RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3 L Tavares, E Dimitrova, D Oxley, J Webster, R Poot, J Demmers, ... Cell 148 (4), 664-678, 2012 | 678 | 2012 |
The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements S Schoenfelder, M Furlan-Magaril, B Mifsud, F Tavares-Cadete, R Sugar, ... Genome research 25 (4), 582-597, 2015 | 465 | 2015 |
Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome S Schoenfelder, R Sugar, A Dimond, BM Javierre, H Armstrong, B Mifsud, ... Nature genetics 47 (10), 1179-1186, 2015 | 388 | 2015 |
Histone demethylases in chromatin biology and beyond E Dimitrova, AH Turberfield, RJ Klose EMBO reports 16 (12), 1620-1639, 2015 | 197 | 2015 |
The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9 A Dhayalan, R Tamas, I Bock, A Tattermusch, E Dimitrova, S Kudithipudi, ... Human molecular genetics 20 (11), 2195-2203, 2011 | 182 | 2011 |
The SET1 complex selects actively transcribed target genes via multivalent interaction with CpG island chromatin DA Brown, V Di Cerbo, A Feldmann, J Ahn, S Ito, NP Blackledge, ... Cell reports 20 (10), 2313-2327, 2017 | 92 | 2017 |
A continuous protein methyltransferase (G9a) assay for enzyme activity measurement and inhibitor screening A Dhayalan, E Dimitrova, P Rathert, A Jeltsch Journal of Biomolecular Screening 14 (9), 1129-1133, 2009 | 39 | 2009 |
FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment E Dimitrova, T Kondo, A Feldmann, M Nakayama, Y Koseki, R Konietzny, ... Elife 7, e37084, 2018 | 24 | 2018 |
A CpG island-encoded mechanism protects genes from premature transcription termination AL Hughes, AT Szczurek, JR Kelley, A Lastuvkova, AH Turberfield, ... Nature Communications 14 (1), 726, 2023 | 21 | 2023 |
Distinct roles for CKM–Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction E Dimitrova, A Feldmann, RH van der Weide, KD Flach, A Lastuvkova, ... Nature structural & molecular biology 29 (10), 1000-1010, 2022 | 14 | 2022 |
CDK-Mediator and FBXL19 prime developmental genes for activation by promoting atypical regulatory interactions A Feldmann, E Dimitrova, A Kenney, A Lastuvkova, RJ Klose Nucleic Acids Research 48 (6), 2942-2955, 2020 | 7 | 2020 |
Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells HG Asenjo, M Alcazar-Fabra, M Espinosa-Martínez, L Lopez-Onieva, ... Nature Communications 14 (1), 180, 2023 | 3 | 2023 |
Polycomb sustains promoters in a deep OFF-state by limiting PIC formation to counteract transcription AT Szczurek, E Dimitrova, JR Kelley, RJ Klose bioRxiv, 2023.06. 13.544762, 2023 | 2 | 2023 |
Polycomb repression during S/G2 phases restrain initiation of cell differentiation to the G1 phase of the cell cycle HG Asenjo, M Alcazar-Fabra, M Espinosa, L Lopez-Onieva, A Gallardo, ... bioRxiv, 2022.07. 26.501502, 2022 | | 2022 |
Recruitment and interplay between distinct polycomb repressive complexes 1 in embryonic stem cells and during neural lineage commitment EA Dimitrova University of Cambridge, 2013 | | 2013 |