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Thomas Shum
Thomas Shum
The Brigham and Women's Hospital, Harvard Medical School
在 bwh.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Constitutive signaling from an engineered IL7 receptor promotes durable tumor elimination by tumor-redirected T cells
T Shum, B Omer, H Tashiro, RL Kruse, DL Wagner, K Parikh, Z Yi, ...
Cancer discovery 7 (11), 1238-1247, 2017
2542017
Treatment of acute myeloid leukemia with T cells expressing chimeric antigen receptors directed to C-type lectin-like molecule 1
H Tashiro, T Sauer, T Shum, K Parikh, M Mamonkin, B Omer, RH Rouce, ...
Molecular Therapy 25 (9), 2202-2213, 2017
1362017
Enhanced detection of olefins using ambient ionization mass spectrometry: Ag+ adducts of biologically relevant alkenes
AU Jackson, T Shum, E Sokol, A Dill, RG Cooks
Analytical and bioanalytical chemistry 399, 367-376, 2011
912011
Determinants of chest radiography sensitivity for COVID-19: a multi-institutional study in the United States
S Stephanie, T Shum, H Cleveland, SR Challa, A Herring, FL Jacobson, ...
Radiology: Cardiothoracic Imaging 2 (5), e200337, 2020
862020
HBsAg-redirected T cells exhibit antiviral activity in HBV-infected human liver chimeric mice
RL Kruse, T Shum, H Tashiro, M Barzi, Z Yi, C Whitten-Bauer, X Legras, ...
Cytotherapy 20 (5), 697-705, 2018
832018
Comprehensive approach for identifying the T cell subset origin of CD3 and CD28 antibody–activated chimeric antigen receptor–modified T cells
M Schmueck-Henneresse, B Omer, T Shum, H Tashiro, M Mamonkin, ...
The Journal of Immunology 199 (1), 348-362, 2017
522017
A homing system targets therapeutic T cells to brain cancer
H Samaha, A Pignata, K Fousek, J Ren, FW Lam, F Stossi, J Dubrulle, ...
Nature 561 (7723), 331-337, 2018
462018
Strategies for enhancing adoptive T-cell immunotherapy against solid tumors using engineered cytokine signaling and other modalities
T Shum, RL Kruse, CM Rooney
Expert opinion on biological therapy 18 (6), 653-664, 2018
352018
Adult and cord blood-derived high-affinity gB-CAR-T cells effectively react against human cytomegalovirus infections
H Olbrich, SJ Theobald, C Slabik, L Gerasch, A Schneider, M Mach, ...
Human Gene Therapy 31 (7-8), 423-439, 2020
322020
A costimulatory CAR improves TCR-based cancer immunotherapy
B Omer, MG Cardenas, T Pfeiffer, R Daum, M Huynh, S Sharma, ...
Cancer immunology research 10 (4), 512-524, 2022
192022
Chimeric antigen receptor signaling domains differentially regulate proliferation and native T cell receptor function in virus-specific T cells
B Omer, PA Castillo, H Tashiro, T Shum, MTA Huynh, M Cardenas, ...
Frontiers in medicine 5, 343, 2018
172018
In situ liver expression of HBsAg/CD3-bispecific antibodies for HBV immunotherapy
RL Kruse, T Shum, X Legras, M Barzi, FP Pankowicz, S Gottschalk, ...
Molecular therapy Methods & clinical development 7, 32-41, 2017
172017
Endoscopic-mediated, biliary hydrodynamic injection mediating clinically relevant levels of gene delivery in pig liver
RL Kruse, Y Huang, T Shum, L Bai, H Ding, ZZ Wang, FM Selaru, ...
Gastrointestinal endoscopy 94 (6), 1119-1130. e4, 2021
52021
A backpack revs up T-cell activity
T Shum, HE Heslop
Nature Biotechnology 36 (8), 702-703, 2018
52018
CAR T cells targeted with a high affinity scFv against the HCMV glycoprotein Gb as adoptive T cell therapy after hematopoietic stem cell transplantation
R Stripecke, L Gerasch, S Theobald, BS Sundarasetty, M Mamonkin, ...
Blood 128 (22), 5721, 2016
42016
Antibody based gene therapy with tissue-directed expression
RL Kruse, K Bissig, SMG Gottschalk, TCT Shum
US Patent 11,566,063, 2023
32023
Phase I Trial of GD2. CAR T Cells Combined with a Novel Interleukin-7 Signal Modulator
B Omer, T Shum, J Foster, K Parikh, C Tat, M Shekar, A Vivekananthan, ...
2022 Tandem Meetings| Transplantation & Cellular Therapy Meetings of ASTCT …, 2022
32022
Determinants of chest X-Ray sensitivity for COVID-19
S Stephanie, T Shum, H Cleveland, SR Challa, A Herring, FL Jacobson
A multi-institutional study in the United States Radiol Cardiothorac Imaging …, 0
3
Chimeric antigen receptor therapy with reduced cytotoxicity for viral disease
RL Kruse, K Bissig, SMG Gottschalk, TCT Shum
US Patent 11,219,646, 2022
22022
Retraction note: a homing system targets therapeutic T cells to brain cancer
H Samaha, A Pignata, K Fousek, J Ren, FW Lam, F Stossi, J Dubrulle, ...
Nature 567 (7746), 132-132, 2019
22019
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