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Emmanuel Israel Edache (Ph.D)
Emmanuel Israel Edache (Ph.D)
Department of Pure and Applied Chemistry, University of Maiduguri, Maiduguri, Borno State, Nigeria
在 abu.edu.ng 的电子邮件经过验证
标题
引用次数
引用次数
年份
Structure-based simulated scanning of rheumatoid arthritis inhibitors: 2D-QSAR, 3D-QSAR, docking, molecular dynamics simulation, and lipophilicity indices calculation
EI Edache, A Uzairu, PA Mamza, GA Shallangwa
Scientific African 15, e01088, 2022
262022
QSAR, homology modeling, and docking simulation on SARS-CoV-2 and pseudomonas aeruginosa inhibitors, ADMET, and molecular dynamic simulations to find a possible oral lead candidate
EI Edache, A Uzairu, PA Mamza, GA Shallangwa
Journal of Genetic Engineering and Biotechnology 20 (1), 88, 2022
252022
A Semi-empirical based QSAR study of indole𝜷-Diketo acid, Diketo acid and Carboxamide Derivativesas potent HIV-1 agent Using Quantum Chemical descriptors
EI Edache, AJ Uttu, A Oluwaseye, H Samuel, A Abduljelil
IOSR Journal of Applied Chemistry (IOSR-JAC) 8 (11), 12-20, 2015
232015
A comparative QSAR analysis, 3D-QSAR, molecular docking and molecular design of iminoguanidine-based inhibitors of HemO: A rational approach to antibacterial drug design
EI Edache, A Uzairu, PA Mamza, GA Shallangwa
Journal of Drugs and Pharmaceutical Science 4 (3), 21-36, 2020
172020
Docking Simulations and Virtual Screening to find Novel Ligands for T3S in Yersinia pseudotuberculosis YPIII, A drug target for type III secretion (T3S) in the Gram-negative …
EI Edache, U Adamu, PA Mamza, SA Gideon
Chemical Review and Letters 4 (3), 130-144, 2021
162021
Methimazole and propylthiouracil design as a drug for anti-graves' disease: Structural studies, Hirshfeld surface analysis, DFT calculations, molecular docking, molecular …
EI Edache, A Uzairu, PA Mamza, GA Shallangwa, M Azam, K Min
Journal of Molecular Structure 1289, 135913, 2023
142023
Theoretical Investigation of the Cooperation of Iminoguanidine with the Enzymes-Binding Domain of Covid-19 and Bacterial Lysozyme Inhibitors and their Pharmacokinetic Properties
EI Edache, A Uzairu, PA Mamza, GA Shallangwa
Journal of Mexican Chemical Society 66 (4), 513-542, 2022
142022
Prediction of HemO Inhibitors Based on Iminoguanidine using QSAR, 3DQSAR Study, Molecular Docking, Molecular Dynamic Simulation and ADMET
EI Edache, A Uzairu, PA Mamza, GA Shallangwa
Journal of Drug Design and Discovery Research 1 (2), 36-52, 2020
142020
Quantitative structure-activity relationship analysis of the anti-tyrosine activity of some tetraketone and benzyl-benzoate derivatives based on genetic algorithm-multiple …
EI Edache, DE Arthur, U Abdulfatai
Journal of Chemistry and Materials Research 6 (1), 3-13, 2016
142016
Cheminformatics-based discovery of new organoselenium compounds with potential for the treatment of cutaneous and visceral leishmaniasis
FA Ugbe, GA Shallangwa, A Uzairu, I Abdulkadir, EI Edache, AI Al-Megrin, ...
Journal of Biomolecular Structure and Dynamics, 2023
132023
Virtual screening, pharmacokinetics, and molecular dynamics simulations studies to identify potent approved drugs for Chlamydia trachomatis treatment
EI Edache, A Uzairu, GA Shallangwa, PA Mamza
Future Journal of Pharmaceutical Sciences 7, 1-22, 2021
122021
QSAR and Molecular Docking Analysis of Substituted Tetraketone and Benzyl-benzoate Analogs as Anti-tyrosine: A Novel Approach to anti-tyrosine kinase Drug Design and Discovery
EI Edache, H Samuel, YI Sulyman, O Arinze, OI Ayine
Chemistry Research Journal 5 (6), 79-100, 2020
122020
Docking and Virtual Screening Studies of Tetraketone Derivatives as Tyrosine Kinase (EGFR) Inhibitors: A Rational Approach to Anti-Fungi Drug Design
S Shafiu, EI Edache, U Sani, M Abatyough
Journal of Pharmaceutical and Medicinal Research 3 (1), 78-80, 2017
112017
In-silico discovery and simulated selection of multi-target Anti-HIV-1 inhibitors
EI Edache, HU Hambali, DE Arthur, A Oluwaseye, OC Chinweuba
Int Res J Pure Appl Chem 11 (1), 1-15, 2016
112016
3D-QSAR, Molecular Docking, Molecular Dynamics Simulations and Structural Studies of Some Selected Inhibitors of the Glycoprotein (GPC) of Lassa Virus
EI Edache, HA Dawi, FA Ugbe
Journal of Applied Organometallic Chemistry 3 (3), 224-244, 2023
102023
Investigation of 5, 6-dihydro-2-pyrones derivatives as potent anti-HIV agents inhibitors
EI Edache, A Uzairu, SE Abeche
J Comput Methods Mol Des 5 (3), 135-149, 2015
102015
Evaluation of dimedone-derived compounds as inhibitors against human colon cancer: Insights from 2D-QSAR, ADMET prediction, Osiris, Molinspiration, and molecular modeling
K Mkhayar, K Elkhattabi, R Elkhalabi, R Haloui, O Daoui, EI Edache, ...
Chinese Journal of Analytical Chemistry 51 (11), 100330, 2023
92023
(S)-N-(4-Carbamoylphenyl)-8-Cyclopropyl-7-(Naphthalen-1-ylmethyl)-5-Oxo-2, 3-Dihydro-5H-Thiazolo [3, 2-a] Pyridine-3-Carboxamide, A Better Inhibitor of SARS-Cov-2 Spike …
EI Edache, A Uzairu, GA Shallangwa, PA Mamza
Advanced Journal of Chemistry, Section A 6 (1), 17-30, 2023
92023
Computational evaluation of the inhibitory potential of some urea, thiourea, and selenourea derivatives of diselenides against leishmaniasis: 2D-QSAR, pharmacokinetics …
FA Ugbe, EI Edache, SE Adeniji, DE Arthur, A Ajala, SN Adawara, S Ejeh, ...
Journal of Molecular Structure 1302, 137473, 2024
82024
Combining Docking, Molecular Dynamics Simulations, AD-MET pharmacokinetics properties, and MMGBSA calculations to create specialized protocols for running effective virtual …
E Edache, A Uzairu, PA Mamza, GA Shallangwa, FH Yagin, ...
Frontiers in Molecular Biosciences 10, 1254230, 2023
72023
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