Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis H Li, H Zhu, C Xu, J Yuan Cell 94 (4), 491-501, 1998 | 6005 | 1998 |
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β T Nakagawa, H Zhu, N Morishima, E Li, J Xu, BA Yankner, J Yuan Nature 403 (6765), 98-103, 2000 | 4397 | 2000 |
Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3 M Miura, H Zhu, R Rotello, EA Hartwieg, J Yuan Cell 75 (4), 653-660, 1993 | 1994 | 1993 |
Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death L Wang, M Miura, L Bergeron, H Zhu, J Yuan Cell 78 (5), 739-750, 1994 | 1107 | 1994 |
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE S Wang, M Miura, Y Jung, H Zhu, E Li, J Yuan Cell 92 (4), 501-509, 1998 | 879 | 1998 |
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor O Gozani, P Karuman, DR Jones, D Ivanov, J Cha, AA Lugovskoy, ... Cell 114 (1), 99-111, 2003 | 635 | 2003 |
RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS Y Ito, D Ofengeim, A Najafov, S Das, S Saberi, Y Li, J Hitomi, H Zhu, ... Science 353 (6299), 603-608, 2016 | 541 | 2016 |
Small molecule regulators of autophagy identified by an image-based high-throughput screen L Zhang, J Yu, H Pan, P Hu, Y Hao, W Cai, H Zhu, AD Yu, X Xie, D Ma, ... Proceedings of the National Academy of Sciences 104 (48), 19023-19028, 2007 | 515 | 2007 |
The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death P Karuman, O Gozani, RD Odze, XC Zhou, H Zhu, R Shaw, TP Brien, ... Molecular cell 7 (6), 1307-1319, 2001 | 417 | 2001 |
TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging D Xu, T Jin, H Zhu, H Chen, D Ofengeim, C Zou, L Mifflin, L Pan, P Amin, ... Cell 174 (6), 1477-1491. e19, 2018 | 354 | 2018 |
RIPK1 mediates a disease-associated microglial response in Alzheimer’s disease D Ofengeim, S Mazzitelli, Y Ito, JP DeWitt, L Mifflin, C Zou, S Das, ... Proceedings of the National Academy of Sciences 114 (41), E8788-E8797, 2017 | 328 | 2017 |
Identification and characterization of Ich-3, a member of the interleukin-1β converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE S Wang, M Miura, Y Jung, H Zhu, V Gagliardini, L Shi, AH Greenberg, ... Journal of Biological Chemistry 271 (34), 20580-20587, 1996 | 316 | 1996 |
Specific cleavage of α-fodrin during Fas-and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1β-converting enzyme/Ced-3 protease distinct from the poly … VL Cryns, L Bergeron, H Zhu, H Li, J Yuan Journal of Biological Chemistry 271 (49), 31277-31282, 1996 | 282 | 1996 |
A novel role for RIP1 kinase in mediating TNFα production DE Christofferson, Y Li, J Hitomi, W Zhou, C Upperman, H Zhu, SA Gerber, ... Cell death & disease 3 (6), e320-e320, 2012 | 244 | 2012 |
Activation of caspase-2 in apoptosis H Li, L Bergeron, V Cryns, MS Pasternack, H Zhu, L Shi, A Greenberg, ... Journal of Biological Chemistry 272 (34), 21010-21017, 1997 | 221 | 1997 |
Essential role for caspase-8 in transcription-independent apoptosis triggered by p53 HF Ding, YL Lin, G McGill, P Juo, H Zhu, J Blenis, J Yuan, DE Fisher Journal of Biological Chemistry 275 (49), 38905-38911, 2000 | 196 | 2000 |
Caspase-11 regulates cell migration by promoting Aip1–Cofilin-mediated actin depolymerization J Li, WM Brieher, ML Scimone, SJ Kang, H Zhu, H Yin, UH von Andrian, ... Nature cell biology 9 (3), 276-286, 2007 | 165 | 2007 |
Liposome‐encapsulated dichloromethylene diphosphonate induces macrophage apoptosis in vivo and in vitro M Naito, H Nagai, S Kawano, H Umezu, H Zhu, H Moriyama, T Yamamoto, ... Journal of leukocyte biology 60 (3), 337-344, 1996 | 158 | 1996 |
Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death H Xia, A Najafov, J Geng, L Galan-Acosta, X Han, Y Guo, B Shan, ... Journal of Cell Biology 210 (5), 705-716, 2015 | 116 | 2015 |
Caspase-11 controls interleukin-1β release through degradation of TRPC1 BF Py, M Jin, BN Desai, A Penumaka, H Zhu, M Kober, A Dietrich, ... Cell reports 6 (6), 1122-1128, 2014 | 101 | 2014 |