Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout OM Woodward, A Köttgen, J Coresh, E Boerwinkle, WB Guggino, ... Proceedings of the National Academy of Sciences 106 (25), 10338-10342, 2009 | 780 | 2009 |
Interaction with podocin facilitates nephrin signaling TB Huber, M Köttgen, B Schilling, G Walz, T Benzing Journal of Biological Chemistry 276 (45), 41543-41546, 2001 | 504 | 2001 |
Primary cilia regulate mTORC1 activity and cell size through Lkb1 C Boehlke, F Kotsis, V Patel, S Braeg, H Voelker, S Bredt, T Beyer, ... Nature cell biology 12 (11), 1115-1122, 2010 | 428 | 2010 |
TRPP2 and TRPV4 form a polymodal sensory channel complex M Köttgen, B Buchholz, MA Garcia-Gonzalez, F Kotsis, X Fu, M Doerken, ... The Journal of cell biology 182 (3), 437-447, 2008 | 423 | 2008 |
Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation M Köttgen, T Benzing, T Simmen, R Tauber, B Buchholz, S Feliciangeli, ... The EMBO journal 24 (4), 705-716, 2005 | 291 | 2005 |
A taste receptor required for the caffeine response in vivo SJ Moon, M Köttgen, Y Jiao, H Xu, C Montell Current biology 16 (18), 1812-1817, 2006 | 271 | 2006 |
Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules OM Woodward, DN Tukaye, J Cui, P Greenwell, LM Constantoulakis, ... Proceedings of the National Academy of Sciences 110 (13), 5223-5228, 2013 | 144 | 2013 |
Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele A Tin, OM Woodward, WHL Kao, CT Liu, X Lu, MA Nalls, D Shriner, ... Human molecular genetics 20 (20), 4056-4068, 2011 | 136 | 2011 |
TRPP2 channels regulate apoptosis through the Ca2+ concentration in the endoplasmic reticulum T Wegierski, D Steffl, C Kopp, R Tauber, B Buchholz, R Nitschke, ... The EMBO journal 28 (5), 490-499, 2009 | 127 | 2009 |
Polycystic kidney disease with hyperinsulinemic hypoglycemia caused by a promoter mutation in phosphomannomutase 2 OR Cabezas, SE Flanagan, H Stanescu, E García-Martínez, R Caswell, ... Journal of the American Society of Nephrology 28 (8), 2529-2539, 2017 | 122 | 2017 |
Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans P Schlosser, Y Li, P Sekula, J Raffler, F Grundner-Culemann, M Pietzner, ... Nature genetics 52 (2), 167-176, 2020 | 109 | 2020 |
ABCG transporters and disease OM Woodward, A Köttgen, M Köttgen The FEBS journal 278 (18), 3215-3225, 2011 | 106 | 2011 |
Phosphorylation by casein kinase 2 induces PACS‐1 binding of nephrocystin and targeting to cilia B Schermer, K Höpker, H Omran, C Ghenoiu, M Fliegauf, A Fekete, ... The EMBO journal 24 (24), 4415-4424, 2005 | 105 | 2005 |
Eomes and Brachyury control pluripotency exit and germ-layer segregation by changing the chromatin state J Tosic, GJ Kim, M Pavlovic, CM Schröder, SL Mersiowsky, M Barg, ... Nature cell biology 21 (12), 1518-1531, 2019 | 102 | 2019 |
TRPP2 and autosomal dominant polycystic kidney disease M Köttgen Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1772 (8), 836-850, 2007 | 102 | 2007 |
P2Y6 receptor mediates colonic NaCl secretion via differential activation of cAMP-mediated transport M Köttgen, T Löffler, C Jacobi, R Nitschke, H Pavenstädt, R Schreiber, ... The Journal of clinical investigation 111 (3), 371-379, 2003 | 102 | 2003 |
OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum Y Wang, X Fu, S Gaiser, M Kottgen, A Kramer-Zucker, G Walz, ... Journal of Biological Chemistry 282 (50), 36561-36570, 2007 | 94 | 2007 |
Cilia‐localized LKB 1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney A Viau, F Bienaimé, K Lukas, AP Todkar, M Knoll, TA Yakulov, A Hofherr, ... The EMBO journal 37 (15), e98615, 2018 | 86 | 2018 |
Subcellular localization and trafficking of polycystins M Köttgen, G Walz Pflügers Archiv 451, 286-293, 2005 | 86 | 2005 |
Interaction of 14-3-3 protein with regulator of G protein signaling 7 is dynamically regulated by tumor necrosis factor-α T Benzing, M Ko, M Johnson, B Schermer, H Zentgraf, G Walz, E Kim Journal of Biological Chemistry 277 (36), 32954-32962, 2002 | 80 | 2002 |