Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy, 1-382, 2021 | 10842 | 2021 |
Cellular senescence: defining a path forward V Gorgoulis, PD Adams, A Alimonti, DC Bennett, O Bischof, C Bishop, ... Cell 179 (4), 813-827, 2019 | 1928 | 2019 |
Cellular senescence mediates fibrotic pulmonary disease MJ Schafer, TA White, K Iijima, AJ Haak, G Ligresti, EJ Atkinson, AL Oberg, ... Nature communications 8 (1), 14532, 2017 | 1268 | 2017 |
Feedback between p21 and reactive oxygen production is necessary for cell senescence JF Passos, G Nelson, C Wang, T Richter, C Simillion, CJ Proctor, S Miwa, ... Molecular systems biology 6 (1), 347, 2010 | 1000 | 2010 |
Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence G Hewitt, D Jurk, FDM Marques, C Correia-Melo, T Hardy, A Gackowska, ... Nature communications 3 (1), 708, 2012 | 888 | 2012 |
Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease LTJ Hickson, LGPL Prata, SA Bobart, TK Evans, N Giorgadze, SK Hashmi, ... EBioMedicine 47, 446-456, 2019 | 858 | 2019 |
Cellular senescence drives age-dependent hepatic steatosis M Ogrodnik, S Miwa, T Tchkonia, D Tiniakos, CL Wilson, A Lahat, CP Day, ... Nature communications 8 (1), 15691, 2017 | 806 | 2017 |
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence JF Passos, G Saretzki, S Ahmed, G Nelson, T Richter, H Peters, I Wappler, ... PLoS biology 5 (5), e110, 2007 | 783 | 2007 |
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ... Nature communications 5 (1), 4172, 2014 | 777 | 2014 |
Mitochondria are required for pro‐ageing features of the senescent phenotype C Correia‐Melo, FDM Marques, R Anderson, G Hewitt, R Hewitt, J Cole, ... The EMBO journal 35 (7), 724-742, 2016 | 639 | 2016 |
Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress S Ahmed, JF Passos, MJ Birket, T Beckmann, S Brings, H Peters, ... Journal of cell science 121 (7), 1046-1053, 2008 | 546 | 2008 |
Lysosome-mediated processing of chromatin in senescence A Ivanov, J Pawlikowski, I Manoharan, J van Tuyn, DM Nelson, TS Rai, ... Journal of Cell Biology 202 (1), 129-143, 2013 | 519 | 2013 |
Obesity-induced cellular senescence drives anxiety and impairs neurogenesis M Ogrodnik, Y Zhu, LGP Langhi, T Tchkonia, P Krüger, E Fielder, ... Cell metabolism 29 (5), 1061-1077. e8, 2019 | 432 | 2019 |
DNA damage in telomeres and mitochondria during cellular senescence: is there a connection? JF Passos, G Saretzki, T von Zglinicki Nucleic acids research 35 (22), 7505-7513, 2007 | 402 | 2007 |
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence R Anderson, A Lagnado, D Maggiorani, A Walaszczyk, E Dookun, ... The EMBO journal 38 (5), e100492, 2019 | 393 | 2019 |
Mitochondrial inner membrane permeabilisation enables mt DNA release during apoptosis JS Riley, G Quarato, C Cloix, J Lopez, J O'Prey, M Pearson, J Chapman, ... The EMBO journal 37 (17), e99238, 2018 | 379 | 2018 |
Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition BI Pereira, OP Devine, M Vukmanovic-Stejic, ES Chambers, ... Nature communications 10 (1), 2387, 2019 | 357 | 2019 |
Telomeres and cell senescence-size matters not S Victorelli, JF Passos EBioMedicine 21, 14-20, 2017 | 349 | 2017 |
Stress, cell senescence and organismal ageing JP de Magalhães, JF Passos Mechanisms of ageing and development 170, 2-9, 2018 | 342 | 2018 |
Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells G Saretzki, T Walter, S Atkinson, JF Passos, B Bareth, WN Keith, ... Stem cells 26 (2), 455-464, 2008 | 310 | 2008 |