An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants KK Chan, TJC Tan, KK Narayanan, E Procko Science Advances 7 (8), eabf1738, 2021 | 131 | 2021 |
Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain TJC Tan, M Yuan, K Kuzelka, GC Padron, JR Beal, X Chen, Y Wang, ... Nature Communications 12, 1-10, 2021 | 52 | 2021 |
Probing the biophysical constraints of SARS-CoV-2 spike N-terminal domain using deep mutational scanning WO Ouyang, TJC Tan, R Lei, G Song, C Kieffer, R Andrabi, KA Matreyek, ... Science Advances 8 (47), eadd7221, 2022 | 18 | 2022 |
High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike TJC Tan, Z Mou, R Lei, WO Ouyang, M Yuan, G Song, R Andrabi, ... Nature Communications 14, 2003, 2023 | 17 | 2023 |
Molecular analysis of a public cross-neutralizing antibody response to SARS-CoV-2 M Yuan, Y Wang, H Lv, TJC Tan, IA Wilson, NC Wu Cell Reports 41 (7), 2022 | 15 | 2022 |
The evolutionary potential of influenza A virus hemagglutinin is highly constrained by epistatic interactions with neuraminidase T Liu, Y Wang, TJC Tan, NC Wu, CB Brooke Cell Host & Microbe 30 (10), 1363-1369. e4, 2022 | 15 | 2022 |
Mutational fitness landscape of human influenza H3N2 neuraminidase R Lei, AH Garcia, TJC Tan, QW Teo, Y Wang, X Zhang, S Luo, SK Nair, ... Cell reports 42 (1), 2023 | 11 | 2023 |
Virus-induced activation of the rac1 protein at the site of respiratory syncytial virus assembly is a requirement for virus particle assembly on infected cells LI Ravi, TJ Tan, BH Tan, RJ Sugrue Virology 557, 86-99, 2021 | 11 | 2021 |
Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH T Schulte, MD Panas, X Han, L Williams, N Kedersha, JS Fleck, TJC Tan, ... Open Biology 13 (5), 220369, 2023 | 9* | 2023 |
Egg-adaptive mutations of human influenza H3N2 virus are contingent on natural evolution W Liang, TJC Tan, Y Wang, H Lv, Y Sun, R Bruzzone, CKP Mok, NC Wu PLoS pathogens 18 (9), e1010875, 2022 | 9 | 2022 |
Arabidopsis thaliana G3BP Ortholog Rescues Mammalian Stress Granule Phenotype across Kingdoms H Reuper, B Götte, L Williams, TJC Tan, GM McInerney, MD Panas, ... International Journal of Molecular Sciences 22 (12), 6287, 2021 | 7 | 2021 |
Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase R Lei, W Kim, H Lv, Z Mou, MJ Scherm, AJ Schmitz, JS Turner, TJC Tan, ... Immunity 56 (11), 2621-2634. e6, 2023 | 5 | 2023 |
An explainable language model for antibody specificity prediction using curated influenza hemagglutinin antibodies Y Wang, H Lv, R Lei, YH Yeung, IR Shen, D Choi, QW Teo, TJC Tan, ... bioRxiv, 2023 | 4 | 2023 |
Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase R Lei, TJC Tan, A Hernandez Garcia, Y Wang, M Diefenbacher, C Teo, ... Nature communications 13, 6443, 2022 | 4 | 2022 |
Interactions between Influenza A Virus Nucleoprotein and Gene Segment Untranslated Regions Facilitate Selective Modulation of Viral Gene Expression M Diefenbacher, TJC Tan, DLV Bauer, BM Stadtmueller, NC Wu, ... Journal of Virology, e00205-22, 2022 | 4 | 2022 |
Widespread impact of immunoglobulin V gene allelic polymorphisms on antibody reactivity M Yuan, Z Feng, H Lv, N So, IR Shen, TJC Tan, QW Teo, WO Ouyang, ... bioRxiv, 2023.06. 06.543969, 2023 | 2 | 2023 |
Natural variation in neuraminidase activity influences the evolutionary potential of the seasonal H1N1 lineage hemagglutinin T Liu, WK Reiser, TJC Tan, H Lv, J Rivera-Cardona, K Heimburger, ... Virus Evolution, veae046, 2024 | | 2024 |
Epistasis mediates the evolution of the receptor binding mode in recent human H3N2 hemagglutinin R Lei, W Liang, WO Ouyang, A Hernandez Garcia, C Kikuchi, S Wang, ... Nature Communications 15 (1), 5175, 2024 | | 2024 |
Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning R Lei, E Qing, A Odle, M Yuan, CD Gunawardene, TJC Tan, N So, ... Nature Communications 15 (1), 4056, 2024 | | 2024 |
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike TJC Tan, AK Verma, A Odle, R Lei, DK Meyerholz, KA Matreyek, ... Proceedings of the National Academy of Sciences 121 (15), e2317222121, 2024 | | 2024 |