Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes L Zou, SJ Elledge Science 300 (5625), 1542-1548, 2003 | 3469 | 2003 |
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations SV Sharma, DY Lee, B Li, MP Quinlan, F Takahashi, S Maheswaran, ... Cell 141 (1), 69-80, 2010 | 2699 | 2010 |
DNA damage sensing by the ATM and ATR kinases A Maréchal, L Zou Cold Spring Harbor perspectives in biology 5 (9), a012716, 2013 | 1679 | 2013 |
RNA m6A methylation regulates the ultraviolet-induced DNA damage response Y Xiang, B Laurent, CH Hsu, S Nachtergaele, Z Lu, W Sheng, C Xu, ... Nature 543 (7646), 573-576, 2017 | 796 | 2017 |
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin L Zou, D Cortez, SJ Elledge Genes & development 16 (2), 198-208, 2002 | 642 | 2002 |
Replication protein A-mediated recruitment and activation of Rad17 complexes L Zou, D Liu, SJ Elledge Proceedings of the National Academy of Sciences 100 (24), 13827-13832, 2003 | 567 | 2003 |
Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors RL Flynn, KE Cox, M Jeitany, H Wakimoto, AR Bryll, NJ Ganem, F Bersani, ... Science 347 (6219), 273-277, 2015 | 522 | 2015 |
Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks B Shiotani, L Zou Molecular cell 33 (5), 547-558, 2009 | 470 | 2009 |
Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase L Zou, B Stillman Molecular and cellular biology 20 (9), 3086-3096, 2000 | 463 | 2000 |
RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response A Maréchal, L Zou Cell research 25 (1), 9-23, 2015 | 458 | 2015 |
Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin L Zou, B Stillman Science 280 (5363), 593-596, 1998 | 454 | 1998 |
Checking on the fork: the DNA-replication stress-response pathway AJ Osborn, SJ Elledge, L Zou Trends in cell biology 12 (11), 509-516, 2002 | 451 | 2002 |
Cancer-specific retargeting of BAF complexes by a prion-like domain G Boulay, GJ Sandoval, N Riggi, S Iyer, R Buisson, B Naigles, ME Awad, ... Cell 171 (1), 163-178. e19, 2017 | 415 | 2017 |
TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA RL Flynn, RC Centore, RJ O’Sullivan, R Rai, A Tse, Z Songyang, S Chang, ... Nature 471 (7339), 532-536, 2011 | 405 | 2011 |
MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells D Lemaçon, J Jackson, A Quinet, JR Brickner, S Li, S Yazinski, Z You, ... Nature communications 8 (1), 860, 2017 | 388 | 2017 |
Regulation of homologous recombination by RNF20-dependent H2B ubiquitination K Nakamura, A Kato, J Kobayashi, H Yanagihara, S Sakamoto, ... Molecular cell 41 (5), 515-528, 2011 | 369 | 2011 |
ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells SA Yazinski, V Comaills, R Buisson, MM Genois, HD Nguyen, CK Ho, ... Genes & development 31 (3), 318-332, 2017 | 365 | 2017 |
ATR: a master conductor of cellular responses to DNA replication stress RL Flynn, L Zou Trends in biochemical sciences 36 (3), 133-140, 2011 | 355 | 2011 |
Distinct but concerted roles of ATR, DNA-PK, and Chk1 in countering replication stress during S phase R Buisson, JL Boisvert, CH Benes, L Zou Molecular cell 59 (6), 1011-1024, 2015 | 338 | 2015 |
ATR autophosphorylation as a molecular switch for checkpoint activation S Liu, B Shiotani, M Lahiri, A Maréchal, A Tse, CCY Leung, JNM Glover, ... Molecular cell 43 (2), 192-202, 2011 | 315 | 2011 |