PKA: lessons learned after twenty years SS Taylor, P Zhang, JM Steichen, MM Keshwani, AP Kornev Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (7), 1271-1278, 2013 | 314 | 2013 |
Evolution of the eukaryotic protein kinases as dynamic molecular switches SS Taylor, MM Keshwani, JM Steichen, AP Kornev Philosophical Transactions of the Royal Society B: Biological Sciences 367 …, 2012 | 257 | 2012 |
Deciphering the structural basis of eukaryotic protein kinase regulation HS Meharena, P Chang, MM Keshwani, K Oruganty, AK Nene, N Kannan, ... PLoS biology 11 (10), e1001680, 2013 | 218 | 2013 |
Structure and allostery of the PKA RIIβ tetrameric holoenzyme P Zhang, EV Smith-Nguyen, MM Keshwani, MS Deal, AP Kornev, ... Science 335 (6069), 712-716, 2012 | 190 | 2012 |
The fractalkine/CX3CR1 system regulates β cell function and insulin secretion YS Lee, H Morinaga, JJ Kim, W Lagakos, S Taylor, M Keshwani, ... Cell 153 (2), 413-425, 2013 | 155 | 2013 |
Structural basis for the regulation of protein kinase A by activation loop phosphorylation JM Steichen, M Kuchinskas, MM Keshwani, J Yang, JA Adams, SS Taylor Journal of Biological Chemistry 287 (18), 14672-14680, 2012 | 110 | 2012 |
Release of SR proteins from CLK1 by SRPK1: a symbiotic kinase system for phosphorylation control of pre-mRNA splicing BE Aubol, G Wu, MM Keshwani, M Movassat, L Fattet, KJ Hertel, XD Fu, ... Molecular cell 63 (2), 218-228, 2016 | 97 | 2016 |
Liver-specific p70 S6 kinase depletion protects against hepatic steatosis and systemic insulin resistance EJ Bae, J Xu, G Bandyopadhyay, WS Lagakos, M Keshwani, JM Olefsky Journal of Biological Chemistry 287 (22), 18769-18780, 2012 | 80 | 2012 |
Calcium-Dependent and -Independent Stomatal Signaling Network and Compensatory Feedback Control of Stomatal Opening via Ca2+ Sensitivity Priming K Laanemets, B Brandt, J Li, E Merilo, YF Wang, MM Keshwani, SS Taylor, ... Plant physiology 163 (2), 504-513, 2013 | 69 | 2013 |
Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase AC Bastidas, MS Deal, JM Steichen, MM Keshwani, Y Guo, SS Taylor Journal of molecular biology 422 (2), 215-229, 2012 | 69 | 2012 |
Measurement of enzyme activity TK Harris, MM Keshwani Methods in enzymology 463, 57-71, 2009 | 64 | 2009 |
Cotranslational cis-phosphorylation of the COOH-terminal tail is a key priming step in the maturation of cAMP-dependent protein kinase MM Keshwani, C Klammt, S von Daake, Y Ma, AP Kornev, S Choe, ... Proceedings of the National Academy of Sciences 109 (20), E1221-E1229, 2012 | 57 | 2012 |
Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1) MM Keshwani, S von Daake, AC Newton, TK Harris, SS Taylor Journal of Biological Chemistry 286 (26), 23552-23558, 2011 | 52 | 2011 |
Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function MM Keshwani, BE Aubol, L Fattet, CT Ma, J Qiu, PA Jennings, XD Fu, ... Biochemical Journal 466 (2), 311-322, 2015 | 47 | 2015 |
Decoding the interactions regulating the active state mechanics of eukaryotic protein kinases HS Meharena, X Fan, LG Ahuja, MM Keshwani, CL McClendon, AM Chen, ... PLoS Biology 14 (11), e2000127, 2016 | 41 | 2016 |
N-terminus of the protein kinase CLK1 induces SR protein hyperphosphorylation BE Aubol, RM Plocinik, MM Keshwani, ML McGlone, JC Hagopian, ... Biochemical Journal 462 (1), 143-152, 2014 | 41 | 2014 |
Directional phosphorylation and nuclear transport of the splicing factor SRSF1 is regulated by an RNA recognition motif P Serrano, BE Aubol, MM Keshwani, S Forli, CT Ma, SK Dutta, M Geralt, ... Journal of molecular biology 428 (11), 2430-2445, 2016 | 39 | 2016 |
Single turnover autophosphorylation cycle of the PKA RIIβ holoenzyme P Zhang, MJ Knape, LG Ahuja, MM Keshwani, CC King, M Sastri, ... PLoS biology 13 (7), e1002192, 2015 | 39 | 2015 |
Identification of the degradation determinants of insulin receptor substrate 1 for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination X Xu, M Keshwani, K Meyer, A Sarikas, S Taylor, ZQ Pan Journal of Biological Chemistry 287 (48), 40758-40766, 2012 | 35 | 2012 |
Mobilization of a splicing factor through a nuclear kinase–kinase complex BE Aubol, MM Keshwani, L Fattet, JA Adams Biochemical Journal 475 (3), 677-690, 2018 | 28 | 2018 |