| Overcoming expression and purification problems of RhoGDI using a family of “parallel” expression vectors P Sheffield, S Garrard, Z Derewenda Protein expression and purification 15 (1), 34-39, 1999 | 738 | 1999 |
| A HUPO test sample study reveals common problems in mass spectrometry–based proteomics AW Bell, EW Deutsch, CE Au, RE Kearney, R Beavis, S Sechi, T Nilsson, ... Nature methods 6 (6), 423-430, 2009 | 406 | 2009 |
| Borg proteins control septin organization and are negatively regulated by Cdc42 G Joberty, RR Perlungher, PJ Sheffield, M Kinoshita, M Noda, T Haystead, ... Nature cell biology 3 (10), 861-866, 2001 | 248 | 2001 |
| Borg/septin interactions and the assembly of mammalian septin heterodimers, trimers, and filaments PJ Sheffield, CJ Oliver, BE Kremer, S Sheng, Z Shao, IG Macara Journal of Biological Chemistry 278 (5), 3483-3488, 2003 | 228 | 2003 |
| Protein crystallization by rational mutagenesis of surface residues: Lys to Ala mutations promote crystallization of RhoGDI KL Longenecker, SM Garrard, PJ Sheffield, ZS Derewenda Acta Crystallographica Section D: Biological Crystallography 57 (5), 679-688, 2001 | 201 | 2001 |
| Crystal structure of brefeldin A esterase, a bacterial homolog of the mammalian hormone-sensitive lipase Y Wei, JA Contreras, P Sheffield, T Osterlund, U Derewenda, RE Kneusel, ... Nature structural biology 6 (4), 340-345, 1999 | 177 | 1999 |
| Molecular basis of mitomycin C resistance in Streptomyces: structure and function of the MRD protein TW Martin, Z Dauter, Y Devedjiev, P Sheffield, F Jelen, M He, ... Structure 10 (7), 933-942, 2002 | 40 | 2002 |
| Molecular fabrication JC Braman, PJ Sheffield, G Fischer US Patent 10,662,424, 2020 | 38 | 2020 |
| Structure of the BH domain from graf and its implications for Rho GTPase recognition KL Longenecker, B Zhang, U Derewenda, PJ Sheffield, Z Dauter, ... Journal of Biological Chemistry 275 (49), 38605-38610, 2000 | 35 | 2000 |
| Probing the substrate specificity of the intracellular brain platelet-activating factor acetylhydrolase YS Ho, PJ Sheffield, J Masuyama, H Arai, J Li, J Aoki, K Inoue, ... Protein engineering 12 (8), 693-700, 1999 | 32 | 1999 |
| Expression, purification, and crystallization of the RGS-like domain from the Rho nucleotide exchange factor, PDZ-RhoGEF, using the surface entropy reduction approach SM Garrard, KL Longenecker, ME Lewis, PJ Sheffield, ZS Derewenda Protein Expression and Purification 21 (3), 412-416, 2001 | 31 | 2001 |
| Homologs of the α‐and β‐subunits of mammalian brain platelet‐activating factor acetylhydrolase Ib in the Drosophila melanogaster genome PJ Sheffield, S Garrard, M Caspi, J Aoki, H Arai, U Derewenda, K Inoue, ... Proteins: Structure, Function, and Bioinformatics 39 (1), 1-8, 2000 | 29 | 2000 |
| Preparation and crystal structure of the recombinant α1/α2 catalytic heterodimer of bovine brain platelet-activating factor acetylhydrolase Ib PJ Sheffield, TWP McMullen, J Li, YS Ho, SM Garrard, U Derewenda, ... Protein engineering 14 (7), 513-519, 2001 | 24 | 2001 |
| The functional implications of the dimerization of the catalytic subunits of the mammalian brain platelet-activating factor acetylhydrolase (Ib) TWP McMullen, J Li, PJ Sheffield, J Aoki, TW Martin, H Arai, K Inoue, ... Protein Engineering 13 (12), 865-871, 2000 | 17 | 2000 |
| Expression, purification and crystallization of a BH domain from the GTPase regulatory protein associated with focal adhesion kinase PJ Sheffield, U Derewenda, J Taylor, TJ Parsons, ZS Derewenda Acta Crystallographica Section D: Biological Crystallography 55 (1), 356-359, 1999 | 8 | 1999 |
| An integrated strategy for the discovery of drug targets by the analysis of protein–protein interactions JM Peltier, S Askovic, RR Becklin, CL Chepanoske, YSJ Ho, V Kery, S Lai, ... International Journal of Mass Spectrometry 238 (2), 119-130, 2004 | 7 | 2004 |
| Seamless assembly of DNA parts into functional devices and higher order multi-device systems JC Braman, PJ Sheffield PLoS One 14 (6), e0199653, 2019 | 4 | 2019 |
| A rapid combinatorial approach to assembling synthetic prokaryotic and eukaryotic protein expression vectors R Mullinax, SE Johns, D Rhodes, V Zhang, N McKinney, KA Felts, ... Synthetic Biology: Methods and Protocols, 457-468, 2018 | 2 | 2018 |
| Increased Activity of Porcine Pancreatic Phospholipase A2 by Designed Long-Range Electrostatic Stabilization of the Transition State PJ Sheffield, KM Bhat, AJ Owen, B Perry, IG Sumner, J Warwicker Biochemical and biophysical research communications 216 (3), 778-784, 1995 | 1 | 1995 |
| Amplifying oligonucleotides and producing libraries of dual guide constructs JC Braman, PJ Sheffield, H Hogrefe US Patent 11,718,847, 2023 | | 2023 |
