Small molecule regulators of autophagy identified by an image-based high-throughput screen L Zhang, J Yu, H Pan, P Hu, Y Hao, W Cai, H Zhu, AD Yu, X Xie, D Ma, ... Proceedings of the National Academy of Sciences 104 (48), 19023-19028, 2007 | 515 | 2007 |
Epicardial FSTL1 reconstitution regenerates the adult mammalian heart K Wei, V Serpooshan, C Hurtado, M Diez-Cunado, M Zhao, S Maruyama, ... Nature 525 (7570), 479-485, 2015 | 505 | 2015 |
Dissecting super-enhancer hierarchy based on chromatin interactions J Huang, K Li, W Cai, X Liu, Y Zhang, SH Orkin, J Xu, GC Yuan Nature communications 9 (1), 943, 2018 | 216 | 2018 |
Small molecule inhibitors of mammalian thioredoxin reductase W Cai, L Zhang, Y Song, B Wang, B Zhang, X Cui, G Hu, Y Liu, J Wu, ... Free Radical Biology and Medicine 52 (2), 257-265, 2012 | 182 | 2012 |
Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells E Willems, J Cabral-Teixeira, D Schade, W Cai, P Reeves, PJ Bushway, ... Cell stem cell 11 (2), 242-252, 2012 | 146 | 2012 |
Curcumin targeting the thioredoxin system elevates oxidative stress in HeLa cells W Cai, B Zhang, D Duan, J Wu, J Fang Toxicology and applied pharmacology 262 (3), 341-348, 2012 | 116 | 2012 |
Coordinate Nodal and BMP inhibition directs Baf60c-dependent cardiomyocyte commitment W Cai, S Albini, K Wei, E Willems, RM Guzzo, M Tsuda, L Giordani, ... Genes & development 27 (21), 2332-2344, 2013 | 56 | 2013 |
Endomorphins, endogenous opioid peptides, provide antioxidant defense in the brain against free radical-induced damage X Lin, DJ Yang, WQ Cai, QY Zhao, YF Gao, Q Chen, R Wang Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1639 (3), 195-202, 2003 | 47 | 2003 |
A Nodal-to-TGFβ cascade exerts biphasic control over cardiopoiesis W Cai, RM Guzzo, K Wei, E Willems, H Davidovics, M Mercola Circulation research 111 (7), 876-881, 2012 | 41 | 2012 |
Enhancer dependence of cell-type–specific gene expression increases with developmental age W Cai, J Huang, Q Zhu, BE Li, D Seruggia, P Zhou, M Nguyen, Y Fujiwara, ... Proceedings of the National Academy of Sciences 117 (35), 21450-21458, 2020 | 35 | 2020 |
Engineered murine HSCs reconstitute multi-lineage hematopoiesis and adaptive immunity YF Lu, P Cahan, S Ross, J Sahalie, PM Sousa, BK Hadland, W Cai, ... Cell reports 17 (12), 3178-3192, 2016 | 31 | 2016 |
aYAP modRNA reduces cardiac inflammation and hypertrophy in a murine ischemia-reperfusion model J Chen, Q Ma, JS King, Y Sun, B Xu, X Zhang, S Zohrabian, H Guo, W Cai, ... Life Science Alliance 3 (1), 2020 | 28 | 2020 |
Developmental origin of age-related coronary artery disease MM Wei K, Diaz-Trelles R, Liu Q, Diez-Cunado M, Scimia MC, Cai W, Sawada J ... Cardiovascular Research 107 (2), 278-94, 2015 | 26* | 2015 |
Mapping the evolving landscape of super-enhancers during cell differentiation Y Kai, BE Li, M Zhu, GY Li, F Chen, Y Han, HJ Cha, SH Orkin, W Cai, ... Genome Biology 22, 1-21, 2021 | 25 | 2021 |
Thioredoxin signaling pathways in cancer J Zhang, X Li, Z Zhao, W Cai, J Fang Antioxidants & Redox Signaling 38 (4), 403-424, 2023 | 23 | 2023 |
3, 4, 4′-Trihydroxy-trans-stilbene, an analogue of resveratrol, is a potent antioxidant and cytotoxic agent W Cai, L Zhang, Y Song, B Zhang, X Cui, G Hu, J Fang Free Radical Research 45 (11-12), 1379-1387, 2011 | 22 | 2011 |
Aloe-emodin alleviates doxorubicin-induced cardiotoxicity via inhibition of ferroptosis Y He, J Xi, J Fang, B Zhang, W Cai Free Radical Biology and Medicine 206, 13-21, 2023 | 9 | 2023 |
Cholesterol-derived glucocorticoids control early fate specification in embryonic stem cells J Cabral-Teixeira, A Martinez-Fernandez, W Cai, A Terzic, M Mercola, ... Stem cell research 15 (1), 88-95, 2015 | 9 | 2015 |
In vivo CRISPR/Cas9 screening identifies Pbrm1 as a regulator of myeloid leukemia development in mice BE Li, GY Li, W Cai, Q Zhu, D Seruggia, Y Fujiwara, CR Vakoc, SH Orkin Blood Advances 7 (18), 5281-5293, 2023 | 2 | 2023 |
Synthesis and evaluation of piperine analogs as thioredoxin reductase inhibitors to cause oxidative stress-induced cancer cell apoptosis M Zhong, L Chen, Y Tao, J Zhao, B Chang, F Zhang, J Tu, W Cai, B Zhang Bioorganic Chemistry 138, 106589, 2023 | 2 | 2023 |