenorhabditis elegans A Coulson, J Sulston, S Brenner, J Karn Proceedings of the National Academy of Sciences 83 (20), 7821-7825, 1986 | 961 | 1986 |
Nucleotide sequence of tobacco mosaic virus RNA. P Goelet, GP Lomonossoff, PJ Butler, ME Akam, MJ Gait, J Karn Proceedings of the National Academy of Sciences 79 (19), 5818-5822, 1982 | 928 | 1982 |
RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection W Hu, R Kaminski, F Yang, Y Zhang, L Cosentino, F Li, B Luo, ... Proceedings of the National Academy of Sciences 111 (31), 11461-11466, 2014 | 687 | 2014 |
Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitro. C Dingwall, I Ernberg, MJ Gait, SM Green, S Heaphy, J Karn, AD Lowe, ... Proceedings of the National Academy of Sciences 86 (18), 6925-6929, 1989 | 686 | 1989 |
Transcriptional and posttranscriptional regulation of HIV-1 gene expression J Karn, CM Stoltzfus Cold Spring Harbor perspectives in medicine 2 (2), a006916, 2012 | 668 | 2012 |
Tackling tat J Karn Journal of molecular biology 293 (2), 235-254, 1999 | 610 | 1999 |
Periodic charge distributions in the myosin rod amino acid sequence match cross-bridge spacings in muscle AD McLachlan, J Karn Nature 299 (5880), 226-231, 1982 | 560 | 1982 |
HIV‐1 tat protein stimulates transcription by binding to a U‐rich bulge in the stem of the TAR RNA structure. C Dingwall, I Ernberg, MJ Gait, SM Green, S Heaphy, J Karn, AD Lowe, ... The EMBO journal 9 (12), 4145-4153, 1990 | 547 | 1990 |
The structure of the human immunodeficiency virus type-1 TAR RNA reveals principles of RNA recognition by Tat protein F Aboul-ela, J Karn, G Varani Journal of molecular biology 253 (2), 313-332, 1995 | 522 | 1995 |
Novel bacteriophage lambda cloning vector. J Karn, S Brenner, L Barnett, G Cesareni Proceedings of the National Academy of Sciences 77 (9), 5172-5176, 1980 | 505 | 1980 |
Elimination of HIV-1 genomes from human T-lymphoid cells by CRISPR/Cas9 gene editing R Kaminski, Y Chen, T Fischer, E Tedaldi, A Napoli, Y Zhang, J Karn, ... Scientific reports 6 (1), 22555, 2016 | 404 | 2016 |
An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication F Hamy, ER Felder, G Heizmann, J Lazdins, F Aboul-Ela, G Varani, J Karn, ... Proceedings of the National Academy of Sciences 94 (8), 3548-3553, 1997 | 370 | 1997 |
High affinity binding of TAR RNA by the human immunodeficiency virus type-1 tat protein requires base-pairs in the RNA stem and amino acid residues flanking the basic region MJ Churcher, C Lamont, F Hamy, C Dingwall, SM Green, AD Lowe, ... Journal of molecular biology 230 (1), 90-110, 1993 | 361 | 1993 |
Periodic features in the amino acid sequence of nematode myosin rod AD McLachlan, J Karn Journal of molecular biology 164 (4), 605-626, 1983 | 361 | 1983 |
Structure of HIV-1 TAR RNA in the absence of ligands reveals a novel conformation of the trinucleotide bulge F Aboul-ela, J Karn, G Varani Nucleic acids research 24 (20), 3974-3981, 1996 | 339 | 1996 |
Epigenetic silencing of human immunodeficiency virus (HIV) transcription by formation of restrictive chromatin structures at the viral long terminal repeat drives the … R Pearson, YK Kim, J Hokello, K Lassen, J Friedman, M Tyagi, J Karn Journal of virology 82 (24), 12291-12303, 2008 | 333 | 2008 |
Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2 J Friedman, WK Cho, CK Chu, KS Keedy, NM Archin, DM Margolis, J Karn Journal of virology 85 (17), 9078-9089, 2011 | 326 | 2011 |
Ligase/polymerase mediated genetic bit analysis of single nucleotide polymorphisms and its use in genetic analysis T Nikiforov, J Karn, P Goelet US Patent 5,679,524, 1997 | 325 | 1997 |
Establishment of HIV Latency in Primary CD4+ Cells Is due to Epigenetic Transcriptional Silencing and P-TEFb Restriction M Tyagi, RJ Pearson, J Karn Journal of virology 84 (13), 6425-6437, 2010 | 314 | 2010 |
Protein structural domains in the Caenorhabditis elegans unc-54 myosin heavy chain gene are not separated by introns. J Karn, S Brenner, L Barnett Proceedings of the National Academy of Sciences 80 (14), 4253-4257, 1983 | 310 | 1983 |