Genetics of rheumatoid arthritis contributes to biology and drug discovery Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ... Nature 506 (7488), 376-381, 2014 | 2497 | 2014 |
A gene-based association method for mapping traits using reference transcriptome data ER Gamazon, HE Wheeler, KP Shah, SV Mozaffari, K Aquino-Michaels, ... Nature genetics 47 (9), 1091-1098, 2015 | 1623 | 2015 |
Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data JC Denny, L Bastarache, MD Ritchie, RJ Carroll, R Zink, JD Mosley, ... Nature biotechnology 31 (12), 1102-1111, 2013 | 1007 | 2013 |
A catalog of genetic loci associated with kidney function from analyses of a million individuals M Wuttke, Y Li, M Li, KB Sieber, MF Feitosa, M Gorski, A Tin, L Wang, ... Nature genetics 51 (6), 957-972, 2019 | 625 | 2019 |
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function C Pattaro, A Teumer, M Gorski, AY Chu, M Li, V Mijatovic, M Garnaas, ... Nature communications 7 (1), 10023, 2016 | 489 | 2016 |
R PheWAS: data analysis and plotting tools for phenome-wide association studies in the R environment RJ Carroll, L Bastarache, JC Denny Bioinformatics 30 (16), 2375-2376, 2014 | 382 | 2014 |
Mapping ICD-10 and ICD-10-CM codes to phecodes: workflow development and initial evaluation P Wu, A Gifford, X Meng, X Li, H Campbell, T Varley, J Zhao, R Carroll, ... JMIR medical informatics 7 (4), e14325, 2019 | 355 | 2019 |
Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record WQ Wei, LA Bastarache, RJ Carroll, JE Marlo, TJ Osterman, ER Gamazon, ... PloS one 12 (7), e0175508, 2017 | 320 | 2017 |
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels A Tin, J Marten, VL Halperin Kuhns, Y Li, M Wuttke, H Kirsten, KB Sieber, ... Nature genetics 51 (10), 1459-1474, 2019 | 297 | 2019 |
Portability of an algorithm to identify rheumatoid arthritis in electronic health records RJ Carroll, WK Thompson, AE Eyler, AM Mandelin, T Cai, RM Zink, ... Journal of the American Medical Informatics Association 19 (e1), e162-e169, 2012 | 242 | 2012 |
Increased monocyte count as a cellular biomarker for poor outcomes in fibrotic diseases: a retrospective, multicentre cohort study MKD Scott, K Quinn, Q Li, R Carroll, H Warsinske, F Vallania, S Chen, ... The Lancet Respiratory Medicine 7 (6), 497-508, 2019 | 204 | 2019 |
Phenotype risk scores identify patients with unrecognized Mendelian disease patterns L Bastarache, JJ Hughey, S Hebbring, J Marlo, W Zhao, WT Ho, ... Science 359 (6381), 1233-1239, 2018 | 197 | 2018 |
Genome-wide association studies identify genetic loci associated with albuminuria in diabetes A Teumer, A Tin, R Sorice, M Gorski, NC Yeo, AY Chu, M Li, Y Li, ... Diabetes 65 (3), 803-817, 2016 | 171 | 2016 |
Effect of oral methylprednisolone on decline in kidney function or kidney failure in patients with IgA nephropathy: the TESTING randomized clinical trial J Lv, MG Wong, MA Hladunewich, V Jha, LS Hooi, H Monaghan, M Zhao, ... Jama 327 (19), 1888-1898, 2022 | 159 | 2022 |
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria A Teumer, Y Li, S Ghasemi, BP Prins, M Wuttke, T Hermle, A Giri, ... Nature communications 10 (1), 4130, 2019 | 159 | 2019 |
Naïve electronic health record phenotype identification for rheumatoid arthritis RJ Carroll, AE Eyler, JC Denny AMIA annual symposium proceedings 2011, 189, 2011 | 152 | 2011 |
GA4GH: International policies and standards for data sharing across genomic research and healthcare HL Rehm, AJH Page, L Smith, JB Adams, G Alterovitz, LJ Babb, ... Cell genomics 1 (2), 2021 | 148 | 2021 |
Experiments and model for serration statistics in low-entropy, medium-entropy and high-entropy alloys R Carroll, C Lee, CW Tsai, JW Yeh, J Antonaglia, BAW Brinkman, ... Scientific reports 5 (1), 16997, 2015 | 141 | 2015 |
GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network B Namjou, T Lingren, Y Huang, S Parameswaran, BL Cobb, IB Stanaway, ... BMC medicine 17, 1-19, 2019 | 130 | 2019 |
Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis K Ishigaki, S Sakaue, C Terao, Y Luo, K Sonehara, K Yamaguchi, ... Nature genetics 54 (11), 1640-1651, 2022 | 129 | 2022 |