IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer FR Greten, L Eckmann, TF Greten, JM Park, ZW Li, LJ Egan, MF Kagnoff, ... Cell 118 (3), 285-296, 2004 | 3249 | 2004 |
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer S Grivennikov, E Karin, J Terzic, D Mucida, GY Yu, S Vallabhapurapu, ... Cancer cell 15 (2), 103-113, 2009 | 2474 | 2009 |
A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. HC Jung, L Eckmann, SK Yang, A Panja, J Fierer, ... The Journal of clinical investigation 95 (1), 55-65, 1995 | 1487 | 1995 |
Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth SI Grivennikov, K Wang, D Mucida, CA Stewart, B Schnabl, D Jauch, ... Nature 491 (7423), 254-258, 2012 | 1393 | 2012 |
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface S Vaishnava, CL Behrendt, AS Ismail, L Eckmann, LV Hooper Proceedings of the National Academy of Sciences 105 (52), 20858-20863, 2008 | 1209 | 2008 |
Nod2 Mutation in Crohn's Disease Potentiates NF-κB Activity and IL-1β Processing S Maeda, LC Hsu, H Liu, LA Bankston, M Iimura, MF Kagnoff, L Eckmann, ... Science 307 (5710), 734-738, 2005 | 1002 | 2005 |
Expression and regulation of the human β-defensins hBD-1 and hBD-2 in intestinal epithelium DA O’Neil, EM Porter, D Elewaut, GM Anderson, L Eckmann, T Ganz, ... The Journal of Immunology 163 (12), 6718-6724, 1999 | 878 | 1999 |
Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry L Eckmann, MF Kagnoff, J Fierer Infection and immunity 61 (11), 4569-4574, 1993 | 861 | 1993 |
Epithelial cells as sensors for microbial infection. MF Kagnoff, L Eckmann The Journal of clinical investigation 100 (1), 6-10, 1997 | 808 | 1997 |
Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells J Lee, JH Mo, K Katakura, I Alkalay, AN Rucker, YT Liu, HK Lee, C Shen, ... Nature cell biology 8 (12), 1327-1336, 2006 | 777 | 2006 |
NF-κB is a negative regulator of IL-1β secretion as revealed by genetic and pharmacological inhibition of IKKβ FR Greten, MC Arkan, J Bollrath, LC Hsu, J Goode, C Miething, ... Cell 130 (5), 918-931, 2007 | 758 | 2007 |
Secretion of proinflammatory cytokines by epithelial cells in response to Chlamydia infection suggests a central role for epithelial cells in chlamydial pathogenesis. SJ Rasmussen, L Eckmann, AJ Quayle, L Shen, YX Zhang, DJ Anderson, ... The Journal of clinical investigation 99 (1), 77-87, 1997 | 678 | 1997 |
Differential cytokine expression by human intestinal epithelial cell lines: regulated expression of interleukin 8 L Eckmann, HC Jung, C Schürer-Maly, A Panja, E Morzycka-Wroblewska, ... Gastroenterology 105 (6), 1689-1697, 1993 | 650 | 1993 |
Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis C Zaph, AE Troy, BC Taylor, LD Berman-Booty, KJ Guild, Y Du, EA Yost, ... Nature 446 (7135), 552-556, 2007 | 639 | 2007 |
Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease YI Duan, C Llorente, S Lang, K Brandl, H Chu, L Jiang, RC White, ... Nature 575 (7783), 505-511, 2019 | 600 | 2019 |
Toll-like receptor 9–induced type I IFN protects mice from experimental colitis K Katakura, J Lee, D Rachmilewitz, G Li, L Eckmann, E Raz The Journal of clinical investigation 115 (3), 695-702, 2005 | 526 | 2005 |
A NOD2–NALP1 complex mediates caspase-1-dependent IL-1β secretion in response to Bacillus anthracis infection and muramyl dipeptide LC Hsu, SR Ali, S McGillivray, PH Tseng, S Mariathasan, EW Humke, ... Proceedings of the National Academy of Sciences 105 (22), 7803-7808, 2008 | 495 | 2008 |
The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4 LC Hsu, J Mo Park, K Zhang, JL Luo, S Maeda, RJ Kaufman, L Eckmann, ... Nature 428 (6980), 341-345, 2004 | 468 | 2004 |
NF-κB is a central regulator of the intestinal epithelial cell innate immune response induced by infection with enteroinvasive bacteria D Elewaut, JA DiDonato, J Mogg Kim, F Truong, L Eckmann, MF Kagnoff The Journal of Immunology 163 (3), 1457-1466, 1999 | 439 | 1999 |
Differential and regulated expression of CXC, CC, and C-chemokines by human colon epithelial cells SK Yang, L Eckmann, A Panja, MF Kagnoff Gastroenterology 113 (4), 1214-1223, 1997 | 422 | 1997 |