Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing S Sadegh, J Matschinske, DB Blumenthal, G Galindez, T Kacprowski, ... Nature communications 11 (1), 3518, 2020 | 170 | 2020 |
Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research F Hufsky, K Lamkiewicz, A Almeida, A Aouacheria, C Arighi, A Bateman, ... Briefings in bioinformatics 22 (2), 642-663, 2021 | 149 | 2021 |
Lessons from the COVID-19 pandemic for advancing computational drug repurposing strategies G Galindez, J Matschinske, TD Rose, S Sadegh, M Salgado-Albarrán, ... Nature Computational Science 1 (1), 33-41, 2021 | 109 | 2021 |
Network medicine for disease module identification and drug repurposing with the NeDRex platform S Sadegh, J Skelton, E Anastasi, J Bernett, DB Blumenthal, G Galindez, ... Nature communications 12 (1), 6848, 2021 | 66 | 2021 |
NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype MH Elbatreek, S Sadegh, E Anastasi, E Guney, C Nogales, T Kacprowski, ... PLoS Biology 18 (11), e3000885, 2020 | 36 | 2020 |
Network-based approaches for modeling disease regulation and progression G Galindez, S Sadegh, J Baumbach, T Kacprowski, M List Computational and Structural Biotechnology Journal 21, 780-795, 2023 | 15 | 2023 |
Robust disease module mining via enumeration of diverse prize-collecting Steiner trees J Bernett, D Krupke, S Sadegh, J Baumbach, SP Fekete, T Kacprowski, ... Bioinformatics 38 (6), 1600-1606, 2022 | 14 | 2022 |
Network medicine-based unbiased disease modules for drug and diagnostic target identification in ROSopathies C Nogales, AGB Grønning, S Sadegh, J Baumbach, HHHW Schmidt Reactive Oxygen Species: Network Pharmacology and Therapeutic Applications …, 2021 | 9 | 2021 |
Individuating possibly repurposable drugs and drug targets for COVID-19 treatment through hypothesis-driven systems medicine using CoVex J Matschinske, M Salgado-Albarrán, S Sadegh, D Bongiovanni, ... Assay and drug development technologies 18 (8), 348-355, 2020 | 8 | 2020 |
Lacking mechanistic disease definitions and corresponding association data hamper progress in network medicine and beyond S Sadegh, J Skelton, E Anastasi, A Maier, K Adamowicz, A Möller, ... Nature Communications 14 (1), 1662, 2023 | 7 | 2023 |
Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing. Nat Commun 11: 3518 S Sadegh, J Matschinske, DB Blumenthal, G Galindez, T Kacprowski, ... | 7 | 2020 |
Drugst. One—a plug-and-play solution for online systems medicine and network-based drug repurposing A Maier, M Hartung, M Abovsky, K Adamowicz, GD Bader, S Baier, ... Nucleic Acids Research, gkae388, 2024 | 6 | 2024 |
Drugst A Maier, M Hartung, M Abovsky, K Adamowicz, GD Bader, S Baier, ... One–A plug-and-play solution for online systems medicine and network-based …, 2023 | 6 | 2023 |
NeDRex-an integrative and interactive network medicine platform for drug repurposing S Sadegh, J Skelton, E Anastasi, DB Blumenthal, A Maier, G Galindez, ... RExPO22, 2022 | 2 | 2022 |
Randomization strategies affect motif significance analysis in TF-miRNA-gene regulatory networks S Sadegh, M Nazarieh, C Spaniol, V Helms Journal of Integrative Bioinformatics 14 (2), 20170017, 2017 | 2 | 2017 |
A plug-and-play solution to bring network exploration and drug repurposing to biomedical web platforms M Hartung, A Maier, S Sadegh, J Matschinske, M List, OA Zolotareva, ... RExPO22, 2022 | 1 | 2022 |
Network pharmacology drug repurposing strategy for neurovascular diseases AI Casas, C Nogales, MH Elbatreek, S Sadegh, E Anastasi, J Skelton, ... RExPO22, 2022 | 1 | 2022 |
Streamlining and generalizing network-based drug discovery with NeDRex and Drugst. One FM Delgado-Chaves, S Sadegh, J Skelton, A Maier, M Hartung, ... RExPO23, 2023 | | 2023 |
Targeting infectious diseases: The CoVex example S Sadegh, J Matschinske, DB Blumenthal, G Galindez, T Kacprowski, ... RExPO22, 2022 | | 2022 |
Network modules as molecular disease definitions for mechanism-based endotyping anddrug repurposing C Nogales Calvo, AI Casas, A Petraina, M Pacheco Pachado, S Sadegh, ... RExPO22, 2022 | | 2022 |