| Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance L Madisen, AR Garner, D Shimaoka, AS Chuong, NC Klapoetke, L Li, ... Neuron 85 (5), 942-958, 2015 | 1031 | 2015 |
| Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex T Iwasato, A Datwani, AM Wolf, H Nishiyama, Y Taguchi, S Tonegawa, ... Nature 406 (6797), 726-731, 2000 | 555 | 2000 |
| Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders? F Nicoletti, V Bruno, A Copani, G Casabona, T Knöpfel Trends in neurosciences 19 (7), 267-271, 1996 | 542 | 1996 |
| Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmitters S Charpak, BH Gähwiler, KQ Do, T Knöpfel Nature 347 (6295), 765-767, 1990 | 494 | 1990 |
| Glial protein S100B modulates long-term neuronal synaptic plasticity H Nishiyama, T Knöpfel, S Endo, S Itohara Proceedings of the National Academy of Sciences 99 (6), 4037-4042, 2002 | 371 | 2002 |
| Metabotropic glutamate receptors: novel targets for drug development T Knoepfel, R Kuhn, H Allgeier Journal of medicinal chemistry 38 (9), 1417-1426, 1995 | 329 | 1995 |
| Imaging brain electric signals with genetically targeted voltage-sensitive fluorescent proteins W Akemann, H Mutoh, A Perron, J Rossier, T Knöpfel Nature methods 7 (8), 643-649, 2010 | 315 | 2010 |
| Imaging neural circuit dynamics with a voltage-sensitive fluorescent protein W Akemann, H Mutoh, A Perron, YK Park, Y Iwamoto, T Knöpfel Journal of neurophysiology 108 (8), 2323-2337, 2012 | 283 | 2012 |
| Design and characterization of a DNA‐encoded, voltage‐sensitive fluorescent protein R Sakai, V Repunte‐Canonigo, CD Raj, T Knöpfel European Journal of Neuroscience 13 (12), 2314-2318, 2001 | 277 | 2001 |
| Genetically encoded optical indicators for the analysis of neuronal circuits T Knöpfel Nature Reviews Neuroscience 13 (10), 687-700, 2012 | 246 | 2012 |
| Engineering and characterization of an enhanced fluorescent protein voltage sensor D Dimitrov, Y He, H Mutoh, BJ Baker, L Cohen, W Akemann, T Knöpfel PloS one 2 (5), e440, 2007 | 241 | 2007 |
| Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7 G Sansig, TJ Bushell, VRJ Clarke, A Rozov, N Burnashev, C Portet, ... Journal of Neuroscience 21 (22), 8734-8745, 2001 | 235 | 2001 |
| Morphological and electrophysiological properties of GABAergic and non-GABAergic cells in the deep cerebellar nuclei M Uusisaari, K Obata, T Knopfel Journal of neurophysiology 97 (1), 901-911, 2007 | 234 | 2007 |
| Synaptic integration in a model of cerebellar granule cells F Gabbiani, J Midtgaard, T Knopfel Journal of neurophysiology 72 (2), 999-1009, 1994 | 220 | 1994 |
| Involvement of protein synthesis and degradation in long-term potentiation of Schaffer collateral CA1 synapses A Karpova, M Mikhaylova, U Thomas, T Knöpfel, T Behnisch Journal of Neuroscience 26 (18), 4949-4955, 2006 | 217 | 2006 |
| Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells V Bruno, A Copani, T Knöpfel, R Kuhn, G Casabona, P Dell'Albani, ... Neuropharmacology 34 (8), 1089-1098, 1995 | 212 | 1995 |
| The Second Intracellular Loop of Metabotropic Glutamate Receptor 1 Cooperates with the Other Intracellular Domains to Control Coupling to G-proteins (∗) J Gomeza, C Joly, R Kuhn, T Knöpfel, J Bockaert, JP Pin Journal of Biological Chemistry 271 (4), 2199-2205, 1996 | 208 | 1996 |
| Electrotonic coupling of excitable and nonexcitable cells in the heart revealed by optogenetics TA Quinn, P Camelliti, EA Rog-Zielinska, U Siedlecka, T Poggioli, ... Proceedings of the National Academy of Sciences 113 (51), 14852-14857, 2016 | 203 | 2016 |
| Engineering of a genetically encodable fluorescent voltage sensor exploiting fast Ci-VSP voltage-sensing movements A Lundby, H Mutoh, D Dimitrov, W Akemann, T Knöpfel PloS one 3 (6), e2514, 2008 | 183 | 2008 |
| The neuroprotective activity of group-II metabotropic glutamate receptors requires new protein synthesis and involves a glial–neuronal signaling V Bruno, FX Sureda, M Storto, G Casabona, A Caruso, T Knopfel, R Kuhn, ... Journal of Neuroscience 17 (6), 1891-1897, 1997 | 178 | 1997 |
