Trapping of PARP1 and PARP2 by clinical PARP inhibitors J Murai, SYN Huang, BB Das, A Renaud, Y Zhang, JH Doroshow, J Ji, ... Cancer research 72 (21), 5588-5599, 2012 | 2148 | 2012 |
Tyrosyl-DNA-phosphodiesterases (tdp1 and tdp2) Y Pommier, NH Shar-yin, R Gao, BB Das, J Murai, C Marchand DNA repair 19, 114-129, 2014 | 346 | 2014 |
Camptothecin induced mitochondrial dysfunction leading to programmed cell death in unicellular hemoflagellate Leishmania donovani N Sen, BB Das, A Ganguly, T Mukherjee, G Tripathi, S Bandyopadhyay, ... Cell Death & Differentiation 11 (8), 924-936, 2004 | 295 | 2004 |
Ataxia telangiectasia mutated activation by transcription‐and topoisomerase I‐induced DNA double‐strand breaks O Sordet, CE Redon, J Guirouilh‐Barbat, S Smith, S Solier, C Douarre, ... EMBO reports 10 (8), 887-893, 2009 | 264 | 2009 |
PARP1–TDP1 coupling for the repair of topoisomerase I–induced DNA damage DBB al Nucleic Acids Res., 2014 | 225 | 2014 |
Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells J Murai, NH Shar-yin, BB Das, TS Dexheimer, S Takeda, Y Pommier Journal of Biological Chemistry 287 (16), 12848-12857, 2012 | 192 | 2012 |
Mitochondria-dependent reactive oxygen species-mediated programmed cell death induced by 3, 3′-diindolylmethane through inhibition of F0F1-ATP synthase in unicellular … A Roy, A Ganguly, S BoseDasgupta, BB Das, C Pal, P Jaisankar, ... Molecular Pharmacology 74 (5), 1292-1307, 2008 | 183 | 2008 |
Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA‐PK BB Das, S Antony, S Gupta, TS Dexheimer, CE Redon, S Garfield, ... The EMBO journal 28 (23), 3667-3680, 2009 | 172 | 2009 |
Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria BB Das, TS Dexheimer, K Maddali, Y Pommier Proceedings of the National Academy of Sciences 107 (46), 19790-19795, 2010 | 158 | 2010 |
Camptothecin-induced imbalance in intracellular cation homeostasis regulates programmed cell death in unicellular hemoflagellate Leishmania donovani N Sen, BB Das, A Ganguly, T Mukherjee, S Bandyopadhyay, ... Journal of Biological Chemistry 279 (50), 52366-52375, 2004 | 157 | 2004 |
Apoptosis is induced in leishmanial cells by a novel protein kinase inhibitor withaferin A and is facilitated by apoptotic topoisomerase I–DNA complex N Sen, B Banerjee, BB Das, A Ganguly, T Sen, S Pramanik, ... Cell Death & Differentiation 14 (2), 358-367, 2007 | 130 | 2007 |
Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism C Douarre, C Sourbier, I Dalla Rosa, B Brata Das, CE Redon, H Zhang, ... PloS one 7 (7), e41094, 2012 | 119 | 2012 |
Betulinic acid, a catalytic inhibitor of topoisomerase I, inhibits reactive oxygen species–mediated apoptotic topoisomerase I–DNA cleavable complex formation in prostate cancer … A Ganguly, B Das, A Roy, N Sen, SB Dasgupta, S Mukhopadhayay, ... Cancer research 67 (24), 11848-11858, 2007 | 115 | 2007 |
Reconstitution and functional characterization of the unusual bi-subunit type I DNA topoisomerase from Leishmania donovani BB Das, N Sen, A Ganguly, HK Majumder FEBS letters 565 (1-3), 81-88, 2004 | 94 | 2004 |
Differential induction of Leishmania donovani bi-subunit topoisomerase I–DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin … BB Das, N Sen, A Roy, SB Dasgupta, A Ganguly, BC Mohanta, B Dinda, ... Nucleic acids research 34 (4), 1121-1132, 2006 | 88 | 2006 |
The caspase-independent algorithm of programmed cell death in Leishmania induced by baicalein: the role of LdEndoG, LdFEN-1 and LdTatD as a DNA ‘degradesome’ S BoseDasgupta, BB Das, S Sengupta, A Ganguly, A Roy, S Dey, ... Cell Death & Differentiation 15 (10), 1629-1640, 2008 | 83 | 2008 |
Design, synthesis and evaluation of thiohydantoin derivatives as potent topoisomerase I (Top1) inhibitors with anticancer activity P Majumdar, C Bathula, SM Basu, SK Das, R Agarwal, S Hati, A Singh, ... European journal of medicinal chemistry 102, 540-551, 2015 | 78 | 2015 |
Poly (ADP-ribose) polymers regulate DNA topoisomerase I (Top1) nuclear dynamics and camptothecin sensitivity in living cells SK Das, I Rehman, A Ghosh, S Sengupta, P Majumdar, B Jana, BB Das Nucleic Acids Research 44 (17), 8363-8375, 2016 | 61 | 2016 |
PRMT5-mediated arginine methylation of TDP1 for the repair of topoisomerase I covalent complexes I Rehman, SM Basu, SK Das, S Bhattacharjee, A Ghosh, Y Pommier, ... Nucleic acids research 46 (11), 5601-5617, 2018 | 57 | 2018 |
Discovery and mechanistic study of tailor-made quinoline derivatives as topoisomerase 1 poison with potent anticancer activity B Kundu, SK Das, S Paul Chowdhuri, S Pal, D Sarkar, A Ghosh, ... Journal of Medicinal Chemistry 62 (7), 3428-3446, 2019 | 55 | 2019 |