| KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients KS Gajiwala, JC Wu, J Christensen, GD Deshmukh, W Diehl, JP DiNitto, ... Proceedings of the National Academy of Sciences 106 (5), 1542-1547, 2009 | 451 | 2009 |
| In vitro and in vivo modifications of recombinant and human IgG antibodies H Liu, G Ponniah, HM Zhang, C Nowak, A Neill, N Gonzalez-Lopez, ... mAbs 6 (5), 1145-1154, 2014 | 170 | 2014 |
| Structural Switch of Lysyl-tRNA Synthetase between Translation and Transcription Y Ofir-Birin, P Fang, SP Bennett, HM Zhang, J Wang, I Rachmin, ... Molecular Cell, 2012 | 153 | 2012 |
| Epitope mapping of a 95 kDa antigen in complex with antibody by solution-phase amide backbone hydrogen/deuterium exchange monitored by fourier transform ion cyclotron resonance … Q Zhang, LAN Willison, P Tripathi, SK Sathe, KH Roux, MR Emmett, ... Analytical chemistry, 2011 | 135 | 2011 |
| Unique domain appended to vertebrate tRNA synthetase is essential for vascular development X Xu, Y Shi, HM Zhang, EC Swindell, AG Marshall, M Guo, S Kishi, ... Nature Communications 3, 681, 2012 | 118 | 2012 |
| Enhanced digestion efficiency, peptide ionization efficiency, and sequence resolution for protein hydrogen/deuterium exchange monitored by Fourier transform ion cyclotron … HM Zhang, S Kazazic, TM Schaub, JD Tipton, MR Emmett, AG Marshall Analytical chemistry 80 (23), 9034-9041, 2008 | 113 | 2008 |
| Fast reversed-phase liquid chromatography to reduce back exchange and increase throughput in H/D exchange monitored by FT-ICR mass spectrometry HM Zhang, GM Bou-Assaf, MR Emmett, AG Marshall Journal of the American Society for Mass Spectrometry 20 (3), 520-524, 2009 | 80 | 2009 |
| Dispersed disease-causing neomorphic mutations on a single protein promote the same localized conformational opening W He, HM Zhang, YE Chong, M Guo, AG Marshall, XL Yang Proceedings of the National Academy of Sciences 108 (30), 12307-12312, 2011 | 75 | 2011 |
| Automated data reduction for hydrogen/deuterium exchange experiments, enabled by high-resolution Fourier transform ion cyclotron resonance mass spectrometry S Kazazic, HM Zhang, TM Schaub, MR Emmett, CL Hendrickson, ... Journal of the American Society for Mass Spectrometry 21 (4), 550-558, 2010 | 75 | 2010 |
| Simultaneous reduction and digestion of proteins with disulfide bonds for hydrogen/deuterium exchange monitored by mass spectrometry HM Zhang, SM McLoughlin, SD Frausto, H Tang, MR Emmett, ... Analytical chemistry 82 (4), 1450-1454, 2010 | 72 | 2010 |
| Computing H/D-Exchange rates of single residues from data of proteolytic fragments E Althaus, S Canzar, C Ehrler, M Emmett, A Karrenbauer, A Marshall, ... BMC bioinformatics 11 (1), 424, 2010 | 48 | 2010 |
| Mapping of the allosteric network in the regulation of α-isopropylmalate synthase from Mycobacterium tuberculosis by the feedback inhibitor l-leucine: Solution-phase H/D … PA Frantom, HM Zhang, MR Emmett, AG Marshall, JS Blanchard Biochemistry 48 (31), 7457-7464, 2009 | 47 | 2009 |
| Structural context for mobilization of a human tRNA synthetase from its cytoplasmic complex P Fang, HM Zhang, R Shapiro, AG Marshall, P Schimmel, XL Yang, ... Proceedings of the National Academy of Sciences 108 (20), 8239-8244, 2011 | 44 | 2011 |
| Nucleotide-induced conformational changes of tetradecameric GroEL mapped by H/D exchange monitored by FT-ICR mass spectrometry Q Zhang, J Chen, K Kuwajima, HM Zhang, F Xian, NL Young, ... Scientific reports 3, 2013 | 36 | 2013 |
| Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry HM Zhang, X Yu, MJ Greig, KS Gajiwala, JC Wu, W Diehl, EA Lunney, ... Protein Science 19 (4), 703-715, 2010 | 32 | 2010 |
| Computing H/D-exchange speeds of single residues from data of peptic fragments E Althaus, S Canzar, MR Emmett, A Karrenbauer, AG Marshall, ... Proceedings of the 2008 ACM symposium on Applied computing, 1273-1277, 2008 | 23 | 2008 |
| Uncovering of a short internal peptide activates a tRNA synthetase procytokine PS Lee, HM Zhang, AG Marshall, XL Yang, P Schimmel Journal of Biological Chemistry 287 (24), 20504-20508, 2012 | 12 | 2012 |
| Warfarin untargeted metabolomics study identifies novel procoagulant ethanolamide plasma lipids H Deguchi, DJ Elias, S Trauger, HM Zhang, E Kalisiak, G Siuzdak, ... British journal of haematology 165 (3), 409-412, 2014 | 10 | 2014 |
| Discrete fitting of hydrogen-deuterium-exchange data of overlapping fragments E Althaus, S Canzar, C Ehrler, M Emmett, A Karrenbauer, A Marshall, ... BIOCOMP, 496-502, 2009 | 10 | 2009 |
| In vitro and in vivo modifications of recombinant and human IgG antibodies. MAbs 2014; 6: 1145-54; PMID: 25517300 H Liu, G Ponniah, HM Zhang, C Nowak, A Neill, N Gonzalez-Lopez, ... | 5 | |
