Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB JC Scheuermann, AG de Ayala Alonso, K Oktaba, N Ly-Hartig, ... Nature 465 (7295), 243-247, 2010 | 872 | 2010 |
Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation RK McGinty, J Kim, C Chatterjee, RG Roeder, TW Muir Nature 453 (7196), 812-816, 2008 | 605 | 2008 |
RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells J Kim, M Guermah, RK McGinty, JS Lee, Z Tang, TA Milne, A Shilatifard, ... Cell 137 (3), 459-471, 2009 | 600 | 2009 |
Nucleosome structure and function RK McGinty, S Tan Chemical reviews 115 (6), 2255-2273, 2015 | 562 | 2015 |
Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction B Fierz, C Chatterjee, RK McGinty, M Bar-Dagan, DP Raleigh, TW Muir Nature chemical biology 7 (2), 113-119, 2011 | 502 | 2011 |
Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions AJ Ruthenburg, H Li, TA Milne, S Dewell, RK McGinty, M Yuen, ... Cell 145 (5), 692-706, 2011 | 402 | 2011 |
Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome RK McGinty, RC Henrici, S Tan Nature 514 (7524), 591-596, 2014 | 327 | 2014 |
Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation C Chatterjee, RK McGinty, B Fierz, TW Muir Nature chemical biology 6 (4), 267-269, 2010 | 268 | 2010 |
Auxiliary-mediated site-specific peptide ubiquitylation C Chatterjee, RK McGinty, JP Pellois, TW Muir Angewandte Chemie-International Edition 46 (16), 2814-2818, 2007 | 211 | 2007 |
SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53 Z Tang, WY Chen, M Shimada, UTT Nguyen, J Kim, XJ Sun, T Sengoku, ... Cell 154 (2), 297-310, 2013 | 175 | 2013 |
Structural basis of nucleosome-dependent cGAS inhibition JA Boyer, CJ Spangler, JD Strauss, AP Cesmat, P Liu, RK McGinty, ... Science 370 (6515), 450-454, 2020 | 171 | 2020 |
The n-SET domain of Set1 regulates H2B ubiquitylation-dependent H3K4 methylation J Kim, JA Kim, RK McGinty, UTT Nguyen, TW Muir, CD Allis, RG Roeder Molecular cell 49 (6), 1121-1133, 2013 | 160 | 2013 |
Structure–activity analysis of semisynthetic nucleosomes: mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B RK McGinty, M Köhn, C Chatterjee, KP Chiang, MR Pratt, TW Muir ACS chemical biology 4 (11), 958-968, 2009 | 131 | 2009 |
Recognition of the nucleosome by chromatin factors and enzymes RK McGinty, S Tan Current Opinion in Structural Biology 37, 54-61, 2016 | 123 | 2016 |
Structural basis for recognition of ubiquitylated nucleosome by Dot1L methyltransferase CJ Anderson, MR Baird, A Hsu, EH Barbour, Y Koyama, MJ Borgnia, ... Cell reports 26 (7), 1681-1690. e5, 2019 | 121 | 2019 |
Principles of nucleosome recognition by chromatin factors and enzymes RK McGinty, S Tan Current Opinion in Structural Biology 71, 16-26, 2021 | 87 | 2021 |
Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding A Skrajna, D Goldfarb, KM Kedziora, EM Cousins, GD Grant, CJ Spangler, ... Nucleic acids research 48 (17), 9415-9432, 2020 | 73 | 2020 |
A Semi-Synthetic Strategy to Generate Phosphorylated and Acetylated Histone H2B KP Chiang, MS Jensen, RK McGinty, TW Muir Chembiochem: a European journal of chemical biology 10 (13), 2182, 2009 | 71 | 2009 |
Histone monoubiquitylation position determines specificity and direction of enzymatic cross-talk with histone methyltransferases Dot1L and PRC2 SJ Whitcomb, B Fierz, RK McGinty, M Holt, T Ito, TW Muir, CD Allis Journal of Biological Chemistry 287 (28), 23718-23725, 2012 | 40 | 2012 |
Multivalent interactions by the Set8 histone methyltransferase with its nucleosome substrate TS Girish, RK McGinty, S Tan Journal of molecular biology 428 (8), 1531-1543, 2016 | 37 | 2016 |