Prediction-corrected visual predictive checks for diagnosing nonlinear mixed-effects models M Bergstrand, AC Hooker, JE Wallin, MO Karlsson The AAPS journal 13, 143-151, 2011 | 1325 | 2011 |
Xpose—an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM EN Jonsson, MO Karlsson Computer methods and programs in biomedicine 58 (1), 51-64, 1998 | 1149 | 1998 |
The FIELDS instrument suite for Solar Probe Plus: measuring the coronal plasma and magnetic field, plasma waves and turbulence, and radio signatures of solar transients SD Bale, K Goetz, PR Harvey, P Turin, JW Bonnell, T Dudok de Wit, ... Space science reviews 204, 49-82, 2016 | 683 | 2016 |
Modeling and simulation workbench for NONMEM: tutorial on Pirana, PsN, and Xpose RJ Keizer, MO Karlsson, A Hooker CPT: pharmacometrics & systems pharmacology 2 (6), 1-9, 2013 | 663 | 2013 |
Importance of shrinkage in empirical bayes estimates for diagnostics: problems and solutions RM Savic, MO Karlsson The AAPS journal 11, 558-569, 2009 | 650 | 2009 |
Model of chemotherapy-induced myelosuppression with parameter consistency across drugs LE Friberg, A Henningsson, H Maas, L Nguyen, MO Karlsson Journal of clinical oncology 20 (24), 4713-4721, 2002 | 639 | 2002 |
The importance of modeling interoccasion variability in population pharmacokinetic analyses MO Karlsson, LB Sheiner Journal of pharmacokinetics and biopharmaceutics 21 (6), 735-750, 1993 | 628 | 1993 |
Diagnosing model diagnostics MO Karlsson, RM Savic Clinical Pharmacology & Therapeutics 82 (1), 17-20, 2007 | 601 | 2007 |
Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies RM Savic, DM Jonker, T Kerbusch, MO Karlsson Journal of pharmacokinetics and pharmacodynamics 34, 711-726, 2007 | 595 | 2007 |
The axial double probe and fields signal processing for the MMS mission RE Ergun, S Tucker, J Westfall, KA Goodrich, DM Malaspina, D Summers, ... Space Science Reviews 199, 167-188, 2016 | 587 | 2016 |
Conditional weighted residuals (CWRES): a model diagnostic for the FOCE method AC Hooker, CE Staatz, MO Karlsson Pharmaceutical research 24, 2187-2197, 2007 | 407 | 2007 |
Pharmacokinetics and safety of intravenous voriconazole in children after single-or multiple-dose administration TJ Walsh, MO Karlsson, T Driscoll, AG Arguedas, P Adamson, ... Antimicrobial agents and chemotherapy 48 (6), 2166-2172, 2004 | 407 | 2004 |
Handling data below the limit of quantification in mixed effect models M Bergstrand, MO Karlsson The AAPS journal 11, 371-380, 2009 | 363 | 2009 |
Automated covariate model building within NONMEM EN Jonsson, MO Karlsson Pharmaceutical research 15, 1463-1468, 1998 | 351 | 1998 |
Assessment of actual significance levels for covariate effects in NONMEM U Wählby, EN Jonsson, MO Karlsson Journal of pharmacokinetics and pharmacodynamics 28, 231-252, 2001 | 350 | 2001 |
Likelihood based approaches to handling data below the quantification limit using NONMEM VI JE Ahn, MO Karlsson, A Dunne, TM Ludden Journal of pharmacokinetics and pharmacodynamics 35, 401-421, 2008 | 346 | 2008 |
Irinotecan pathway genotype analysis to predict pharmacokinetics RHJ Mathijssen, S Marsh, MO Karlsson, R Xie, SD Baker, J Verweij, ... Clinical cancer research 9 (9), 3246-3253, 2003 | 325 | 2003 |
Model evaluation of continuous data pharmacometric models: metrics and graphics THT Nguyen, MS Mouksassi, N Holford, N Al‐Huniti, I Freedman, ... CPT: pharmacometrics & systems pharmacology 6 (2), 87-109, 2017 | 312 | 2017 |
Implementing pharmacogenomics in Europe: design and implementation strategy of the ubiquitous pharmacogenomics consortium CH van der Wouden, A Cambon‐Thomsen, E Cecchin, KC Cheung, ... Clinical Pharmacology & Therapeutics 101 (3), 341-358, 2017 | 294 | 2017 |
Population pharmacokinetic analysis of voriconazole plasma concentration data from pediatric studies MO Karlsson, I Lutsar, PA Milligan Antimicrobial agents and chemotherapy 53 (3), 935-944, 2009 | 253 | 2009 |