Mapping the melatonin receptor. 6. Melatonin agonists and antagonists derived from 6 H-isoindolo [2, 1-a] indoles, 5, 6-dihydroindolo [2, 1-a] isoquinolines, and 6, 7-dihydro-5 … R Faust, PJ Garratt, R Jones, LK Yeh, A Tsotinis, M Panoussopoulou, ... Journal of medicinal chemistry 43 (6), 1050-1061, 2000 | 207 | 2000 |
Synthesis, lipophilicity and biological evaluation of indole-containing derivatives of 1, 3, 4-thiadiazole and 1, 2, 4-triazole A Varvaresou, T Siatra-Papastaikoudi, A Tsotinis, A Tsantili-Kakoulidou, ... Il Farmaco 53 (5), 320-326, 1998 | 200 | 1998 |
Mapping the melatonin receptor. 4. Comparison of the binding affinities of a series of substituted phenylalkyl amides PJ Garratt, S Travard, S Vonhoff, A Tsotinis, D Sugden Journal of medicinal chemistry 39 (9), 1797-1805, 1996 | 100 | 1996 |
Design, synthesis, and trypanocidal activity of new aminoadamantane derivatives I Papanastasiou, A Tsotinis, N Kolocouris, SR Prathalingam, JM Kelly Journal of medicinal chemistry 51 (5), 1496-1500, 2008 | 78 | 2008 |
Antileishmanial ring-substituted ether phospholipids N Avlonitis, E Lekka, A Detsi, M Koufaki, T Calogeropoulou, E Scoulica, ... Journal of medicinal chemistry 46 (5), 755-767, 2003 | 63 | 2003 |
C1 ‘-cycloalkyl side chain pharmacophore in tetrahydrocannabinols DP Papahatjis, VR Nahmias, SP Nikas, T Andreou, SO Alapafuja, ... Journal of medicinal chemistry 50 (17), 4048-4060, 2007 | 55 | 2007 |
Mapping the Melatonin Receptor. 7. Subtype Selective Ligands Based on β-Substituted N-Acyl-5-methoxytryptamines and β-Substituted N-Acyl-5-methoxy-1 … A Tsotinis, M Vlachou, DP Papahatjis, T Calogeropoulou, SP Nikas, ... Journal of medicinal chemistry 49 (12), 3509-3519, 2006 | 54 | 2006 |
Design, synthesis, and melatoninergic activity of new azido-and isothiocyanato-substituted indoles A Tsotinis, PA Afroudakis, K Davidson, A Prashar, D Sugden Journal of medicinal chemistry 50 (25), 6436-6440, 2007 | 53 | 2007 |
Synthesis and antimicrobial evaluation of indole containing derivatives of 1, 3, 4-thiadiazole, 1, 2, 4-triazole and their open-chain counterparts. A Tsotinis, A Varvaresou, T Calogeropoulou, T Siatra-Papastaikoudi, ... Arzneimittel-forschung 47 (3), 307-310, 1997 | 53 | 1997 |
Design and synthesis of bioactive 1, 2-annulated adamantane derivatives G Zoidis, A Tsotinis, N Kolocouris, JM Kelly, SR Prathalingam, L Naesens, ... Organic & biomolecular chemistry 6 (17), 3177-3185, 2008 | 52 | 2008 |
GABAA modulating neurosteroids T Calogeropoulou, A Tsotinis, C Souli, A Makriyannis US Patent 7,064,116, 2006 | 52 | 2006 |
Fabrication and characterization of electrospun nanofibers for the modified release of the chronobiotic hormone melatonin M Vlachou, S Kikionis, A Siamidi, K Tragou, S Kapoti, E Ioannou, ... Current Drug Delivery 16 (1), 79-85, 2019 | 46 | 2019 |
Synthesis of compounds as melatonin agonists and antagonists PJ Garratt, A Tsotinis Mini Reviews in Medicinal Chemistry 7 (10), 1075-1088, 2007 | 42 | 2007 |
Synthesis and Antiretroviral Evaluation of New Alkoxy and Aryloxy Phosphate Derivatives of 3 ‘-Azido-3 ‘-deoxythymidine A Tsotinis, T Calogeropoulou, M Koufaki, C Souli, J Balzarini, E De Clercq, ... Journal of medicinal chemistry 39 (17), 3418-3422, 1996 | 38 | 1996 |
Development and Characterization of Eudragit®-Based Electrospun Nanofibrous Mats and Their Formulation into Nanofiber Tablets for the Modified Release of … M Vlachou, S Kikionis, A Siamidi, S Kyriakou, A Tsotinis, E Ioannou, ... Pharmaceutics 11 (9), 480, 2019 | 37 | 2019 |
Synthesis of new alkylaminoalkyl thiosemicarbazones of 3-acetylindole and their effect on DNA synthesis and cell proliferation T Siatra-Papastaikoudi, A Tsotinis, CP Raptopoulou, C Sambani, ... European journal of medicinal chemistry 30 (2), 107-114, 1995 | 37 | 1995 |
A facile synthesis of C2-substituted pyrrolo [2, 3-f] quinolines with cytotoxic activity A Tsotinis, M Vlachou, S Zouroudis, A Jeney, F Timar, DE Thurston, ... Letters in Drug Design & Discovery 2 (3), 189-192, 2005 | 36 | 2005 |
Preparation and reactions of some (trimethylsilyl) cyclopropenes. Synthesis of in-out tricyclic [n. 3.2. 02, 4] compounds, potential precursors to cyclopropaparacyclophanes PJ Garratt, A Tsotinis The Journal of Organic Chemistry 55 (1), 84-88, 1990 | 36 | 1990 |
Alternative pharmacological interventions that limit myocardial infarction I Andreadou, EK Iliodromitis, M Koufaki, D Farmakis, A Tsotinis, ... Current medicinal chemistry 15 (30), 3204-3213, 2008 | 34 | 2008 |
Novel 17β-Substituted Conformationally Constrained Neurosteroids that Modulate GABAA Receptors C Souli, N Avlonitis, T Calogeropoulou, A Tsotinis, G Maksay, T Bíró, ... Journal of medicinal chemistry 48 (16), 5203-5214, 2005 | 34 | 2005 |