Single-stranded DNA-binding protein hSSB1 is critical for genomic stability DJ Richard, E Bolderson, L Cubeddu, RIM Wadsworth, K Savage, ... Nature 453 (7195), 677-681, 2008 | 283 | 2008 |
Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB protein ID Kerr, RIM Wadsworth, L Cubeddu, W Blankenfeldt, JH Naismith, ... The EMBO journal, 2003 | 167 | 2003 |
Human single-stranded DNA binding proteins are essential for maintaining genomic stability NW Ashton, E Bolderson, L Cubeddu, KJ O’Byrne, DJ Richard BMC molecular biology 14, 1-20, 2013 | 118 | 2013 |
hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex DJ Richard, K Savage, E Bolderson, L Cubeddu, S So, M Ghita, DJ Chen, ... Nucleic acids research 39 (5), 1692-1702, 2011 | 98 | 2011 |
hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity DJ Richard, L Cubeddu, AJ Urquhart, A Bain, E Bolderson, D Menon, ... Nucleic acids research 39 (9), 3643-3651, 2011 | 96 | 2011 |
It takes two to tango: the structure and function of LIM, RING, PHD and MYND domains JM Matthews, M Bhati, E Lehtomaki, RE Mansfield, L Cubeddu, ... Current pharmaceutical design 15 (31), 3681-3696, 2009 | 95 | 2009 |
DNA damage detection by an archaeal single-stranded DNA-binding protein L Cubeddu, MF White Journal of molecular biology 353 (3), 507-516, 2005 | 77 | 2005 |
hSSB1 (NABP2/OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway N Paquet, MN Adams, V Leong, NW Ashton, C Touma, R Gamsjaeger, ... Nucleic acids research 43 (18), 8817-8829, 2015 | 48 | 2015 |
The archaeal XPB protein is a ssDNA-dependent ATPase with a novel partner JD Richards, L Cubeddu, J Roberts, H Liu, MF White Journal of molecular biology 376 (3), 634-644, 2008 | 44 | 2008 |
hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress N Paquet, MN Adams, NW Ashton, C Touma, R Gamsjaeger, L Cubeddu, ... Scientific reports 6 (1), 27446, 2016 | 39 | 2016 |
Homomeric ring assemblies of eukaryotic Sm proteins have affinity for both RNA and DNA: crystal structure of an oligomeric complex of yeast SmF BM Collins, L Cubeddu, N Naidoo, SJ Harrop, GD Kornfeld, IW Dawes, ... Journal of Biological Chemistry 278 (19), 17291-17298, 2003 | 39 | 2003 |
Human single-stranded DNA binding protein 1 (hSSB1, OBFC2B), a critical component of the DNA damage response LV Croft, E Bolderson, MN Adams, S El-Kamand, R Kariawasam, ... Seminars in cell & developmental biology 86, 121-128, 2019 | 36 | 2019 |
The structural basis of DNA binding by the single-stranded DNA-binding protein from Sulfolobus solfataricus R Gamsjaeger, R Kariawasam, AX Gimenez, C Touma, E McIlwain, ... Biochemical Journal 465 (2), 337-346, 2015 | 35 | 2015 |
The binding of syndapin SH3 domain to dynamin proline-rich domain involves short and long distance elements L Luo, J Xue, A Kwan, R Gamsjaeger, J Wielens, L von Kleist, L Cubeddu, ... Journal of Biological Chemistry 291 (18), 9411-9424, 2016 | 30 | 2016 |
A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution C Touma, R Kariawasam, AX Gimenez, RE Bernardo, NW Ashton, ... Nucleic acids research 44 (16), 7963-7973, 2016 | 29 | 2016 |
Contribution of DEAF1 structural domains to the interaction with the breast cancer oncogene LMO4 L Cubeddu, S Joseph, DJ Richard, JM Matthews PloS one 7 (6), e39218, 2012 | 29 | 2012 |
Sequence specificity of single-stranded DNA-binding proteins: a novel DNA microarray approach HP Morgan, P Estibeiro, MA Wear, KEA Max, U Heinemann, L Cubeddu, ... Nucleic acids research 35 (10), e75, 2007 | 29 | 2007 |
A distinct ssDNA/RNA binding interface in the Nsp9 protein from SARS‐CoV‐2 S El‐Kamand, MD Du Plessis, N Breen, L Johnson, S Beard, AH Kwan, ... Proteins: Structure, Function, and Bioinformatics 90 (1), 176-185, 2022 | 27 | 2022 |
Single-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangs RK Pandita, TT Chow, D Udayakumar, AL Bain, L Cubeddu, CR Hunt, ... Cancer research 75 (5), 858-869, 2015 | 24 | 2015 |
Dictyostelium discoideum as expression host: isotopic labeling of a recombinant glycoprotein for NMR studies L Cubeddu, CX Moss, JD Swarbrick, AA Gooley, KL Williams, PMG Curmi, ... Protein Expression and Purification 19 (3), 335-342, 2000 | 24 | 2000 |