Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules B Nabet, FM Ferguson, BKA Seong, M Kuljanin, AL Leggett, ML Mohardt, ... Nature communications 11 (1), 4687, 2020 | 190 | 2020 |
TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma BKA Seong, NV Dharia, S Lin, KA Donovan, S Chong, A Robichaud, ... Cancer cell 39 (9), 1262-1278. e7, 2021 | 78 | 2021 |
STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma B Adane, G Alexe, BKA Seong, D Lu, EE Hwang, D Hnisz, CA Lareau, ... Cancer cell 39 (6), 827-844. e10, 2021 | 73 | 2021 |
SATB2 enhances migration and invasion in osteosarcoma by regulating genes involved in cytoskeletal organization BKA Seong, J Lau, T Adderley, L Kee, D Chaukos, M Pienkowska, ... Oncogene 34 (27), 3582-3592, 2015 | 57 | 2015 |
An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML S Lin, C Larrue, NK Scheidegger, BKA Seong, NV Dharia, M Kuljanin, ... Cancer discovery 12 (2), 432-449, 2022 | 52 | 2022 |
A metastatic mouse model identifies genes that regulate neuroblastoma metastasis BKA Seong, KE Fathers, R Hallett, CK Yung, LD Stein, S Mouaaz, L Kee, ... Cancer research 77 (3), 696-706, 2017 | 40 | 2017 |
Biology and therapy of dominant fusion oncoproteins involving transcription factor and chromatin regulators in sarcomas JA Perry, BKA Seong, K Stegmaier Annual Review of Cancer Biology 3 (1), 299-321, 2019 | 38 | 2019 |
Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma B Jiang, J Jiang, IH Kaltheuner, AB Iniguez, K Anand, FM Ferguson, ... European Journal of Medicinal Chemistry 221, 113481, 2021 | 33 | 2021 |
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma DY Lu, JM Ellegast, KN Ross, CF Malone, S Lin, NW Mabe, NV Dharia, ... Nature Cell Biology 25 (2), 285-297, 2023 | 23 | 2023 |
Gene fusions create partner and collateral dependencies essential to cancer cell survival R Gillani, BKA Seong, J Crowdis, JR Conway, NV Dharia, S Alimohamed, ... Cancer research 81 (15), 3971-3984, 2021 | 16 | 2021 |
Transcript signatures that predict outcome and identify targetable pathways in MYCN-amplified neuroblastoma RM Hallett, ABK Seong, DR Kaplan, MS Irwin Molecular oncology 10 (9), 1461-1472, 2016 | 16 | 2016 |
Vitamin D receptor activation attenuates hippo pathway effectors and cell survival in metastatic neuroblastoma Y Ladumor, BKA Seong, R Hallett, I Valencia-Sama, T Adderley, Y Wang, ... Molecular Cancer Research 20 (6), 895-908, 2022 | 6 | 2022 |
The absence of a novel intron 19-retaining ALK transcript (ALK-I19) and MYCN amplification correlates with an excellent clinical outcome in neuroblastoma patients A Alshareef, MS Irwin, N Gupta, HF Zhang, M Haque, SD Findlay, ... Oncotarget 9 (12), 10698, 2018 | 2 | 2018 |
SLC5A3 Transports Myo-Inositol to Support the Growth of Acute Myeloid Leukemia S Lin, NK Scheidegger, G Alexe, BKA Seong, NV Dharia, C Wechsler, ... Blood 138, 3319, 2021 | 1 | 2021 |
EWS-FLI1-driven upregulation of UGT3A2 unlocks drug sensitivity pathway in Ewing sarcoma O Olaoye, C Harrington, K Ross, BKA Seong, L de Waal, J Qi, J Roth, ... Cancer Research 84 (6_Supplement), 3244-3244, 2024 | | 2024 |
Abstract B021: Long non-coding RNAs that are required for robust cell growth in ewing Sarcoma MC Briones Martin del Campo, A Lee, M Horlbeck, T Dinh, ... Clinical Cancer Research 28 (18_Supplement), B021-B021, 2022 | | 2022 |
An In Vivo CRISPR Screening Platform to Identify New Therapeutic Targets in AML S Lin, C Larrue, NK Scheidegger, BKA Seong, NV Dharia, C Wechsler, ... Blood 138, 266, 2021 | | 2021 |
STAG2 loss reshapes oncogenic enhancer-promoter looping in Ewing sarcoma B Adane, G Alexe, BKA Seong, D Lu, EE Hwang, D Hnisz, CA Lareau, ... Elsevier BV, 2021 | | 2021 |
Abstract B50: Targeting EWS/FLI fusion oncoprotein stability/degradation in Ewing sarcoma BKA Seong, S Lin, K Donovan, A Robichaud, B Stolte, E Wang, N Dharia, ... Cancer Research 80 (14_Supplement), B50-B50, 2020 | | 2020 |
Targeting EWS/FLI fusion oncoprotein stability/degradation in Ewing sarcoma BKA Seong, S Lin, K Donovan, A Robichaud, B Stolte, E Wang, N Dharia, ... CANCER RESEARCH 80 (14), 105-106, 2020 | | 2020 |