| BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, O Shalem, ... Nature 527 (7577), 192-197, 2015 | 914 | 2015 |
| Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors J Grünewald, R Zhou, SP Garcia, S Iyer, CA Lareau, MJ Aryee, JK Joung Nature 569 (7756), 433-437, 2019 | 544 | 2019 |
| In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates K Musunuru, AC Chadwick, T Mizoguchi, SP Garcia, JE DeNizio, ... Nature 593 (7859), 429-434, 2021 | 499 | 2021 |
| CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells IC Kurt, R Zhou, S Iyer, SP Garcia, BR Miller, LM Langner, J Grünewald, ... Nature biotechnology 39 (1), 41-46, 2021 | 442 | 2021 |
| In vivo CRISPR editing with no detectable genome-wide off-target mutations P Akcakaya, ML Bobbin, JA Guo, J Malagon-Lopez, K Clement, SP Garcia, ... Nature 561 (7723), 416-419, 2018 | 336 | 2018 |
| High levels of AAV vector integration into CRISPR-induced DNA breaks KS Hanlon, BP Kleinstiver, SP Garcia, MP Zaborowski, A Volak, SE Spirig, ... Nature communications 10 (1), 4439, 2019 | 329 | 2019 |
| Transcriptional diversity during lineage commitment of human blood progenitors L Chen, M Kostadima, JHA Martens, G Canu, SP Garcia, E Turro, ... Science 345 (6204), 1251033, 2014 | 329 | 2014 |
| CRISPR DNA base editors with reduced RNA off-target and self-editing activities J Grünewald, R Zhou, S Iyer, CA Lareau, SP Garcia, MJ Aryee, JK Joung Nature biotechnology 37 (9), 1041-1048, 2019 | 280 | 2019 |
| Assessment of computational methods for the analysis of single-cell ATAC-seq data H Chen, C Lareau, T Andreani, ME Vinyard, SP Garcia, K Clement, ... Genome biology 20, 1-25, 2019 | 261 | 2019 |
| A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing J Grünewald, R Zhou, CA Lareau, SP Garcia, S Iyer, BR Miller, ... Nature Biotechnology 38 (7), 861-864, 2020 | 222 | 2020 |
| Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss B György, C Nist-Lund, B Pan, Y Asai, KD Karavitaki, BP Kleinstiver, ... Nature medicine 25 (7), 1123-1130, 2019 | 178 | 2019 |
| GReEn: a tool for efficient compression of genome resequencing data AJ Pinho, D Pratas, SP Garcia Nucleic acids research 40 (4), e27-e27, 2012 | 133 | 2012 |
| Genome analysis with inter-nucleotide distances V Afreixo, CAC Bastos, AJ Pinho, SP Garcia, PJSG Ferreira Bioinformatics 25 (23), 3064-3070, 2009 | 103 | 2009 |
| Multivariate phase space reconstruction by nearest neighbor embedding with different time delays SP Garcia, JS Almeida Physical Review E 72 (2), 027205, 2005 | 78 | 2005 |
| Vangl2/RhoA signaling pathway regulates stem cell self-renewal programs and growth in rhabdomyosarcoma MN Hayes, K McCarthy, A Jin, ML Oliveira, S Iyer, SP Garcia, S Sindiri, ... Cell stem cell 22 (3), 414-427. e6, 2018 | 66 | 2018 |
| tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish MS Ignatius, MN Hayes, FE Moore, Q Tang, SP Garcia, PR Blackburn, ... Elife 7, e37202, 2018 | 60 | 2018 |
| On finding minimal absent words AJ Pinho, PJSG Ferreira, SP Garcia, JMOS Rodrigues BMC bioinformatics 10, 1-11, 2009 | 57 | 2009 |
| Nearest neighbor embedding with different time delays SP Garcia, JS Almeida Physical Review E 71 (3), 037204, 2005 | 42 | 2005 |
| Minimal absent words in prokaryotic and eukaryotic genomes SP Garcia, AJ Pinho, JMOS Rodrigues, CAC Bastos, PJSG Ferreira PLoS One 6 (1), e16065, 2011 | 38 | 2011 |
| GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy LN Kasiewicz, S Biswas, A Beach, H Ren, C Dutta, AM Mazzola, E Rohde, ... Nature Communications 14 (1), 2776, 2023 | 36 | 2023 |
