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| Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down’s syndrome X Altafaj, M Dierssen, C Baamonde, E Martí, J Visa, J Guimerà, M Oset, ... Human molecular genetics 10 (18), 1915-1923, 2001 | 489 | 2001 |
| Dyrk1A Haploinsufficiency Affects Viability and Causes Developmental Delay and Abnormal Brain Morphology in Mice V Fotaki, M Dierssen, S Alcántara, S Martínez, E Martí, C Casas, J Visa, ... Molecular and cellular biology 22 (18), 6636-6647, 2002 | 378 | 2002 |
| Down syndrome: the brain in trisomic mode M Dierssen Nature Reviews Neuroscience 13 (12), 844-858, 2012 | 359 | 2012 |
| Epigallocatechin‐3‐gallate, a DYRK1A inhibitor, rescues cognitive deficits in D own syndrome mouse models and in humans R De la Torre, S De Sola, M Pons, A Duchon, MM de Lagran, M Farré, ... Molecular nutrition & food research 58 (2), 278-288, 2014 | 345 | 2014 |
| Erbb4 deletion from fast-spiking interneurons causes schizophrenia-like phenotypes I Del Pino, C García-Frigola, N Dehorter, JR Brotons-Mas, ... Neuron 79 (6), 1152-1168, 2013 | 324 | 2013 |
| A behavioral assessment of Ts65Dn mice: a putative Down syndrome model RM Escorihuela, A Fernández-Teruel, IF Vallina, C Baamonde, ... Neuroscience letters 199 (2), 143-146, 1995 | 308 | 1995 |
| Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 … R de la Torre, S de Sola, G Hernandez, M Farré, J Pujol, J Rodriguez, ... The Lancet Neurology 15 (8), 801-810, 2016 | 295 | 2016 |
| Potential role of olive oil phenolic compounds in the prevention of neurodegenerative diseases J Rodríguez-Morató, L Xicota, M Fitó, M Farré, M Dierssen, R De la Torre Molecules 20 (3), 4655-4680, 2015 | 271 | 2015 |
| Targeting the endocannabinoid system in the treatment of fragile X syndrome A Busquets-Garcia, M Gomis-González, T Guegan, C Agustín-Pavón, ... Nature medicine 19 (5), 603-607, 2013 | 268 | 2013 |
| Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice M Garriga-Canut, C Agustín-Pavón, F Herrmann, A Sánchez, M Dierssen, ... Proceedings of the National Academy of Sciences 109 (45), E3136-E3145, 2012 | 246 | 2012 |
| Dendritic pathology in mental retardation: from molecular genetics to neurobiology M Dierssen, GJA Ramakers Genes, Brain and Behavior 5, 48-60, 2006 | 244 | 2006 |
| Differential effects of environmental enrichment on behavior and learning of male and female Ts65Dn mice, a model for Down syndrome C Martı́nez-Cué, C Baamonde, M Lumbreras, J Paz, MT Davisson, ... Behavioural brain research 134 (1-2), 185-200, 2002 | 222 | 2002 |
| Hippocampal volume and neuronal number in Ts65Dn mice: a murine model of Down syndrome AM Insausti, M Megıas, D Crespo, LM Cruz-Orive, M Dierssen, TF Vallina, ... Neuroscience letters 253 (3), 175-178, 1998 | 210 | 1998 |
| Impaired short-and long-term memory in Ts65Dn mice, a model for Down syndrome RM Escorihuela, IF Vallina, C Martı́nez-Cué, C Baamonde, M Dierssen, ... Neuroscience letters 247 (2-3), 171-174, 1998 | 200 | 1998 |
| Alterations of neocortical pyramidal cell phenotype in the Ts65Dn mouse model of Down syndrome: effects of environmental enrichment M Dierssen, R Benavides-Piccione, C Martínez-Cué, X Estivill, J Flórez, ... Cerebral cortex 13 (7), 758-764, 2003 | 194 | 2003 |
| Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models I Ferrer, M Barrachina, B Puig, MM De Lagrán, E Martí, J Avila, ... Neurobiology of disease 20 (2), 392-400, 2005 | 191 | 2005 |
| Down syndrome: from understanding the neurobiology to therapy K Gardiner, Y Herault, IT Lott, SE Antonarakis, RH Reeves, M Dierssen Journal of Neuroscience 30 (45), 14943-14945, 2010 | 176 | 2010 |
| Aneuploidy: from a physiological mechanism of variance to Down syndrome M Dierssen, Y Herault, X Estivill Physiological reviews, 2009 | 176 | 2009 |
| Deficits of neuronal density in CA1 and synaptic density in the dentate gyrus, CA3 and CA1, in a mouse model of Down syndrome MA Kurt, MI Kafa, M Dierssen, DC Davies Brain research 1022 (1-2), 101-109, 2004 | 173 | 2004 |
Xavier Estivill MD PhDqGenomics (Quantitative Genomics Laboratories)在 qgenomics.com 的电子邮件经过验证
