| Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor MH Hatada, X Lu, ER Laird, J Green, JP Morgenstern, M Lou, CS Marr, ... Nature 377 (6544), 32-38, 1995 | 438 | 1995 |
| What do medicinal chemists actually make? A 50-year retrospective WP Walters, J Green, JR Weiss, MA Murcko Journal of medicinal chemistry 54 (19), 6405-6416, 2011 | 404 | 2011 |
| X-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor. AL Swain, MM Miller, J Green, DH Rich, J Schneider, SB Kent, ... Proceedings of the National Academy of Sciences 87 (22), 8805-8809, 1990 | 395 | 1990 |
| Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal. JE Ladbury, MA Lemmon, M Zhou, J Green, MC Botfield, J Schlessinger Proceedings of the National Academy of Sciences 92 (8), 3199-3203, 1995 | 343 | 1995 |
| Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control AM Aronov, Q Tang, G Martinez-Botella, GW Bemis, J Cao, G Chen, ... Journal of medicinal chemistry 52 (20), 6362-6368, 2009 | 186 | 2009 |
| Pyrazole compounds useful as protein kinase inhibitors D Bebbington, JD Charrier, J Golec, J Green, D Kay, R Knegtel, A Miller, ... US Patent 6,653,300, 2003 | 185* | 2003 |
| Protein kinase inhibitors and uses thereof YC Moon, J Green, R Davies, D Choquette, A Pierce, M Ledeboer US Patent 6,825,190, 2004 | 167 | 2004 |
| Synthetic, structural and biological studies of the ubiquitin system: the total chemical synthesis of ubiquitin R Ramage, J Green, TW Muir, OM Ogunjobi, S Love, K Shaw Biochemical journal 299 (1), 151-158, 1994 | 165 | 1994 |
| Hydroxyethylamine analogs of the p17/p24 substrate cleavage site are tight-binding inhibitors of HIV protease DH Rich, J Green, MV Toth, GR Marshall, SBH Kent Journal of Medicinal Chemistry 33 (5), 1285-1288, 1990 | 162 | 1990 |
| Interaction of p72syk with the γ and β Subunits of the High-Affinity Receptor for Immunoglobulin E, FcεRI L Shiue, J Green, OM Green, JL Karas, JP Morgenstern, MK Ram, ... Molecular and cellular biology 15 (1), 272-281, 1995 | 159 | 1995 |
| NG-2, 2, 5, 7, 8-pentamethylchroman-6-sulphonyl-L-arginine: A new acid labile derivative for peptide synthesis R Ramage, J Green Tetrahedron letters 28 (20), 2287-2290, 1987 | 156 | 1987 |
| Pyrrolopyridines useful as inhibitors of protein kinase M Ledeboer, M Wannamaker, L Farmer, T Wang, A Pierce, ... US Patent 8,921,376, 2014 | 154 | 2014 |
| Inhibitors of p38 FG Salituro, GW Bemis, J Green, JL Kofron US Patent 6,093,742, 2000 | 154* | 2000 |
| Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors AM Aronov, C Baker, GW Bemis, J Cao, G Chen, PJ Ford, UA Germann, ... Journal of medicinal chemistry 50 (6), 1280-1287, 2007 | 138 | 2007 |
| Pyrazole compositions useful as inhibitors of ERK M Hale, X Xie, J Green, J Cao, C Baker, F Maltais, J Janetka, G Bemis, ... US Patent 6,528,509, 2003 | 124 | 2003 |
| Substituted pyrrolo [2, 3-d] pyrimidines as inhibitors of protein kinases M Ledeboer, A Pierce, G Bemis, L Farmer, T Wang, D Messersmith, ... US Patent 8,633,205, 2014 | 122 | 2014 |
| Compositions useful as inhibitors of protein kinases JM Jimenez, J Green, H Gao, YC Moon, G Brenchley, R Knegtel, ... US Patent 7,700,609, 2010 | 121 | 2010 |
| Inhibitors of GSK-3 and crystal structures of GSK-3β protein and protein complexes E Ter Haar, L Swenson, J Green, MJ Arnost US Patent 7,666,647, 2010 | 112 | 2010 |
| An acid labile arginine derivative for peptide synthesis: NG-2, 2, 5, 7, 8-pentamethylchroman-6-sulphonyl-L-arginine R Ramage, J Green, AJ Blake Tetrahedron 47 (32), 6353-6370, 1991 | 94 | 1991 |
| Heterocyclic inhibitors of ERK2 and uses thereof J Cao, J Green, M Hale, F Maltais, J Straub, Q Tang, A Aronov US Patent 6,743,791, 2004 | 93 | 2004 |
